Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   M036_RS06060 Genome accession   NZ_CP005997
Coordinates   1167636..1168292 (+) Length   218 a.a.
NCBI ID   WP_003245194.1    Uniprot ID   A0AAE2VF25
Organism   Bacillus subtilis TO-A     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1162636..1173292
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M036_RS06035 (M036_05985) - 1163161..1164018 (+) 858 WP_080287684.1 ABC transporter permease subunit -
  M036_RS06040 (M036_05990) yjbB 1164125..1165342 (+) 1218 WP_010886478.1 MFS transporter -
  M036_RS06045 (M036_05995) yjbC 1165506..1166084 (+) 579 WP_003244921.1 GNAT family N-acetyltransferase -
  M036_RS06050 (M036_06000) spx 1166265..1166660 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  M036_RS06055 (M036_06005) yjbE 1166703..1167359 (-) 657 WP_003232944.1 TerC family protein -
  M036_RS21595 - 1167529..1167669 (+) 141 WP_119122854.1 hypothetical protein -
  M036_RS06060 (M036_06010) mecA 1167636..1168292 (+) 657 WP_003245194.1 adaptor protein MecA Regulator
  M036_RS21600 - 1168287..1168409 (-) 123 WP_003245684.1 hypothetical protein -
  M036_RS06065 (M036_06015) coiA 1168483..1169604 (+) 1122 WP_010886479.1 competence protein CoiA Machinery gene
  M036_RS06070 (M036_06020) pepF 1169834..1171663 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  M036_RS06075 (M036_06025) - 1171701..1171868 (-) 168 WP_003244944.1 hypothetical protein -
  M036_RS06085 (M036_06035) spxH 1172182..1173081 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25763.69 Da        Isoelectric Point: 4.1174

>NTDB_id=112805 M036_RS06060 WP_003245194.1 1167636..1168292(+) (mecA) [Bacillus subtilis TO-A]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=112805 M036_RS06060 WP_003245194.1 1167636..1168292(+) (mecA) [Bacillus subtilis TO-A]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

100

100

1

Multiple sequence alignment