Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   FGK97_RS06735 Genome accession   NZ_LR594037
Coordinates   1352988..1353677 (-) Length   229 a.a.
NCBI ID   WP_021001982.1    Uniprot ID   A0A1S1F9U0
Organism   Streptococcus anginosus strain NCTC11064     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1347988..1358677
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK97_RS06715 (NCTC11064_01384) nrdR 1348473..1348946 (-) 474 WP_003023591.1 transcriptional regulator NrdR -
  FGK97_RS06720 (NCTC11064_01385) - 1349112..1349708 (+) 597 WP_021001979.1 hypothetical protein -
  FGK97_RS06725 (NCTC11064_01386) - 1349755..1350570 (-) 816 WP_021001980.1 endonuclease/exonuclease/phosphatase family protein -
  FGK97_RS06730 (NCTC11064_01387) - 1350587..1352776 (-) 2190 WP_138099468.1 PTS transporter subunit IIBC -
  FGK97_RS06735 (NCTC11064_01388) covR 1352988..1353677 (-) 690 WP_021001982.1 DNA-binding response regulator Regulator
  FGK97_RS06740 (NCTC11064_01389) gndA 1353686..1355110 (-) 1425 WP_106079398.1 NADP-dependent phosphogluconate dehydrogenase -
  FGK97_RS06745 (NCTC11064_01390) - 1355409..1356032 (-) 624 WP_003023578.1 DNA alkylation repair protein -
  FGK97_RS06750 (NCTC11064_01391) - 1356083..1356619 (-) 537 WP_021001984.1 DUF177 domain-containing protein -
  FGK97_RS06755 (NCTC11064_01392) - 1356820..1357464 (+) 645 WP_282187185.1 XRE family transcriptional regulator -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26472.55 Da        Isoelectric Point: 6.2732

>NTDB_id=1127431 FGK97_RS06735 WP_021001982.1 1352988..1353677(-) (covR) [Streptococcus anginosus strain NCTC11064]
MAKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIVGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1127431 FGK97_RS06735 WP_021001982.1 1352988..1353677(-) (covR) [Streptococcus anginosus strain NCTC11064]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAATTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGTGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1S1F9U0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

100

0.454

Multiple sequence alignment