Detailed information NTG1127047

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: FGK91_RS03680
• Genome accession: NZ_LR590483
• Coordinates: 704591..705820 (+)
• Length: 409 a.a.
• NCBI ID: WP_146710348.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8318
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 699591..710820

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK91_RS03655 (NCTC8318_00722)	-	700207..701484 (-)	1278	WP_002984963.1	hydroxymethylglutaryl-CoA reductase, degradative	-
FGK91_RS03660 (NCTC8318_00723)	-	701471..702646 (-)	1176	WP_023079103.1	hydroxymethylglutaryl-CoA synthase	-
FGK91_RS03665 (NCTC8318_00724)	-	702855..703694 (+)	840	WP_011017679.1	thymidylate synthase	-
FGK91_RS03670 (NCTC8318_00725)	-	703774..704271 (+)	498	WP_002984955.1	dihydrofolate reductase	-
FGK91_RS03680 (NCTC8318_00727)	clpX	704591..705820 (+)	1230	WP_146710348.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
FGK91_RS03685 (NCTC8318_00728)	yihA	705830..706429 (+)	600	WP_023079094.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
FGK91_RS03690 (NCTC8318_00729)	-	706577..707320 (+)	744	WP_002984942.1	hypothetical protein	-
FGK91_RS03695 (NCTC8318_00730)	-	707378..709477 (-)	2100	WP_023079078.1	ATP-dependent Clp protease ATP-binding subunit	-
FGK91_RS03700 (NCTC8318_00731)	rpiA	709855..710538 (+)	684	WP_002994002.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45039.48 Da
• Isoelectric Point: 4.5775

>NTDB_id=1127047 FGK91_RS03680 WP_146710348.1 704591..705820(+) (clpX) [Streptococcus pyogenes strain NCTC8318]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDFLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=1127047 FGK91_RS03680 WP_146710348.1 704591..705820(+) (clpX) [Streptococcus pyogenes strain NCTC8318]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATTTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CAATGCTTGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.998	100	0.89
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575