Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   E0F32_RS09405 Genome accession   NZ_LR216050
Coordinates   1740157..1740777 (-) Length   206 a.a.
NCBI ID   WP_000839909.1    Uniprot ID   A0A098Z2X2
Organism   Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1735157..1745777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F32_RS09380 (SAMEA3431333_01761) recA 1735534..1736700 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  E0F32_RS09385 (SAMEA3431333_01762) cinA 1736755..1738011 (-) 1257 WP_000642706.1 competence/damage-inducible protein A Machinery gene
  E0F32_RS09390 (SAMEA3431333_01763) brpA 1738096..1739112 (-) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  E0F32_RS09395 (SAMEA3431333_01764) - 1739120..1739638 (-) 519 WP_024477661.1 GNAT family N-acetyltransferase -
  E0F32_RS09400 (SAMEA3431333_01765) tsaE 1739628..1740071 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  E0F32_RS09405 (SAMEA3431333_01766) comM 1740157..1740777 (-) 621 WP_000839909.1 hypothetical protein Regulator
  E0F32_RS09415 (SAMEA3431333_01767) - 1741160..1742023 (-) 864 WP_024477662.1 helix-turn-helix domain-containing protein -
  E0F32_RS11615 (SAMEA3431333_01768) - 1742212..1742382 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  E0F32_RS09425 (SAMEA3431333_01769) - 1742832..1744847 (+) 2016 WP_000732385.1 DUF1430 domain-containing protein -
  E0F32_RS09430 (SAMEA3431333_01770) - 1744849..1745481 (+) 633 WP_000571415.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23540.66 Da        Isoelectric Point: 10.1254

>NTDB_id=1126136 E0F32_RS09405 WP_000839909.1 1740157..1740777(-) (comM) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1126136 E0F32_RS09405 WP_000839909.1 1740157..1740777(-) (comM) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATACTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A098Z2X2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

99.515

100

0.995
  comM Streptococcus pneumoniae R6

99.515

100

0.995
  comM Streptococcus pneumoniae TIGR4

99.515

100

0.995
  comM Streptococcus mitis NCTC 12261

38.462

94.66

0.364
  comM Streptococcus mitis SK321

38.462

94.66

0.364

Multiple sequence alignment