Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FGL18_RS07865 Genome accession   NZ_LR594046
Coordinates   1631515..1632840 (-) Length   441 a.a.
NCBI ID   WP_138126232.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1626515..1637840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS07855 (NCTC6403_01618) raiA 1630250..1630798 (-) 549 WP_003061817.1 ribosome-associated translation inhibitor RaiA -
  FGL18_RS11015 (NCTC6403_01619) - 1630878..1631543 (-) 666 WP_138126230.1 ComF family protein -
  FGL18_RS07865 (NCTC6403_01620) comFA/cflA 1631515..1632840 (-) 1326 WP_138126232.1 DEAD/DEAH box helicase Machinery gene
  FGL18_RS07870 (NCTC6403_01621) - 1632896..1633534 (+) 639 WP_003062333.1 YigZ family protein -
  FGL18_RS07875 (NCTC6403_01622) cysK 1633638..1634573 (+) 936 WP_138126234.1 cysteine synthase A -
  FGL18_RS07880 (NCTC6403_01623) - 1634725..1635084 (-) 360 WP_138126236.1 S1 RNA-binding domain-containing protein -
  FGL18_RS07885 (NCTC6403_01624) - 1635084..1636484 (-) 1401 WP_138126238.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FGL18_RS07890 (NCTC6403_01625) - 1636521..1637162 (-) 642 WP_014612503.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49372.54 Da        Isoelectric Point: 9.7794

>NTDB_id=1127811 FGL18_RS07865 WP_138126232.1 1631515..1632840(-) (comFA/cflA) [Streptococcus dysgalactiae strain NCTC6403]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVIIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALIKSISQQRKTGCRLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYSNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1127811 FGL18_RS07865 WP_138126232.1 1631515..1632840(-) (comFA/cflA) [Streptococcus dysgalactiae strain NCTC6403]
ATGGAAGGTATTGAAAATAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAATCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGCGGCACTTACTACTGTCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CACCCTTTTCCCATAGCCAATTATCTTCAATGGAAGGGGATATTAACGCCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGAAAGACAGAGATGATTTATGGTGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCCAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGGGTTACTCTTTTACATGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCAGCACAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAACTAGAGAAGCTGACATTAGCTAGACGATTCCATGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGCCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTATTAAATCTA
TCAGTCAGCAAAGGAAAACAGGATGTCGACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAGCAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGCCTT
TCGTCAAGGAAAGAAAGGCATTTTGGTGACCACTACAATATTGGAAAGGGGTGTTACTTTCCCAGGCGTGGATGTCTTTG
TGCTAATGGCACAGCATAGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTGGGGAGATCTATCGAAAGG
CCAACAGGGAAGGTGTATTTCTTTCACGATGGGATTAGTCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTCGAATGATATGCCTCCTATGTCAACGATTTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(288-396)

DEAD/DEAH box helicase (DEAD)

(99-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae D39

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae R6

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae TIGR4

53.081

95.692

0.508
  comFA/cflA Streptococcus mitis NCTC 12261

51.628

97.506

0.503
  comFA/cflA Streptococcus mitis SK321

51.765

96.372

0.499
  comFA Lactococcus lactis subsp. cremoris KW2

45.366

92.971

0.422
  comFA Latilactobacillus sakei subsp. sakei 23K

37.587

97.732

0.367

Multiple sequence alignment