Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGL23_RS02480 Genome accession   NZ_LR594049
Coordinates   535774..536463 (+) Length   229 a.a.
NCBI ID   WP_045505796.1    Uniprot ID   A0AAW3H5C9
Organism   Streptococcus gordonii strain NCTC10231     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 530774..541463
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL23_RS02460 (NCTC10231_00488) - 530863..531393 (+) 531 WP_048778391.1 YceD family protein -
  FGL23_RS02465 (NCTC10231_00489) - 531495..532976 (+) 1482 WP_061603617.1 flotillin family protein -
  FGL23_RS02470 (NCTC10231_00490) - 533042..534067 (+) 1026 WP_061603618.1 hypothetical protein -
  FGL23_RS02475 (NCTC10231_00491) gndA 534337..535761 (+) 1425 WP_061603619.1 NADP-dependent phosphogluconate dehydrogenase -
  FGL23_RS02480 (NCTC10231_00492) covR 535774..536463 (+) 690 WP_045505796.1 response regulator transcription factor Regulator
  FGL23_RS02485 (NCTC10231_00493) - 536822..539014 (+) 2193 WP_061603620.1 PTS transporter subunit IIBC -
  FGL23_RS02490 (NCTC10231_00494) - 539032..539847 (+) 816 WP_061603621.1 endonuclease/exonuclease/phosphatase family protein -
  FGL23_RS02495 (NCTC10231_00495) nrdR 540203..540676 (+) 474 WP_008808512.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26275.27 Da        Isoelectric Point: 5.1861

>NTDB_id=1127949 FGL23_RS02480 WP_045505796.1 535774..536463(+) (covR) [Streptococcus gordonii strain NCTC10231]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPAAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQRCSQLKVPTAYRNLRVDLKNHTVYRGDEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1127949 FGL23_RS02480 WP_045505796.1 535774..536463(+) (covR) [Streptococcus gordonii strain NCTC10231]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTTATCATGCTGGAATTACAAAAGGAAAGTTA
TCAAGTAGACCTAGCGGAAACAGGACAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTGAGTTTATTAAAACCTGCTGCAGTTATCATTGTAATG
GTGAGTCGAGAGGAAATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
TAGTGATTTGGTTGATAAAATATCTGCTATTTTTCGTGGGCGGGATTTTATCGATCAGAGATGTAGCCAGTTAAAAGTCC
CTACTGCTTATCGAAATCTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGGGATGAAATTATTGCTTTGACGAGA
CGAGAGTACGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGCCGTGAGCAACTGTTAGACCGAGTGTGGAA
GTATGAAAGTGCATCTGAGACTAATATAGTGGATGTATATATTCGCTATCTCCGCAGTAAAATCGATCTTCCAGGTCAAG
AAAGTTATATTAAAACCGTTCGTGGAATTGGTTATTCCATGCAGGGTTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

51.77

98.69

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445

Multiple sequence alignment