Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   FGL12_RS05640 Genome accession   NZ_LR594041
Coordinates   1162165..1163394 (-) Length   409 a.a.
NCBI ID   WP_008808666.1    Uniprot ID   A0AAP2K4Q6
Organism   Streptococcus gordonii strain NCTC9124     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1157165..1168394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS05615 (NCTC9124_01126) - 1158106..1158846 (-) 741 WP_012000544.1 alpha/beta hydrolase-fold protein -
  FGL12_RS05620 (NCTC9124_01127) - 1158896..1159720 (-) 825 WP_041789678.1 alpha/beta hydrolase -
  FGL12_RS05625 (NCTC9124_01128) - 1159814..1160611 (-) 798 WP_012000546.1 formate/nitrite transporter family protein -
  FGL12_RS05630 (NCTC9124_01129) - 1160739..1161428 (-) 690 WP_012000547.1 glucosaminidase domain-containing protein -
  FGL12_RS05635 (NCTC9124_01130) yihA 1161562..1162155 (-) 594 WP_012000548.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  FGL12_RS05640 (NCTC9124_01131) clpX 1162165..1163394 (-) 1230 WP_008808666.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  FGL12_RS05650 (NCTC9124_01132) - 1163603..1164115 (-) 513 WP_012000549.1 dihydrofolate reductase -
  FGL12_RS05655 (NCTC9124_01133) - 1164268..1164762 (-) 495 WP_012000550.1 hypothetical protein -
  FGL12_RS05660 (NCTC9124_01134) - 1164893..1165732 (-) 840 WP_012000551.1 thymidylate synthase -
  FGL12_RS05665 (NCTC9124_01135) - 1165831..1166790 (-) 960 WP_012000552.1 ROK family glucokinase -
  FGL12_RS05670 (NCTC9124_01136) - 1166965..1167810 (-) 846 WP_012000553.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45650.21 Da        Isoelectric Point: 4.4870

>NTDB_id=1127494 FGL12_RS05640 WP_008808666.1 1162165..1163394(-) (clpX) [Streptococcus gordonii strain NCTC9124]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1127494 FGL12_RS05640 WP_008808666.1 1162165..1163394(-) (clpX) [Streptococcus gordonii strain NCTC9124]
ATGCCTACAAATCGTAATGAAGAGATGATGGTATATTGTTCATTCTGTGGGAAGAACCAAGATGAAGTTCAAAAGATTAT
TGCGGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCACAAGAAATTATCCGTGAAGAATTAGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGCCAAGAGCGT
GCTAAAAGAGCGCTAGCTGTAGCGGTATATAATCACTACAAGCGCATTAATTTTCACGATAGTCGTGAAGAAGATGATGT
TGAATTGCAAAAATCAAATATCTTAATGATTGGTCCAACGGGTTCTGGAAAAACTTTTCTTGCTCAAACCTTGGCTAGAA
GTTTAAATGTACCTTTTGCGATTGCTGATGCGACAGCTTTAACAGAGGCTGGTTATGTCGGAGAAGACGTTGAAAATATC
CTTTTAAAACTTTTACAGGCGGCTGATTTCAATATTGAACGTGCAGAACGCGGAATCATATACGTAGATGAGATTGATAA
GATCGCTAAAAAGAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAGGCTCTCTTAAAAATTA
TTGAGGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAACATCCGCAGCAAGAAATGATTCAGGTTGATACCAAA
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGGATTGAAGAAATTGTAAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATCGATGAAAACGAGTCCTACATGCAAGCTATTATTGCTGAAGATATTCAAAAATTTG
GAATTATTCCTGAATTAATTGGTCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGATGACTTGGTTCGTATT
CTTCGTGAGCCTAAGAATGCTTTGGTTAAACAATACCAGGCTCTCTTGTCTTACGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATTGAGCGCAAAACTGGTGCTCGCGGTCTACGTTCTATCATCGAAGAAA
CCATGATGGATGTGATGTTCGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCCGAATTACTAAAGAAGCTGTTGATGGT
ACGGATAAACCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.575

100

0.856
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.105

98.044

0.57

Multiple sequence alignment