Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   FGL14_RS11380 Genome accession   NZ_LR594045
Coordinates   37521..37619 (+) Length   32 a.a.
NCBI ID   WP_014611913.1    Uniprot ID   A0A380JYX6
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 32521..42619
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL14_RS00300 (NCTC9413_00059) purE 33028..33516 (+) 489 WP_015016518.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  FGL14_RS00305 (NCTC9413_00060) purK 33503..34585 (+) 1083 WP_138083646.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  FGL14_RS00310 (NCTC9413_00061) - 34714..34941 (+) 228 WP_022554087.1 hypothetical protein -
  FGL14_RS00315 (NCTC9413_00062) purB 35089..36381 (+) 1293 WP_022554088.1 adenylosuccinate lyase -
  FGL14_RS00320 (NCTC9413_00063) comR 36523..37434 (+) 912 WP_003060893.1 XRE family transcriptional regulator Regulator
  FGL14_RS11380 (NCTC9413_00064) comS 37521..37619 (+) 99 WP_014611913.1 quorum-sensing system DWW-type pheromone Regulator
  FGL14_RS00325 (NCTC9413_00065) ruvB 37653..38651 (+) 999 WP_138083647.1 Holliday junction branch migration DNA helicase RuvB -
  FGL14_RS00330 (NCTC9413_00066) - 38786..39217 (+) 432 WP_003059365.1 low molecular weight protein-tyrosine-phosphatase -
  FGL14_RS00335 (NCTC9413_00067) - 39246..39647 (+) 402 WP_003049089.1 MORN repeat-containing protein -
  FGL14_RS00340 (NCTC9413_00068) - 39644..41419 (+) 1776 WP_003059359.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 32 a.a.        Molecular weight: 3771.59 Da        Isoelectric Point: 10.4764

>NTDB_id=1127769 FGL14_RS11380 WP_014611913.1 37521..37619(+) (comS) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413]
MFKKIKPYLLLAAVVAFKVARAMNEFDWWNLG

Nucleotide


Download         Length: 99 bp        

>NTDB_id=1127769 FGL14_RS11380 WP_014611913.1 37521..37619(+) (comS) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9413]
ATGTTTAAAAAAATCAAACCATATTTGTTATTAGCCGCAGTCGTTGCTTTCAAAGTTGCTCGTGCAATGAACGAATTTGA
TTGGTGGAACCTAGGGTGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A380JYX6

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS315

84.375

100

0.844

  comS Streptococcus pyogenes MGAS8232

45.161

96.875

0.437


Multiple sequence alignment