Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGL12_RS02490 Genome accession   NZ_LR594041
Coordinates   532802..533491 (+) Length   229 a.a.
NCBI ID   WP_012000010.1    Uniprot ID   A0AAP2NYS9
Organism   Streptococcus gordonii strain NCTC9124     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 527802..538491
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL12_RS02470 (NCTC9124_00492) - 528147..529016 (-) 870 WP_012000006.1 Rgg/GadR/MutR family transcriptional regulator -
  FGL12_RS02475 (NCTC9124_00493) - 529115..529645 (+) 531 WP_012000007.1 DUF177 domain-containing protein -
  FGL12_RS02480 (NCTC9124_00494) - 529748..531229 (+) 1482 WP_012000008.1 flotillin family protein -
  FGL12_RS02485 (NCTC9124_00495) gndA 531365..532789 (+) 1425 WP_012000009.1 NADP-dependent phosphogluconate dehydrogenase -
  FGL12_RS02490 (NCTC9124_00496) covR 532802..533491 (+) 690 WP_012000010.1 response regulator transcription factor Regulator
  FGL12_RS02495 (NCTC9124_00497) - 533851..536043 (+) 2193 WP_012000011.1 PTS transporter subunit IIBC -
  FGL12_RS02500 (NCTC9124_00498) - 536061..536876 (+) 816 WP_012000012.1 endonuclease/exonuclease/phosphatase family protein -
  FGL12_RS02505 (NCTC9124_00499) - 537019..537435 (-) 417 WP_012000013.1 hypothetical protein -
  FGL12_RS02510 (NCTC9124_00500) nrdR 537614..538087 (+) 474 WP_012000014.1 transcriptional regulator NrdR -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26261.28 Da        Isoelectric Point: 5.1919

>NTDB_id=1127475 FGL12_RS02490 WP_012000010.1 532802..533491(+) (covR) [Streptococcus gordonii strain NCTC9124]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPAAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQKCSQLKVPTAYRNLRVDLKNHTVYRGEEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1127475 FGL12_RS02490 WP_012000010.1 532802..533491(+) (covR) [Streptococcus gordonii strain NCTC9124]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTTATCATGCTGGAATTACAAAAGGAAAGTTA
TCAAGTAGACCTAGCGGAAACAGGACAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTAAGTTTATTAAAACCAGCTGCAGTAATCATTGTAATG
GTGAGCCGAGAGGAGATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
TAGTGATCTGGTTGATAAAATATCTGCTATTTTTCGTGGTCGAGATTTTATTGATCAGAAATGTAGCCAGTTAAAAGTTC
CTACTGCTTATCGTAATTTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGAGAAGAAATTATTGCTTTGACGAGA
CGAGAGTACGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGCCGTGAGCAACTGTTAGACCGAGTGTGGAA
GTATGAAAGTGCATCTGAGACTAATATAGTGGATGTATATATTCGTTACCTCCGTAGTAAAATCGATCTTCCAGGACAAG
AAAGTTATATTAAAACCGTTCGTGGAATTGGTTATTCCATGCAGGGTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

51.77

98.69

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445

Multiple sequence alignment