Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   FGL04_RS07390 Genome accession   NZ_LR594035
Coordinates   1431535..1433817 (+) Length   760 a.a.
NCBI ID   WP_138068740.1    Uniprot ID   -
Organism   Streptococcus pseudoporcinus strain NCTC5385     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 1426535..1438817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL04_RS07360 (NCTC5385_01603) - 1426570..1427439 (-) 870 WP_138068736.1 polyprenyl synthetase family protein -
  FGL04_RS07365 (NCTC5385_01604) - 1427439..1427657 (-) 219 WP_003084065.1 exodeoxyribonuclease VII small subunit -
  FGL04_RS07370 (NCTC5385_01605) xseA 1427632..1428975 (-) 1344 WP_138068737.1 exodeoxyribonuclease VII large subunit -
  FGL04_RS07375 (NCTC5385_01606) - 1429120..1429953 (-) 834 WP_138068738.1 NAD(P)H-hydrate dehydratase -
  FGL04_RS07380 (NCTC5385_01607) - 1429950..1430804 (-) 855 WP_138068739.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  FGL04_RS07385 (NCTC5385_01608) - 1431026..1431256 (-) 231 WP_077322042.1 DUF1797 family protein -
  FGL04_RS07390 (NCTC5385_01609) clpE 1431535..1433817 (+) 2283 WP_138068740.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FGL04_RS07395 (NCTC5385_01610) - 1433930..1434376 (+) 447 WP_138068741.1 NUDIX hydrolase -
  FGL04_RS07400 (NCTC5385_01611) - 1434426..1434728 (+) 303 WP_003084009.1 DUF1827 family protein -
  FGL04_RS07405 (NCTC5385_01612) ileS 1435120..1437921 (-) 2802 WP_138068742.1 isoleucine--tRNA ligase -

Sequence

Protein


Download         Length: 760 a.a.        Molecular weight: 84313.47 Da        Isoelectric Point: 5.2133

>NTDB_id=1127305 FGL04_RS07390 WP_138068740.1 1431535..1433817(+) (clpE) [Streptococcus pseudoporcinus strain NCTC5385]
MLCQNCKLNEASIHLYANVNGTQKQIDLCQNCYQIMKTDANNTILGGMRSKSQNQNDSLNPLFDDFFGDLNNFRAFGDLP
NTPPTQTGRQNGGGSGGGNNRNGQGAVPGQNTKREPGLLEEFGINVTDIARNGDIDPVIGRDEEIIRIIEILNRRTKNNP
VLIGEPGVGKTAVVEGLAQKIVDGSVPHKLQHKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRQDVILFIDEIHEI
VGAGTAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHV
KYSQDAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKLNLTLNFVDPKEIDKRLVEAENLKAQATRDEDFERAAYFRDQI
AKYKELQTQKVDDQDTPIITEKTIEAIVEQKTNIPVGDLKEKEQSQLVNLSDDLKAHVIGQDAAVDKIAKAIRRNRVGLG
SPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYS
LILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEASVGFGAARKGRTNSVMGELSNYFSP
EFMNRFDGIIEFQALSKEHLLQIVDLMLTDVNSRLAYNNIHLDVTDKVKEKLVDLGYDAKMGARPLRRTIQDHIEDAITD
YYLENPTEKNLKAMLSSNGNIVIKSAKKLDKAQSVSQQKD

