Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   E0F40_RS05855 Genome accession   NZ_LR216065
Coordinates   1104003..1104812 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1099003..1109812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F40_RS05835 (SAMEA3714487_01113) - 1101469..1102455 (+) 987 WP_000204727.1 L-lactate dehydrogenase -
  E0F40_RS05840 (SAMEA3714487_01114) - 1102715..1103367 (-) 653 Protein_1112 potassium channel family protein -
  E0F40_RS05845 (SAMEA3714487_01115) - 1103414..1103668 (-) 255 WP_001812387.1 type II toxin-antitoxin system RelE family toxin -
  E0F40_RS05850 (SAMEA3714487_01116) relB 1103670..1103912 (-) 243 WP_000208080.1 type II toxin-antitoxin system RelB family antitoxin -
  E0F40_RS05855 (SAMEA3714487_01117) vicX 1104003..1104812 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  E0F40_RS05860 (SAMEA3714487_01118) micB 1104814..1106163 (-) 1350 WP_000886209.1 cell wall metabolism sensor histidine kinase VicK Regulator
  E0F40_RS05865 (SAMEA3714487_01119) micA 1106156..1106860 (-) 705 WP_000722076.1 response regulator YycF Regulator
  E0F40_RS05870 (SAMEA3714487_01120) mutY 1106915..1108090 (-) 1176 WP_000886147.1 A/G-specific adenine glycosylase -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=1126339 E0F40_RS05855 WP_001289493.1 1104003..1104812(-) (vicX) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=1126339 E0F40_RS05855 WP_001289493.1 1104003..1104812(-) (vicX) [Streptococcus pneumoniae strain GPSC18 substr. ST13 isolate 55896440-41bd-11e5-998e-3c4a9275d6c6]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTTTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGCTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
ACTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment