Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   E0F31_RS01885 Genome accession   NZ_LR216064
Coordinates   343280..343969 (+) Length   229 a.a.
NCBI ID   WP_054363083.1    Uniprot ID   A0A4J2E855
Organism   Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 338280..348969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F31_RS01860 (SAMEA3714520_00349) gpsB 338389..338718 (+) 330 WP_000146522.1 cell division regulator GpsB -
  E0F31_RS01870 (SAMEA3714520_00350) - 339204..340361 (+) 1158 WP_000711402.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  E0F31_RS01875 (SAMEA3714520_00351) mapZ 340374..341768 (+) 1395 WP_000039286.1 cell division site-positioning protein MapZ -
  E0F31_RS01880 (SAMEA3714520_00352) gndA 341844..343268 (+) 1425 WP_000158798.1 NADP-dependent phosphogluconate dehydrogenase -
  E0F31_RS01885 (SAMEA3714520_00353) covR 343280..343969 (+) 690 WP_054363083.1 response regulator transcription factor Regulator
  E0F31_RS01890 (SAMEA3714520_00354) cbpC 344067..345032 (+) 966 WP_000771105.1 choline-binding protein CbpC -
  E0F31_RS01895 (SAMEA3714520_00355) cbpJ 345051..346049 (+) 999 WP_000771134.1 choline-binding protein CbpJ -
  E0F31_RS01900 (SAMEA3714520_00356) - 346167..347399 (-) 1233 WP_000765664.1 MFS transporter -
  E0F31_RS01905 (SAMEA3714520_00357) - 347558..348028 (-) 471 WP_001810352.1 lanthionine synthetase LanC family protein -
  E0F31_RS01910 - 347928..348266 (-) 339 WP_001820155.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26896.17 Da        Isoelectric Point: 6.9836

>NTDB_id=1126247 E0F31_RS01885 WP_054363083.1 343280..343969(+) (covR) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLIKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1126247 E0F31_RS01885 WP_054363083.1 343280..343969(+) (covR) [Streptococcus pneumoniae strain GPSC13 substr. ST473 isolate 569492b0-41bd-11e5-998e-3c4a9275d6c6]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATAAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4J2E855

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

100

0.467

Multiple sequence alignment