Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   FGL22_RS04420 Genome accession   NZ_LR594048
Coordinates   869000..870229 (+) Length   409 a.a.
NCBI ID   WP_022554539.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 864000..875229
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL22_RS04395 (NCTC11556_00907) - 864622..865899 (-) 1278 WP_046177959.1 hydroxymethylglutaryl-CoA reductase, degradative -
  FGL22_RS04400 (NCTC11556_00908) - 865880..867061 (-) 1182 WP_003062183.1 hydroxymethylglutaryl-CoA synthase -
  FGL22_RS04405 (NCTC11556_00909) - 867279..868118 (+) 840 WP_003054196.1 thymidylate synthase -
  FGL22_RS04410 (NCTC11556_00910) - 868199..868696 (+) 498 WP_065355422.1 dihydrofolate reductase -
  FGL22_RS04415 (NCTC11556_00911) - 868716..868886 (+) 171 WP_003054200.1 hypothetical protein -
  FGL22_RS04420 (NCTC11556_00912) clpX 869000..870229 (+) 1230 WP_022554539.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  FGL22_RS04425 (NCTC11556_00913) yihA 870239..870838 (+) 600 WP_003061604.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  FGL22_RS04430 (NCTC11556_00914) - 870982..871725 (+) 744 WP_037589873.1 hypothetical protein -
  FGL22_RS04435 (NCTC11556_00915) clpC 871782..873881 (-) 2100 WP_065355423.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FGL22_RS04440 (NCTC11556_00917) - 874379..874786 (-) 408 Protein_821 IS30 family transposase -
  FGL22_RS04445 - 874783..874998 (+) 216 Protein_822 IS30 family transposase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45034.46 Da        Isoelectric Point: 4.5866

>NTDB_id=1127921 FGL22_RS04420 WP_022554539.1 869000..870229(+) (clpX) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNSRKIDDNASYMQEISSEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1127921 FGL22_RS04420 WP_022554539.1 869000..870229(+) (clpX) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC11556]
ATGGCAGGAAATCGTACAAACGATATTAAAGTATATTGCTCATTTTGTGGTAAGAGCCAAGACGAAGTCAAAAAAATTAT
TGCAGGGAATAATGTTTTTATCTGTAATGAATGTGTGGCTTTGTCACAAGAAATTATTAAAGAAGAGTTGGCAGAAGAAG
TGTTAGCTGACCTAACAGAAGTTCCAAAACCAAAAGAACTCCTTGAGGTTTTAAACCAGTATGTTGTTGGTCAAGATCGT
GCCAAACGTGCTTTATCAGTAGCTGTTTACAATCATTACAAACGCGTGTCATTCACGGAAAGTCGTGATGATGAAGATGT
TGAATTGCAAAAATCAAACATTTTAATGATTGGTCCAACAGGTTCAGGAAAGACTTTTCTCGCTCAAACCTTAGCTAAGA
GCTTAAATGTTCCTTTTGCGATTGCTGATGCAACCTCACTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
CTTCTCAAGCTTATCCAAGCAGCTGATTATAATGTGGAACGAGCAGAGCGTGGTATCATCTATGTCGATGAAATTGATAA
GATTGCTAAAAAAGGTGAAAATGTGTCCATCACACGTGATGTTTCTGGTGAGGGAGTTCAACAGGCCTTGCTAAAAATCA
TTGAAGGAACGGTTGCTAGTGTTCCTCCTCAAGGCGGTCGTAAGCATCCAAATCAGGAAATGATTCAAATTGATACCAAG
AATATCTTGTTTATTGTTGGGGGAGCCTTTGATGGCATTGAAGACATTGTCAAACAACGTTTAGGAGAAAAAGTCATTGG
TTTTGGTCAAAACAGCCGAAAAATCGATGACAATGCTTCTTATATGCAAGAGATTAGTTCAGAAGATATCCAAAAATTTG
GTCTTATCCCAGAGTTTATTGGACGCTTGCCAGTCGTAGCTGCTCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACGGAACCAAGAAATGCCCTAGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGTGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCAAATAAAGCCATTGAGCGTAAGACAGGCGCGCGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.242

100

0.892
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.853

98.044

0.577

Multiple sequence alignment