Nucleotide


Download         Length: 2283 bp        

>NTDB_id=1127305 FGL04_RS07390 WP_138068740.1 1431535..1433817(+) (clpE) [Streptococcus pseudoporcinus strain NCTC5385]
ATGCTTTGTCAAAACTGTAAATTAAATGAAGCCTCTATTCACCTATACGCTAACGTGAATGGGACACAAAAGCAGATTGA
TCTTTGTCAAAACTGTTATCAAATTATGAAGACTGACGCAAATAACACGATTCTGGGTGGGATGCGTTCTAAATCCCAAA
ATCAAAATGATTCTTTGAATCCTTTATTTGACGATTTCTTTGGTGACCTCAACAACTTCAGAGCTTTTGGGGACTTGCCA
AATACACCCCCAACTCAGACTGGTAGACAAAATGGTGGAGGATCTGGCGGAGGCAACAATCGTAACGGCCAAGGAGCAGT
ACCTGGGCAAAATACCAAAAGAGAACCCGGTCTCCTTGAAGAGTTTGGTATTAACGTGACTGATATAGCAAGAAATGGTG
ATATTGATCCTGTCATTGGTCGCGATGAGGAAATCATTCGTATCATTGAGATTTTAAATCGACGAACCAAGAATAATCCT
GTCTTAATTGGTGAACCGGGTGTCGGTAAAACGGCAGTCGTAGAAGGTTTAGCCCAAAAAATCGTTGATGGTAGTGTTCC
TCATAAACTGCAACATAAAGAGGTGATTCGTTTGGACGTGGTTAGTCTAGTTCAGGGGACTGGTATTCGCGGACAATTTG
AAGAACGTATGCAAAAATTGATGGAAGAAATTCGTAATCGTCAAGATGTTATTCTCTTCATTGATGAGATTCATGAAATT
GTTGGTGCCGGTACTGCTGGGGATGGCAATATGGATGCTGGAAATATCTTAAAACCAGCCTTAGCTCGTGGGGAATTACA
GCTGGTTGGTGCAACAACACTCAACGAATACCGGATCATTGAAAAAGATGCTGCCTTAGAGCGTCGGATGCAACCTGTTA
AGGTCGATGAGCCTTCTGTGGAAGAAACCATTACTATTCTTAAAGGTATTCAAGCCAAATACGAAGATTATCATCATGTT
AAATACAGCCAAGATGCTATCGAAGCAGCTGCTAACTTATCGAACCGTTATATTCAAGATCGATTCTTACCGGATAAAGC
TATTGACTTGCTTGATGAAGCTGGATCAAAGCTGAATTTAACGCTTAACTTTGTTGACCCTAAAGAAATTGATAAACGAT
TAGTGGAAGCTGAAAATTTAAAAGCTCAAGCCACTCGTGATGAAGACTTTGAACGCGCAGCCTATTTCCGCGATCAAATT
GCTAAATACAAGGAGCTCCAAACTCAAAAGGTAGACGATCAAGATACTCCTATTATTACTGAAAAGACTATTGAAGCAAT
TGTTGAGCAAAAAACCAATATTCCTGTTGGTGATCTCAAAGAAAAAGAGCAATCTCAGTTAGTCAATCTTTCAGATGATT
TGAAAGCTCATGTAATTGGTCAAGATGCTGCTGTTGATAAAATTGCTAAGGCTATTCGTCGCAATCGTGTTGGTTTAGGT
AGCCCAAATCGACCGATTGGATCTTTCCTCTTTGTGGGCCCGACTGGGGTAGGGAAGACGGAACTCTCTAAACAATTAGC
TATTGAACTCTTCGGTTCAGCTGATAATATGATTCGTTTTGATATGTCTGAATATATGGAAAAGCACGCTGTTGCTAAGT
TAGTGGGAGCCCCTCCAGGATATGTCGGTTATGAAGAAGCCGGTCAATTAACAGAAAAAGTGAGACGAAATCCTTATTCA
CTGATATTATTGGACGAAGTTGAAAAAGCTCACCCTGACGTTATGCATATGTTCCTTCAAGTTTTAGATGATGGTCGGCT
AACTGATGGACAAGGACGGACAGTCAGCTTTAAAGATACTATTATTATCATGACATCAAATGCAGGTACTGGCAAAGCTG
AAGCCTCCGTTGGTTTTGGAGCTGCACGCAAAGGACGTACCAATTCTGTTATGGGAGAATTAAGCAATTACTTTAGCCCA
GAATTTATGAATCGTTTCGATGGCATTATTGAGTTCCAAGCATTAAGCAAAGAACATTTATTACAGATTGTTGATTTAAT
GTTGACTGATGTCAATAGCCGTTTAGCCTATAACAATATTCACCTTGACGTCACAGACAAGGTGAAGGAAAAATTAGTTG
ATCTCGGCTATGACGCTAAGATGGGGGCCCGTCCACTTAGAAGAACGATTCAAGATCATATCGAAGATGCCATTACAGAC
TATTATCTTGAAAATCCGACTGAGAAGAACTTAAAGGCTATGTTGTCAAGTAATGGTAATATAGTGATTAAAAGCGCCAA
AAAACTCGATAAAGCGCAATCTGTTTCTCAGCAAAAAGACTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(484-647)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(655-730)

ATPase family associated with various cellular activities (AAA) (AAA)

(161-279)

AAA lid domain (AAA_lid_9)

(299-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

84.574

98.947

0.837
  clpE Streptococcus pneumoniae Rx1

82.361

99.211

0.817
  clpE Streptococcus pneumoniae D39

82.361

99.211

0.817
  clpE Streptococcus pneumoniae R6

82.361

99.211

0.817
  clpE Streptococcus pneumoniae TIGR4

82.228

99.211

0.816
  clpC Lactococcus lactis subsp. cremoris KW2

76.087

96.842

0.737
  clpC Bacillus subtilis subsp. subtilis str. 168

51.493

88.158

0.454
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.937

82.895

0.397
  clpC Streptococcus pneumoniae Rx1

48.052

81.053

0.389
  clpC Streptococcus pneumoniae D39

48.052

81.053

0.389
  clpC Streptococcus pneumoniae TIGR4

47.89

81.053

0.388
  clpC Streptococcus thermophilus LMD-9

46.56

82.237

0.383
  clpC Streptococcus mutans UA159

47.154

80.921

0.382
  clpC Streptococcus thermophilus LMG 18311

46.24

82.237

0.38

Multiple sequence alignment