Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   E0F39_RS10115 Genome accession   NZ_LR216060
Coordinates   1869327..1869947 (-) Length   206 a.a.
NCBI ID   WP_001864529.1    Uniprot ID   A0A0T8T116
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1864327..1874947
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS10090 (SAMEA3713867_01905) recA 1864704..1865870 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  E0F39_RS10095 (SAMEA3713867_01906) cinA 1865925..1867181 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  E0F39_RS10100 (SAMEA3713867_01907) brpA 1867266..1868282 (-) 1017 WP_000239284.1 biofilm formation/cell division transcriptional regulator BrpA -
  E0F39_RS10105 (SAMEA3713867_01908) - 1868290..1868808 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  E0F39_RS10110 (SAMEA3713867_01909) tsaE 1868798..1869241 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  E0F39_RS10115 (SAMEA3713867_01910) comM 1869327..1869947 (-) 621 WP_001864529.1 hypothetical protein Regulator
  E0F39_RS10125 (SAMEA3713867_01911) - 1870330..1871193 (-) 864 WP_130886889.1 helix-turn-helix domain-containing protein -
  E0F39_RS13075 (SAMEA3713867_01912) - 1871382..1871552 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  E0F39_RS10135 (SAMEA3713867_01913) - 1871680..1873695 (+) 2016 WP_001864530.1 DUF1430 domain-containing protein -
  E0F39_RS10140 (SAMEA3713867_01914) - 1873697..1874329 (+) 633 WP_000571422.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23566.74 Da        Isoelectric Point: 10.1254

>NTDB_id=1126210 E0F39_RS10115 WP_001864529.1 1869327..1869947(-) (comM) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
ISLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1126210 E0F39_RS10115 WP_001864529.1 1869327..1869947(-) (comM) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCTTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
ATCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8T116

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment