Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicX   Type   Regulator
Locus tag   E0F32_RS06025 Genome accession   NZ_LR216050
Coordinates   1131821..1132630 (-) Length   269 a.a.
NCBI ID   WP_001289493.1    Uniprot ID   Q9RCS5
Organism   Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1126821..1137630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F32_RS06010 (SAMEA3431333_01122) - 1129271..1131157 (-) 1887 WP_000150984.1 Eco57I restriction-modification methylase domain-containing protein -
  E0F32_RS06015 (SAMEA3431333_01123) - 1131232..1131486 (-) 255 WP_001809704.1 type II toxin-antitoxin system RelE family toxin -
  E0F32_RS06020 (SAMEA3431333_01124) relB 1131488..1131730 (-) 243 WP_024477795.1 type II toxin-antitoxin system RelB family antitoxin -
  E0F32_RS06025 (SAMEA3431333_01125) vicX 1131821..1132630 (-) 810 WP_001289493.1 MBL fold metallo-hydrolase Regulator
  E0F32_RS06030 (SAMEA3431333_01126) micB 1132632..1133981 (-) 1350 WP_000886210.1 cell wall metabolism sensor histidine kinase VicK Regulator
  E0F32_RS06035 (SAMEA3431333_01127) micA 1133974..1134678 (-) 705 WP_000722076.1 response regulator YycF Regulator
  E0F32_RS06040 (SAMEA3431333_01128) mutY 1134733..1135908 (-) 1176 WP_000886147.1 A/G-specific adenine glycosylase -
  E0F32_RS12160 - 1136005..1136130 (+) 126 WP_001818232.1 hypothetical protein -

Sequence

Protein


Download         Length: 269 a.a.        Molecular weight: 29916.89 Da        Isoelectric Point: 6.1743

>NTDB_id=1126112 E0F32_RS06025 WP_001289493.1 1131821..1132630(-) (vicX) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLLAEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMD
LYANEKTWQAMENSKYLGKVDSSQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKKIYLGHLSKENNIKELAHMTMVN
QLAQADLGVGVDFKVYDTSPDTATPLTEI

Nucleotide


Download         Length: 810 bp        

>NTDB_id=1126112 E0F32_RS06025 WP_001289493.1 1131821..1132630(-) (vicX) [Streptococcus pneumoniae strain GPSC10 substr. ST2013 isolate GPS_US_PATH396-sc-2296505]
ATGAGTGAAATAGGCTTTAAATACAGTATTTTAGCGTCGGGTTCCAGTGGAAATTCTTTTTATCTGGAAACCTCAAAAAA
GAAGCTTTTAGTAGATGCAGGCTTGTCTGGCAAGAAAATTACCAGTCTGCTAGCTGAAATTAACCGTAAGCCAGAAGACC
TGGATGCCATCTTGATTACCCATGAGCATTCAGATCATATCCATGGAGTAGGCGTTTTGGCTCGCAAGTATGGTATGGAT
CTTTATGCCAATGAAAAGACCTGGCAAGCTATGGAAAATAGTAAATATCTTGGCAAGGTGGATTCTTCGCAAAAGCATAT
TTTTGAAATGGGTAAAACCAAAACCTTTGGAGATATCGACATCGAGAGTTTTGGTGTAAGCCATGATGCAGTCGCACCGC
AGTTCTATCGCTTTATGAAGGATGATAAGAGTTTTGTCCTCTTGACAGATACAGGTTATGTCAGTGACCGTATGGCGGGC
ATTGTCGAAAATGCGGATGGTTATCTTATCGAGGCCAACCATGATGTAGAGATTTTGCGATCAGGTTCTTACGCTTGGCG
CCTCAAACAACGAATCCTATCTGACCTTGGTCACCTTTCTAACGAGGACGGTGCTGAAGCTATGATTCGGACGCTAGGAA
ATCGTACTAAGAAGATTTACCTTGGGCATTTATCTAAGGAAAACAATATCAAGGAACTGGCTCATATGACCATGGTCAAT
CAGCTGGCTCAAGCTGATCTGGGAGTCGGAGTAGACTTTAAGGTTTATGATACCTCACCAGATACCGCAACACCATTGAC
AGAGATATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(15-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9RCS5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicX Streptococcus mutans UA159

77.323

100

0.773

Multiple sequence alignment