Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   E0F39_RS02070 Genome accession   NZ_LR216060
Coordinates   371363..372052 (+) Length   229 a.a.
NCBI ID   WP_000518008.1    Uniprot ID   A0A0B7KUQ5
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 366363..377052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS02045 (SAMEA3713867_00380) gpsB 366472..366801 (+) 330 WP_000146520.1 cell division regulator GpsB -
  E0F39_RS02055 (SAMEA3713867_00381) - 367287..368444 (+) 1158 WP_001864872.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  E0F39_RS02060 (SAMEA3713867_00382) mapZ 368457..369851 (+) 1395 WP_000039306.1 cell division site-positioning protein MapZ -
  E0F39_RS02065 (SAMEA3713867_00383) gndA 369927..371351 (+) 1425 WP_000158793.1 NADP-dependent phosphogluconate dehydrogenase -
  E0F39_RS02070 (SAMEA3713867_00384) covR 371363..372052 (+) 690 WP_000518008.1 response regulator transcription factor Regulator
  E0F39_RS02075 (SAMEA3713867_00385) cbpC 372151..373173 (+) 1023 WP_000771050.1 choline-binding protein CbpC -
  E0F39_RS02080 (SAMEA3713867_00386) cbpJ 373192..374190 (+) 999 WP_000771135.1 choline-binding protein CbpJ -
  E0F39_RS02085 (SAMEA3713867_00387) - 374308..375540 (-) 1233 WP_000765691.1 MFS transporter -
  E0F39_RS02090 (SAMEA3713867_00388) - 375583..376458 (-) 876 WP_230400225.1 lanthionine synthetase LanC family protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26914.21 Da        Isoelectric Point: 6.9836

>NTDB_id=1126172 E0F39_RS02070 WP_000518008.1 371363..372052(+) (covR) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1126172 E0F39_RS02070 WP_000518008.1 371363..372052(+) (covR) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTTCAGACAGACTATGATTTGATTTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATCTATAAGCCAGTCTTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGTAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7KUQ5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.522

100

0.467

Multiple sequence alignment