Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   FGK97_RS03780 Genome accession   NZ_LR594037
Coordinates   753450..754682 (+) Length   410 a.a.
NCBI ID   WP_021001590.1    Uniprot ID   A0AAP6BQ25
Organism   Streptococcus anginosus strain NCTC11064     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 751702..772928 753450..754682 within 0


Gene organization within MGE regions


Location: 751702..772928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK97_RS03765 (NCTC11064_00762) - 751702..752541 (+) 840 WP_021001588.1 thymidylate synthase -
  FGK97_RS03770 (NCTC11064_00763) - 752726..753238 (+) 513 WP_021001589.1 dihydrofolate reductase -
  FGK97_RS03775 (NCTC11064_00764) - 753238..753411 (+) 174 WP_003024903.1 hypothetical protein -
  FGK97_RS03780 (NCTC11064_00765) clpX 753450..754682 (+) 1233 WP_021001590.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  FGK97_RS03785 (NCTC11064_00766) yihA 754694..755281 (+) 588 WP_021001591.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  FGK97_RS03790 (NCTC11064_00767) - 755402..756109 (+) 708 WP_021001592.1 glucosaminidase domain-containing protein -
  FGK97_RS03795 (NCTC11064_00768) - 756282..758027 (+) 1746 WP_021001593.1 ABC transporter ATP-binding protein -
  FGK97_RS03800 (NCTC11064_00769) - 758008..759756 (+) 1749 WP_021001594.1 ABC transporter ATP-binding protein -
  FGK97_RS03805 (NCTC11064_00770) - 759777..761312 (-) 1536 WP_021001595.1 ATP-binding cassette domain-containing protein -
  FGK97_RS03810 (NCTC11064_00772) - 761735..762475 (-) 741 WP_003024883.1 amino acid ABC transporter ATP-binding protein -
  FGK97_RS03815 (NCTC11064_00773) - 762475..764658 (-) 2184 WP_021001596.1 ABC transporter substrate-binding protein/permease -
  FGK97_RS03820 (NCTC11064_00774) - 764821..765780 (+) 960 WP_003024878.1 CPBP family intramembrane glutamic endopeptidase -
  FGK97_RS03825 (NCTC11064_00775) uvrB 765871..767859 (+) 1989 WP_021001597.1 excinuclease ABC subunit UvrB -
  FGK97_RS03830 (NCTC11064_00776) - 767890..768435 (+) 546 WP_021001598.1 DUF1697 domain-containing protein -
  FGK97_RS03835 (NCTC11064_00777) - 768565..769308 (+) 744 WP_021001599.1 ABC transporter ATP-binding protein -
  FGK97_RS03840 (NCTC11064_00778) - 769298..770938 (+) 1641 WP_021001600.1 hypothetical protein -
  FGK97_RS03845 (NCTC11064_00779) hemW 771063..772193 (+) 1131 WP_138099385.1 radical SAM family heme chaperone HemW -
  FGK97_RS03850 (NCTC11064_00780) - 772197..772928 (+) 732 WP_003024864.1 acyl-[acyl-carrier-protein] thioesterase -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45669.16 Da        Isoelectric Point: 4.4240

>NTDB_id=1127421 FGK97_RS03780 WP_021001590.1 753450..754682(+) (clpX) [Streptococcus anginosus strain NCTC11064]
MPTNRTNEMMVYCSFCGKSQEEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLNILNHYVIGQDR
AKRALAVAVYNHYKRINFHDNHEDEEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDETGSYMQEIISEDIQKFGLIPELIGRLPVFAALEPLTVDDLVR
ILREPKNALVKQYQTLLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSQENVKLVRITKEAVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1127421 FGK97_RS03780 WP_021001590.1 753450..754682(+) (clpX) [Streptococcus anginosus strain NCTC11064]
ATGCCTACAAATCGTACGAATGAAATGATGGTTTATTGCTCTTTTTGTGGTAAAAGCCAAGAAGAAGTCCAAAAAATTAT
CGCAGGAAATAATGCCTTTATTTGTAATGAATGCGTGGAATTAGCGCAAGAAATCATCAGAGAGGAACTAGCAGAAGAAG
TACTAGCGGACTTGTCAGAAGTTCCAAAACCACAAGAACTACTCAATATTTTGAATCATTATGTGATTGGGCAAGACCGT
GCTAAGCGTGCTTTGGCTGTGGCTGTTTACAATCACTATAAACGCATCAATTTTCATGATAATCATGAAGATGAGGAAGA
TGTCGAATTGCAGAAATCCAATATTCTCATGATTGGGCCAACTGGTTCTGGCAAGACCTTTCTCGCTCAAACCTTGGCGA
AAAGTCTGAATGTTCCTTTTGCAATTGCAGACGCGACAGCTTTGACAGAAGCTGGGTATGTCGGAGAAGATGTTGAAAAT
ATTCTCTTGAAACTCTTGCAAGCAGCAGATTTCAATATTGAGCGTGCTGAACGTGGTATCATCTATGTAGATGAGATTGA
CAAAATTGCGAAGAAAAGCGAAAATGTCTCTATTACTCGCGATGTGTCTGGTGAAGGCGTTCAGCAAGCGCTTCTAAAAA
TCATTGAAGGAACTGTTGCCAGCGTACCTCCGCAAGGCGGCCGCAAGCACCCTCAACAAGAAATGATTCAAGTAGATACG
AAAAATATCCTCTTTATCGTTGGAGGAGCTTTCGACGGTATCGAAGAAATTGTTAAACAACGTCTAGGCGAAAAAATTAT
CGGTTTTGGTCAAAATAATAAAGCCATTGATGAAACTGGTTCTTATATGCAAGAAATCATCTCTGAAGATATTCAAAAAT
TTGGCTTGATTCCGGAATTGATTGGTCGTTTGCCTGTGTTTGCAGCGCTTGAGCCTTTGACAGTTGATGATTTGGTGCGA
ATCCTGCGCGAACCAAAGAATGCTTTAGTGAAGCAATATCAGACTCTCCTTTCTTATGACGATGTTAAACTAGAGTTTGA
TGATGATGCTCTTCAGGAAATTGCTAACAAGGCCATTGAACGCAAGACAGGTGCGCGTGGATTACGTTCAATCATCGAGG
AAACTATGATGGATGTCATGTTTGAAGTTCCAAGTCAAGAAAATGTGAAGCTGGTACGGATCACCAAGGAAGCAGTTGAC
GGAACGGATAAGCCGATTTTAGAAACAGCATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.829

100

0.868
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.458

98.049

0.573

Multiple sequence alignment