Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FGK99_RS07765 Genome accession   NZ_LR594033
Coordinates   1637504..1638826 (-) Length   440 a.a.
NCBI ID   WP_012516136.1    Uniprot ID   B4U4G3
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC4675     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1632504..1643826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK99_RS07755 (NCTC4675_01573) hpf 1636240..1636788 (-) 549 WP_012516134.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  FGK99_RS07760 (NCTC4675_01574) - 1636864..1637445 (-) 582 WP_012516135.1 ComF family protein -
  FGK99_RS07765 (NCTC4675_01575) comFA/cflA 1637504..1638826 (-) 1323 WP_012516136.1 DEAD/DEAH box helicase Machinery gene
  FGK99_RS07770 (NCTC4675_01576) - 1638882..1639523 (+) 642 WP_043026424.1 YigZ family protein -
  FGK99_RS07775 (NCTC4675_01577) cysK 1639644..1640570 (+) 927 WP_043041008.1 cysteine synthase A -
  FGK99_RS07780 (NCTC4675_01578) - 1640971..1641333 (-) 363 WP_012516140.1 S1 RNA-binding domain-containing protein -
  FGK99_RS07785 (NCTC4675_01579) - 1641333..1642733 (-) 1401 WP_138119678.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FGK99_RS07790 (NCTC4675_01580) - 1642766..1643407 (-) 642 WP_041785672.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 49868.96 Da        Isoelectric Point: 9.6948

>NTDB_id=1127192 FGK99_RS07765 WP_012516136.1 1637504..1638826(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
MENIENYYGRLFPEGKCPKAVSAWACSLQSMIAKKGTLYCQRCGSLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPP
ASFPKGHYLRWQGQLTTYQAAVSHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVNKGGWVCIASPRVDVCIELEKR
LSRDFSCQVCLMHAESEVYHRSPIIVATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQLNHAAHQAAKADAVTVYLTATST
RDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFSLLEAINRGKLPRRFITLVKKQRATGYPLLIFFPIIELAEQCCQL
LQKYFPKETIAHASSQSSNRMAIIEQFRQGQITILISTTILERGVTFPTVDVFVLLANHRLYTSSSLIQISGRVGRSLER
PEGQVLFFHDGISQAMLKAVREIKDMNQKGYQNELSTLPQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1127192 FGK99_RS07765 WP_012516136.1 1637504..1638826(-) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain NCTC4675]
ATGGAGAATATCGAAAATTACTATGGACGCCTTTTCCCTGAAGGGAAATGCCCAAAGGCTGTTTCTGCCTGGGCTTGCAG
CTTACAAAGCATGATCGCTAAAAAAGGAACGTTATACTGCCAACGCTGTGGCAGTTTAATTGAGAAGGCTCATCAGCTGC
CTAGCGGTGCTTACTACTGTAGAGCCTGTCTTGTTTTTGGTCGAAACCAATCTGATCGCCCCTTGCTCTATTTTCCACCG
GCTTCTTTTCCAAAGGGACATTATCTGAGGTGGCAAGGACAGCTCACGACATATCAGGCAGCTGTCTCTCATCAGCTTAC
TAACCATGTTAAGCTCAAGCAAGACACCTTAGTTCATGCGGTTACTGGTGCTGGCAAAACAGAGATGATGTATGAAGCTA
TTGCAGCAGTTGTTAATAAGGGTGGCTGGGTCTGCATTGCTAGTCCACGAGTTGATGTCTGCATAGAGCTTGAAAAACGA
CTATCGCGGGACTTTTCCTGTCAAGTCTGCCTTATGCATGCTGAGTCAGAGGTTTATCATAGAAGTCCCATTATCGTTGC
CACAACACATCAATTGATGACCTTTTACCATGCTTTTGATCTGCTCATTATTGACGAAGTAGATGCCTTCCCTTTTGTCA
ATAATCGTCAATTAAACCATGCTGCTCATCAGGCTGCAAAAGCAGATGCAGTGACAGTATACCTAACAGCAACCTCTACA
AGAGATTTAGAGCGCAAGGTCAAGCAAAAAGAGCTTGTCAAATTGACGTTGGCAAGAAGATTCCATGGCAAGCCTTTAGT
TGTTCCAAAGTATCAAAGATTATTCTCCCTTTTAGAGGCTATCAATCGCGGGAAATTGCCTAGAAGGTTCATCACCCTAG
TCAAAAAACAAAGGGCAACCGGCTATCCTCTTTTAATCTTTTTTCCGATTATTGAGCTGGCTGAGCAATGCTGTCAGCTG
TTACAAAAGTATTTTCCTAAGGAAACTATTGCTCATGCTTCCAGTCAGTCATCAAATCGAATGGCTATCATTGAGCAATT
CAGACAAGGACAAATCACTATACTTATATCAACAACCATTTTGGAAAGAGGTGTGACTTTTCCAACCGTAGATGTCTTTG
TCTTATTAGCCAATCATCGCCTTTACACAAGCAGCAGTCTTATTCAAATTTCAGGTCGCGTTGGGCGCTCTTTGGAAAGA
CCTGAAGGACAGGTGCTATTTTTTCATGATGGTATTAGCCAGGCTATGCTCAAGGCAGTGCGGGAGATAAAGGACATGAA
TCAAAAAGGGTATCAAAATGAACTGTCTACTCTGCCACAATAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(288-396)

DEAD/DEAH box helicase (DEAD)

(98-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B4U4G3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis SK321

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae D39

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae R6

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae Rx1

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae TIGR4

53.176

96.591

0.514
  comFA/cflA Streptococcus mitis NCTC 12261

52.941

96.591

0.511
  comFA Lactococcus lactis subsp. cremoris KW2

48.214

89.091

0.43

Multiple sequence alignment