Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   LG36_RS07515 Genome accession   NZ_CP009472
Coordinates   1573552..1574181 (-) Length   209 a.a.
NCBI ID   WP_003131402.1    Uniprot ID   Q9CH48
Organism   Lactococcus lactis strain AI06     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1568552..1579181
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LG36_RS07490 (LG36_1430) - 1569478..1570722 (-) 1245 WP_038601409.1 FtsW/RodA/SpoVE family cell cycle protein -
  LG36_RS07495 (LG36_1431) - 1570944..1571549 (-) 606 WP_038601411.1 TVP38/TMEM64 family protein -
  LG36_RS07500 (LG36_1432) - 1571546..1571977 (-) 432 WP_038601413.1 CvfD/Ygs/GSP13 family RNA-binding post-transcriptional regulator -
  LG36_RS12245 (LG36_1433) - 1571979..1572569 (-) 591 WP_012897543.1 peptidylprolyl isomerase -
  LG36_RS12250 (LG36_1434) - 1572672..1573481 (-) 810 WP_038601415.1 Cof-type HAD-IIB family hydrolase -
  LG36_RS07515 (LG36_1435) vraR 1573552..1574181 (-) 630 WP_003131402.1 response regulator transcription factor Regulator
  LG36_RS07520 (LG36_1436) - 1574209..1575207 (-) 999 WP_038601417.1 sensor histidine kinase -
  LG36_RS07525 (LG36_1437) liaF 1575204..1575833 (-) 630 WP_012897539.1 cell wall-active antibiotics response protein LiaF -
  LG36_RS07530 (LG36_1438) rpsN 1575999..1576268 (-) 270 WP_038601419.1 30S ribosomal protein S14 -
  LG36_RS07535 (LG36_1439) - 1576366..1577664 (-) 1299 WP_052053855.1 LCP family protein -
  LG36_RS07540 (LG36_1440) - 1577695..1578894 (-) 1200 WP_012897536.1 FtsW/RodA/SpoVE family cell cycle protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23204.85 Da        Isoelectric Point: 5.3572

>NTDB_id=112733 LG36_RS07515 WP_003131402.1 1573552..1574181(-) (vraR) [Lactococcus lactis strain AI06]
MEKIKLLIVDDHQMVRLGLSSFMNIQPDIEVVGEAADGESGFLKTEMLDPDVILMDLVMDRLDGIGATQKILAKNPERKI
LILTSFIDDEKVFPALAAGAKGYILKTSQAADIASAIRKVANGEDVLSDAVKEKIAQQKHRKHELYDDLSKRELEVLKVL
ATGLSNQEIADELFISLKTVKTHVSNIFNKLEVSDRTQATIYAIQHHLV

Nucleotide


Download         Length: 630 bp        

>NTDB_id=112733 LG36_RS07515 WP_003131402.1 1573552..1574181(-) (vraR) [Lactococcus lactis strain AI06]
ATGGAAAAAATTAAACTTTTAATTGTTGATGACCACCAGATGGTGCGACTAGGTTTATCAAGTTTCATGAATATTCAACC
CGATATCGAAGTGGTTGGTGAAGCTGCCGATGGCGAGTCAGGTTTTTTAAAAACTGAAATGCTTGACCCTGATGTTATTC
TCATGGATTTAGTAATGGATCGACTTGATGGAATTGGAGCAACGCAAAAGATTTTAGCTAAAAATCCAGAACGAAAAATT
TTAATTCTAACGAGTTTTATTGATGACGAAAAAGTTTTTCCGGCTTTAGCTGCCGGAGCTAAAGGTTATATTCTTAAAAC
ATCACAAGCTGCTGATATCGCATCTGCAATCAGAAAAGTTGCCAATGGAGAAGATGTCCTTTCCGATGCTGTCAAGGAAA
AGATTGCTCAACAAAAACATCGAAAACATGAATTATATGATGATTTATCAAAAAGAGAATTAGAAGTATTAAAAGTACTT
GCGACGGGACTTTCTAATCAAGAAATTGCTGACGAACTTTTTATTAGTTTAAAAACAGTCAAAACTCATGTTTCTAATAT
TTTTAATAAGCTTGAAGTATCAGACCGAACTCAAGCAACAATTTATGCTATTCAACATCACTTAGTTTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-117)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CH48

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.565

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.416

Multiple sequence alignment