Detailed information NTG1128309

Bioinformatically predicted

Overview

• Name: covR
• Type: Regulator
• Locus tag: FJH52_RS01975
• Genome accession: NZ_LR595848
• Coordinates: 382983..383672 (+)
• Length: 229 a.a.
• NCBI ID: WP_000518007.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4559 isolate 4559
• Function: repress comR expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	383740..385046	382983..383672	flank	68

Gene organization within MGE regions

Location: 382983..385046

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FJH52_RS01975	covR	382983..383672 (+)	690	WP_000518007.1	response regulator transcription factor	Regulator
FJH52_RS01980	-	383740..385046 (-)	1307	Protein_399	transposase	-

Sequence

Protein

• Length: 229 a.a.
• Molecular weight: 26896.17 Da
• Isoelectric Point: 6.9836

>NTDB_id=1128309 FJH52_RS01975 WP_000518007.1 382983..383672(+) (covR) [Streptococcus pneumoniae strain 4559 isolate 4559]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTIQE

Nucleotide

• Length: 690 bp

>NTDB_id=1128309 FJH52_RS01975 WP_000518007.1 382983..383672(+) (covR) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGATTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGTAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATTCAAGAATAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-114)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (154-226)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Streptococcus salivarius strain HSISS4	48.696	100	0.489
covR	Lactococcus lactis subsp. lactis strain DGCC12653	46.087	100	0.463