Detailed information NTG1127673

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FGL05_RS03890
• Genome accession: NZ_LR594044
• Coordinates: 788759..789988 (+)
• Length: 409 a.a.
• NCBI ID: WP_020916897.1
• Uniprot ID: A0AB33AMD1
• Organism: Streptococcus lutetiensis strain NCTC8796
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 783759..794988

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL05_RS03865 (NCTC8796_00816)	-	784352..785623 (-)	1272	WP_111712848.1	hydroxymethylglutaryl-CoA reductase, degradative	-
FGL05_RS03870 (NCTC8796_00817)	-	785613..786788 (-)	1176	WP_058813991.1	hydroxymethylglutaryl-CoA synthase	-
FGL05_RS03875 (NCTC8796_00818)	-	787116..787955 (+)	840	WP_111712847.1	thymidylate synthase	-
FGL05_RS03880 (NCTC8796_00819)	-	788038..788532 (+)	495	WP_020916898.1	dihydrofolate reductase	-
FGL05_RS03890 (NCTC8796_00821)	clpX	788759..789988 (+)	1230	WP_020916897.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
FGL05_RS03895 (NCTC8796_00822)	yihA	789999..790592 (+)	594	WP_043895055.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
FGL05_RS03900	-	790701..792109 (+)	1409	Protein_800	amino acid permease	-
FGL05_RS03905	mmuM	792120..793066 (+)	947	Protein_801	homocysteine S-methyltransferase	-
FGL05_RS03910 (NCTC8796_00829)	-	793099..793767 (-)	669	WP_043895254.1	YoaK family protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45224.79 Da
• Isoelectric Point: 4.5119

>NTDB_id=1127673 FGL05_RS03890 WP_020916897.1 788759..789988(+) (clpX) [Streptococcus lutetiensis strain NCTC8796]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQER
AKRALAVAVYNHYKRVSFAESRDEEDVELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDEDASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTTDDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDEDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSRVEVTKVRITKDAVEG
KDKPILEIA

Nucleotide

• Length: 1230 bp

>NTDB_id=1127673 FGL05_RS03890 WP_020916897.1 788759..789988(+) (clpX) [Streptococcus lutetiensis strain NCTC8796]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTTTGTGGAAAAAGCCAAGACGAAGTAAAAAAAATCAT
TGCCGGAAATAACGTATTTATCTGTAATGAATGTGTGGCTTTATCCCAAGAAATTATTAAAGAGGAGTTAGCAGAAGAAG
TTCTCGCAGATTTGGCTGAAGTTCCAAAACCAAAAGAATTATTAGCAACCCTCGATGAATATGTTGTCGGTCAAGAACGC
GCTAAACGTGCCCTCGCAGTGGCTGTATACAACCACTACAAACGTGTTTCATTTGCCGAAAGTCGTGATGAAGAAGATGT
TGAATTGCAAAAATCTAACATCTTATTGATTGGACCAACTGGTTCAGGGAAAACTTTCCTTGCTCAAACCTTGGCGAAAA
GTTTAAACGTTCCATTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGACGTTGAAAATATC
CTTTTGAAACTCATTCAAGCAGCTGATTTTAATATTGAACGCGCAGAACGTGGTATCATCTACGTGGATGAAATTGATAA
AATTGCCAAAAAAGGTGAAAATGTCTCAATCACTCGTGATGTTTCAGGCGAAGGTGTTCAACAAGCTCTTCTTAAAATTA
TTGAAGGAACAGTTGCTAGCGTGCCACCACAAGGTGGTCGTAAACACCCGAACCAAGAAATGATTCAAATCAATACTAAG
AATATCCTTTTCATCGTTGGTGGTGCTTTTGACGGTATTGAAGATATTGTTAAACAACGTCTCGGTGAAAAAGTTATTGG
TTTTGGTCAAAATAACCGTAAGATCGATGAAGATGCTTCTTATATGCAAGAAATTATCTCGGAAGATATTCAGAAATTTG
GTTTAATTCCTGAATTTATCGGACGTTTGCCAGTCGTTGCTGCCCTTGAACAATTGACAACAGATGATTTGGTACGAATC
TTGACAGAACCTCGTAATGCCTTGGTTAAACAATACCAAACGCTTCTATCATATGATGGTGTTGAGTTGGAATTTGATGA
AGATGCCCTTCAAGCTATTGCTAATAAAGCAATCGAACGTAAGACAGGTGCACGTGGACTTCGTTCAATCATTGAAGAAA
CAATGATGGATATCATGTTTGAAATTCCAAGTCGTGTAGAGGTCACTAAAGTCCGTATTACAAAAGATGCCGTTGAAGGC
AAAGATAAACCAATTTTAGAGATTGCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.853	98.044	0.577