Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   E0F32_RS07655 Genome accession   NZ_LR216050
Coordinates   1430282..1431514 (-) Length   410 a.a.
NCBI ID   WP_000106349.1    Uniprot ID   A0AA95D8Q6
Organism   Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1425282..1436514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F32_RS07625 (SAMEA3431333_01434) - 1425469..1426437 (+) 969 WP_000081008.1 NAD(P)/FAD-dependent oxidoreductase -
  E0F32_RS07630 (SAMEA3431333_01435) whiA 1426471..1427382 (-) 912 WP_000011306.1 DNA-binding protein WhiA -
  E0F32_RS07635 (SAMEA3431333_01436) - 1427379..1428356 (-) 978 WP_001231086.1 YvcK family protein -
  E0F32_RS07640 (SAMEA3431333_01437) rapZ 1428353..1429243 (-) 891 WP_000163035.1 RNase adapter RapZ -
  E0F32_RS07645 (SAMEA3431333_01438) - 1429295..1429675 (-) 381 WP_001140412.1 RidA family protein -
  E0F32_RS07650 (SAMEA3431333_01439) yihA 1429686..1430273 (-) 588 WP_000422599.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  E0F32_RS07655 (SAMEA3431333_01440) clpX 1430282..1431514 (-) 1233 WP_000106349.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  E0F32_RS11600 (SAMEA3431333_01441) - 1431546..1431716 (-) 171 WP_000442275.1 hypothetical protein -
  E0F32_RS07665 (SAMEA3431333_01442) - 1431716..1432222 (-) 507 WP_044813104.1 dihydrofolate reductase -
  E0F32_RS07670 (SAMEA3431333_01443) - 1432352..1432870 (-) 519 WP_000229874.1 Dps family protein -
  E0F32_RS07675 (SAMEA3431333_01444) lytC 1433366..1434871 (-) 1506 WP_078132790.1 choline binding-anchored murein hydrolase LytC -
  E0F32_RS07680 (SAMEA3431333_01445) tpiA 1434909..1435667 (-) 759 WP_000087897.1 triose-phosphate isomerase -
  E0F32_RS07685 (SAMEA3431333_01446) - 1435765..1436442 (-) 678 WP_000221612.1 DnaD domain-containing protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45816.38 Da        Isoelectric Point: 4.4550

>NTDB_id=1126120 E0F32_RS07655 WP_000106349.1 1430282..1431514(-) (clpX) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILNHYVIGQDR
AKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDT
KNILFIVGGAFDGIEEIVKQRMGEKVIGFGQNNKAIDENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVR
ILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLVRITKETVD
GTDKPILETA

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1126120 E0F32_RS07655 WP_000106349.1 1430282..1431514(-) (clpX) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGTCTACAAATAGAAAAAATGATATGATGGTTTATTGCTCATTTTGTGGCAAAAACCAAGAAGAAGTACAAAAAATAAT
TGCTGGCAACAATGCTTTTATTTGTAATGAATGCGTGGAGTTAGCTCAGGAAATCATTCGAGAAGAATTGGTTGAGGAAG
TCTTGGCAGACTTGTCTGAGGTGCCAAAACCAATTGAACTCCTCCATATCTTGAACCACTATGTAATTGGTCAAGATCGT
GCCAAGCGTGCCTTGGCAGTGGCGGTTTATAACCACTACAAACGCATCAATTTCCACGATACACGCGAAGAGTCAGAAGA
TGTGGATTTGCAGAAGTCAAACATTTTGATGATTGGCCCAACTGGTTCAGGGAAAACTTTCCTTGCCCAGACCTTGGCTA
AGAGCTTGAATGTACCTTTTGCTATTGCGGATGCGACAGCTCTGACGGAGGCTGGTTATGTGGGTGAGGATGTGGAAAAT
ATCCTCCTCAAACTCTTGCAGGTTGCTGACTTTAACATCGAACGTGCAGAGCGTGGCATTATCTATGTGGATGAAATTGA
CAAGATTGCCAAGAAGAGTGAGAATGTGTCTATCACACGTGATGTTTCTGGTGAAGGGGTGCAACAAGCCCTTCTCAAGA
TTATCGAGGGAACTGTTGCTAGCGTGCCGCCTCAAGGTGGACGCAAACATCCACAACAAGAGATGATTCAAGTGGATACA
AAAAATATCCTCTTCATCGTGGGTGGTGCTTTTGATGGTATTGAAGAAATTGTCAAACAACGTATGGGTGAAAAAGTCAT
CGGATTTGGTCAAAACAATAAGGCGATTGACGAAAACAGCTCATACATGCAAGAAATCATCGCTGAAGACATTCAAAAAT
TTGGTATTATCCCTGAGTTGATTGGACGCTTGCCTGTTTTTGCGGCTCTTGAGCAATTGACTGTTGATGACTTGGTTCGC
ATCTTGAAAGAGCCAAGAAATGCCTTGGTGAAACAATACCAAACCTTGCTTTCTTATGATGATGTTGAGTTGGAATTTGA
CGACGAAGCCCTTCAAGAGATTGCTAATAAAGCAATCGAACGGAAGACAGGGGCGCGTGGACTTCGCTCCATTATCGAAG
AAACCATGCTAGATGTTATGTTTGAGGTGCCGAGTCAGGAAAATGTGAAATTGGTTCGCATCACTAAAGAAACTGTCGAT
GGAACGGATAAACCGATCCTAGAAACAGCCTAG

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(111-306)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(313-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

86.341

100

0.863
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.965

98.049

0.559

Multiple sequence alignment