Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   FGL10_RS05375 Genome accession   NZ_LR590477
Coordinates   1024342..1025859 (+) Length   505 a.a.
NCBI ID   WP_036475132.1    Uniprot ID   -
Organism   Neisseria lactamica strain NCTC10617     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1019342..1030859
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL10_RS12035 - 1019355..1019588 (-) 234 WP_147280912.1 hypothetical protein -
  FGL10_RS05360 (NCTC10617_00941) - 1019604..1020287 (-) 684 WP_003709391.1 2,3-diphosphoglycerate-dependent phosphoglycerate mutase -
  FGL10_RS05365 (NCTC10617_00942) parC 1020434..1022737 (+) 2304 WP_003709389.1 DNA topoisomerase IV subunit A -
  FGL10_RS05370 (NCTC10617_00943) - 1022757..1024349 (+) 1593 WP_003709387.1 ATP-binding protein -
  FGL10_RS05375 (NCTC10617_00944) pilR 1024342..1025859 (+) 1518 WP_036475132.1 sigma-54-dependent transcriptional regulator Regulator
  FGL10_RS05380 (NCTC10617_00945) - 1025964..1026716 (+) 753 WP_003709381.1 class I SAM-dependent methyltransferase -
  FGL10_RS05390 (NCTC10617_00946) - 1027307..1027513 (-) 207 WP_002212781.1 DUF2788 domain-containing protein -
  FGL10_RS05395 (NCTC10617_00947) metZ 1027599..1028768 (-) 1170 WP_036475313.1 O-succinylhomoserine sulfhydrylase -
  FGL10_RS05400 (NCTC10617_00948) - 1028913..1029683 (-) 771 WP_003709371.1 hypothetical protein -
  FGL10_RS05405 (NCTC10617_00949) - 1029784..1030035 (+) 252 WP_002245658.1 NGO1151 family protein -

Sequence

Protein


Download         Length: 505 a.a.        Molecular weight: 56255.31 Da        Isoelectric Point: 6.1527

>NTDB_id=1126933 FGL10_RS05375 WP_036475132.1 1024342..1025859(+) (pilR) [Neisseria lactamica strain NCTC10617]
MTELQHPVLVVDDETDILDLMEMTLMKMGLRVHTASGVTEAKNKLDSQRYSLVLTDMRMPDGSGLEVVQHINSRLLDTPV
AVITAFGNADQAQEALRCGAFDYIQKPITLARLRSLVKSAISVSENQNKIPEPPVRTASPVSSPMPSEAPEPANAIPAAP
PVSSALPYAEPDMPRLLGSSPQMVEIRHLIRRLASGKVPVYISGESGTGKEQAARTIHELSDRADKPFVAVNCGAIPENL
MESEFFGYRKGSFTGADKDHDGFFRHADGGTLFLDEVADLPLSMQVKLLRAIQEKAVRRIGDTAEQPVDVRIVCATHKNL
EALVGSGAFRQDLYYRLNVVSLNMPSLREMREDLKLLIPYLLYKHSRNNRPYTLSPAAQQMLLNYSYPGNFRELENILER
AVALCVGHTVQIDDLQIQDVRHKPVRTETAERAADTLPSETAAAPSRVLPFDPDTMQIQDYLDQIERDIIEQTLKQTEGN
RTQAAKRLGISFRSMRYRMERLNIC

Nucleotide


Download         Length: 1518 bp        

>NTDB_id=1126933 FGL10_RS05375 WP_036475132.1 1024342..1025859(+) (pilR) [Neisseria lactamica strain NCTC10617]
ATGACTGAACTGCAACATCCCGTCCTCGTCGTCGATGACGAAACCGACATTCTCGACCTGATGGAAATGACCCTGATGAA
AATGGGCTTGCGCGTCCATACCGCGTCAGGCGTTACCGAAGCCAAAAACAAGCTCGACAGCCAACGCTATTCGCTCGTCC
TGACCGATATGCGTATGCCCGACGGCTCGGGGCTTGAAGTCGTCCAACACATCAACAGCCGCCTGCTCGATACGCCGGTT
GCCGTCATCACCGCCTTCGGCAATGCCGATCAGGCGCAAGAGGCCCTGCGTTGCGGCGCGTTCGACTACATCCAAAAGCC
GATTACCCTCGCCCGGCTGCGTTCCCTCGTCAAATCGGCAATTTCCGTTTCCGAAAACCAAAACAAAATTCCCGAACCGC
CCGTTCGGACGGCATCCCCCGTTTCTTCCCCAATGCCGTCTGAAGCCCCGGAACCTGCAAACGCGATACCGGCGGCACCG
CCCGTTTCCTCCGCCCTTCCCTATGCGGAACCCGATATGCCCCGCCTGCTCGGCAGCTCTCCGCAGATGGTCGAAATCCG
CCACCTCATCCGCCGCCTCGCGTCCGGCAAAGTACCCGTCTATATTTCCGGCGAATCCGGTACAGGTAAGGAACAGGCGG
CGCGCACCATACACGAACTGTCCGACCGCGCGGACAAACCCTTTGTCGCCGTCAACTGCGGTGCGATTCCCGAAAATCTG
ATGGAAAGCGAATTTTTCGGCTACCGCAAAGGCAGTTTTACCGGCGCCGACAAAGACCACGACGGCTTTTTCCGCCACGC
CGACGGCGGCACTTTGTTTTTGGACGAAGTCGCCGACCTGCCCCTTTCCATGCAGGTCAAACTCTTGCGCGCGATTCAAG
AAAAAGCCGTGCGCCGCATCGGCGATACCGCCGAGCAGCCCGTCGATGTCCGCATCGTCTGCGCCACCCACAAAAACCTC
GAAGCCCTTGTCGGAAGCGGCGCATTCCGCCAAGACCTGTATTACCGCCTCAATGTCGTCAGCCTCAATATGCCGTCCCT
GCGTGAAATGCGCGAAGATTTGAAGCTGCTCATCCCCTACCTCCTGTACAAACACAGCCGCAACAACCGGCCTTACACAC
TCTCCCCCGCCGCGCAACAGATGCTCCTGAATTACAGCTATCCGGGCAATTTCCGCGAACTGGAAAACATCCTCGAACGC
GCCGTCGCCCTGTGCGTCGGGCATACCGTGCAAATCGACGACCTGCAAATCCAAGATGTGCGCCACAAGCCCGTCCGGAC
GGAAACCGCCGAGCGCGCCGCCGATACCTTGCCGTCTGAAACAGCCGCCGCACCGTCCCGCGTCCTGCCGTTCGACCCCG
ATACCATGCAGATACAGGACTATCTCGACCAAATCGAACGCGACATCATCGAACAAACCCTCAAACAAACCGAAGGCAAC
CGCACGCAGGCTGCTAAACGCTTGGGCATCAGCTTCCGTTCGATGCGCTACCGTATGGAACGCCTCAACATCTGCTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(8-117)

Bacterial regulatory protein, Fis family (HTH_8)

(462-501)

Sigma-54 interaction domain (Sigma54_activat)

(176-342)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

48.805

99.406

0.485
  pilR Acinetobacter baumannii strain A118

41.339

100

0.416

Multiple sequence alignment