Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FGK91_RS06825 Genome accession   NZ_LR590483
Coordinates   1316581..1317906 (-) Length   441 a.a.
NCBI ID   WP_115224631.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8318     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1311581..1322906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGK91_RS06815 (NCTC8318_01361) raiA 1315316..1315864 (-) 549 WP_002988974.1 ribosome-associated translation inhibitor RaiA -
  FGK91_RS06820 (NCTC8318_01362) - 1315944..1316609 (-) 666 WP_002983685.1 ComF family protein -
  FGK91_RS06825 (NCTC8318_01363) comFA/cflA 1316581..1317906 (-) 1326 WP_115224631.1 DEAD/DEAH box helicase Machinery gene
  FGK91_RS06830 (NCTC8318_01364) - 1317962..1318594 (+) 633 WP_032465870.1 YigZ family protein -
  FGK91_RS06835 (NCTC8318_01365) cysK 1318722..1319663 (+) 942 WP_023079244.1 cysteine synthase A -
  FGK91_RS06840 (NCTC8318_01366) - 1319681..1320058 (-) 378 WP_002983674.1 S1 RNA-binding domain-containing protein -
  FGK91_RS06845 (NCTC8318_01367) - 1320058..1321458 (-) 1401 WP_023079249.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FGK91_RS06850 (NCTC8318_01368) - 1321495..1322136 (-) 642 WP_023079253.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49772.28 Da        Isoelectric Point: 10.0535

>NTDB_id=1127057 FGK91_RS06825 WP_115224631.1 1316581..1317906(-) (comFA/cflA) [Streptococcus pyogenes strain NCTC8318]
MESIENSYGRLLLESQLPDSAKQLAQPLKSVVILRGKMICQRSHYQLDEEARLPSGAYYCRFCLVFGRNQSDKLLYAIPP
MHFPKGNYLVWGGQLTAYQEMISQQLLINMQNQKTTLVHAVTGAGKTEMIYAAIEAVINTGGWVCIASPRVDVCVEVATR
LSQAFSCSICLMHAESLPYQRAPIIVATTHQLLKFHKAFDLLIIDEVDAFPFVNNIQLHYAASQALKEGGAKILLTATST
RTLERKVNKGEVVKLTLARRFHNRPLVIPKFIRSFNLFKMIHRQKLPPKILKYLKKQRKTGYPLLIFLPTIIMAESVTAI
LKDLLPAEQIACVSSQSQNRKEDITAFRQGKKTILITTTILERGVTFPQIDIFVLGSHHRVYSSQSLVQIAGRVGRSIDR
PDGTLYFFHEGISKAMLLARKEIKEMNYKGYSHDLSTMSTN

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1127057 FGK91_RS06825 WP_115224631.1 1316581..1317906(-) (comFA/cflA) [Streptococcus pyogenes strain NCTC8318]
ATGGAGTCTATTGAAAATAGTTATGGACGGTTGTTGCTAGAAAGCCAGTTACCAGATTCAGCAAAGCAGCTTGCTCAACC
TTTAAAAAGTGTAGTAATATTGAGAGGAAAAATGATTTGTCAACGTTCTCACTATCAGCTTGATGAAGAAGCACGATTGC
CAAGTGGAGCCTATTATTGCCGATTTTGTCTTGTCTTTGGACGAAATCAATCAGATAAATTGCTCTATGCTATCCCACCT
ATGCATTTTCCAAAAGGTAATTATCTGGTTTGGGGCGGTCAACTAACTGCTTATCAAGAGATGATTTCCCAACAATTATT
AATCAATATGCAAAATCAAAAAACAACATTAGTTCATGCTGTAACTGGTGCAGGAAAAACAGAAATGATTTATGCTGCGA
TTGAGGCGGTAATTAACACAGGTGGCTGGGTTTGCATTGCCAGCCCAAGAGTAGATGTTTGTGTAGAGGTGGCTACTCGT
TTATCCCAAGCCTTCTCCTGCAGCATCTGTTTAATGCACGCAGAGTCTCTTCCTTATCAAAGAGCTCCTATTATAGTAGC
CACAACGCATCAGCTGCTAAAATTTCACAAGGCTTTTGATCTCTTAATTATTGATGAAGTAGACGCATTCCCTTTTGTAA
ATAATATTCAACTTCATTATGCTGCAAGTCAGGCTTTAAAAGAAGGTGGCGCAAAGATTTTATTAACTGCAACTTCAACT
AGAACTTTAGAAAGAAAGGTAAACAAGGGAGAAGTAGTCAAGCTGACATTGGCGAGACGCTTTCATAATAGGCCATTAGT
TATTCCAAAATTTATAAGAAGTTTTAATCTATTTAAAATGATACATCGGCAAAAACTTCCTCCTAAAATTTTAAAATACT
TAAAAAAACAAAGAAAAACAGGCTATCCCCTTTTAATTTTTCTACCCACTATTATAATGGCAGAATCTGTTACAGCAATC
TTAAAAGACTTATTGCCCGCCGAACAAATAGCTTGTGTTTCTAGTCAATCACAAAACAGGAAAGAAGATATCACAGCTTT
TCGTCAAGGGAAAAAAACGATTTTAATTACAACAACAATTTTAGAAAGGGGTGTGACATTTCCCCAAATTGATATTTTTG
TTCTTGGGTCTCATCATCGTGTCTATAGTTCCCAAAGTCTTGTTCAAATTGCTGGACGAGTTGGAAGATCTATAGACAGA
CCAGACGGAACGTTATATTTCTTTCATGAAGGTATCAGTAAAGCAATGCTACTAGCAAGAAAAGAGATTAAAGAAATGAA
TTATAAAGGGTATTCGCATGATCTGTCTACTATGTCAACAAATTAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-396)

DEAD/DEAH box helicase (DEAD)

(98-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.461

95.011

0.508
  comFA/cflA Streptococcus pneumoniae D39

53.461

95.011

0.508
  comFA/cflA Streptococcus pneumoniae R6

53.461

95.011

0.508
  comFA/cflA Streptococcus pneumoniae TIGR4

53.461

95.011

0.508
  comFA/cflA Streptococcus mitis NCTC 12261

52.133

95.692

0.499
  comFA/cflA Streptococcus mitis SK321

51.422

95.692

0.492
  comFA Lactococcus lactis subsp. cremoris KW2

46.97

89.796

0.422
  comFA Latilactobacillus sakei subsp. sakei 23K

38.851

98.639

0.383

Multiple sequence alignment