Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   FGL16_RS03270 Genome accession   NZ_LR594043
Coordinates   609975..611324 (+) Length   449 a.a.
NCBI ID   WP_012027301.1    Uniprot ID   -
Organism   Streptococcus suis strain NCTC10237     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 604975..616324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL16_RS03245 (NCTC10237_00623) - 606086..606745 (-) 660 WP_014735626.1 amino acid ABC transporter permease -
  FGL16_RS03250 (NCTC10237_00624) - 606760..607458 (-) 699 WP_012028333.1 amino acid ABC transporter permease -
  FGL16_RS03255 (NCTC10237_00625) - 607473..608312 (-) 840 WP_012027305.1 transporter substrate-binding domain-containing protein -
  FGL16_RS03260 (NCTC10237_00626) - 608323..609084 (-) 762 WP_012027304.1 amino acid ABC transporter ATP-binding protein -
  FGL16_RS03265 (NCTC10237_00627) micA 609278..609982 (+) 705 WP_004298854.1 response regulator YycF Regulator
  FGL16_RS03270 (NCTC10237_00628) micB 609975..611324 (+) 1350 WP_012027301.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FGL16_RS03275 (NCTC10237_00629) vicX 611331..612134 (+) 804 WP_012027300.1 MBL fold metallo-hydrolase Regulator
  FGL16_RS03280 (NCTC10237_00630) - 612390..612662 (+) 273 WP_014735627.1 hypothetical protein -
  FGL16_RS03285 (NCTC10237_00631) - 612649..613950 (+) 1302 WP_014735628.1 ATP-binding cassette domain-containing protein -
  FGL16_RS03290 (NCTC10237_00632) pbp2b 614027..616102 (+) 2076 WP_014735629.1 penicillin-binding protein PBP2B -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51079.14 Da        Isoelectric Point: 4.4857

>NTDB_id=1127627 FGL16_RS03270 WP_012027301.1 609975..611324(+) (micB) [Streptococcus suis strain NCTC10237]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYWDNKQIKQLNQKVNALIEGNYADLLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1127627 FGL16_RS03270 WP_012027301.1 609975..611324(+) (micB) [Streptococcus suis strain NCTC10237]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATTGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATCTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCTAATTCCCTCAATGATTTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACACGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCAACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTGGCGCCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGATCTCCTTAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTATAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.725

97.105

0.677
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment