Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   GPW48_RS01930 Genome accession   NZ_LR738720
Coordinates   369154..369843 (+) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis isolate GD-0001     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 364154..374843
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GPW48_RS01905 - 364483..365826 (+) 1344 WP_074390039.1 DEAD/DEAH box helicase -
  GPW48_RS01910 - 365844..366068 (+) 225 WP_002936682.1 DUF4059 family protein -
  GPW48_RS01915 trxB 366082..366999 (+) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  GPW48_RS01920 - 367009..367548 (+) 540 WP_024385904.1 YceD family protein -
  GPW48_RS01925 gndA 367645..369072 (+) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  GPW48_RS01930 covR 369154..369843 (+) 690 WP_012027645.1 DNA-binding response regulator Regulator
  GPW48_RS01935 - 369933..371063 (+) 1131 WP_014636113.1 AI-2E family transporter -
  GPW48_RS01940 nrdR 371135..371626 (+) 492 WP_002938341.1 transcriptional regulator NrdR -
  GPW48_RS01945 - 371613..372764 (+) 1152 WP_029174426.1 replication initiation/membrane attachment protein -
  GPW48_RS01950 dnaI 372764..373663 (+) 900 WP_029174425.1 primosomal protein DnaI -
  GPW48_RS01955 - 373660..374373 (+) 714 WP_074390040.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=1129386 GPW48_RS01930 WP_012027645.1 369154..369843(+) (covR) [Streptococcus suis isolate GD-0001]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1129386 GPW48_RS01930 WP_012027645.1 369154..369843(+) (covR) [Streptococcus suis isolate GD-0001]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACTGAAGTTAGTCAATATGGGGAGGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment