Detailed information NTG0112500

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: LA58_RS04450
• Genome accession: NZ_CP009420
• Coordinates: 867880..870177 (-)
• Length: 765 a.a.
• NCBI ID: WP_002221163.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain NM3682
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 862880..875177

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LA58_RS04430	hldA	863408..864379 (+)	972	WP_002217546.1	ADP-heptose synthase	-
LA58_RS04435 (LA58_04685)	-	864416..865651 (+)	1236	WP_002221168.1	DNA cytosine methyltransferase	-
LA58_RS04440 (LA58_04690)	-	865653..866771 (+)	1119	WP_002221166.1	HNH endonuclease	-
LA58_RS04445 (LA58_04695)	rfaD	866812..867816 (+)	1005	WP_002221165.1	ADP-glyceromanno-heptose 6-epimerase	-
LA58_RS04450 (LA58_04700)	clpC	867880..870177 (-)	2298	WP_002221163.1	ATP-dependent Clp protease ATP-binding subunit ClpA	Regulator
LA58_RS04455 (LA58_04705)	clpS	870179..870481 (-)	303	WP_002221161.1	ATP-dependent Clp protease adapter ClpS	-
LA58_RS04460 (LA58_04710)	-	870724..870927 (+)	204	WP_002217533.1	cold-shock protein	-
LA58_RS04465 (LA58_04715)	pmbA	871224..872555 (-)	1332	WP_002221160.1	metalloprotease PmbA	-
LA58_RS04470 (LA58_04725)	yjgA	872710..873216 (+)	507	WP_002224594.1	ribosome biogenesis factor YjgA	-
LA58_RS04475 (LA58_04730)	-	873263..873997 (+)	735	WP_002221158.1	hypothetical protein	-

Sequence

Protein

• Length: 765 a.a.
• Molecular weight: 84475.28 Da
• Isoelectric Point: 6.6432

>NTDB_id=112500 LA58_RS04450 WP_002221163.1 867880..870177(-) (clpC) [Neisseria meningitidis strain NM3682]
MLAPELEQILQQLYREARKAHYEFISLEHLLLVLIEEDASVPNVLKLCGADLKVVSEQLAASVAENTPLIPEHLLDTVET
RPTLGFQRVMQRAMVHTQSAGKAAVEPLDVLVALMSETDSHTVYFLKLQSVTRFEVLRCIAHGSPDEDEDEDDGNYSSDG
MDDDNENRAKPGKNPLSAYTVNLNAEVKAGRIDPLIGRKHEMERLVQILCRRRKNNPLLVGEAGVGKTALAEGLAHQIVN
GGIPDALKDAEVYALDMGSLLAGTKYRGDFEARVKSVLKQLEKIPHAILFIDEIHTIIGAGSTSGGTMDASNLLKPALAK
GSLRCIGATTYDEYRTIFDKDHALSRRFQKIDVVEPTVSETVQILRGLKPMFEAFHQVRYTQGALEAAAELSARYINERF
LPDKAIDVMDEAGAAQRILPKSKQKKVIGKAQIETVIAKVSRIPEKTVSHDDKQVLQFLGRDLKNMVYGQENAIDALVAA
VKMSRSGLALPDKPIGSFLFSGPTGVGKTEAAKQLAYSLGVPLQRFDMSEYMERHAVSRLIGAPPGYVGFEQGGLLTEAV
NKQPHCVLLLDEIEKAHPDIFNVLLQVMDAGKLTDNNGKSADFRNVILIMTTNAGAESLSRPSLGFTAKRERGDEMQAIN
KLFTPEFRNRLDAIIPFAPLSEPIIVKVVDKFLLQLEHQLLDKKVEAEFTSALHKYLAEKGFDPQMGARPMHRLIQEKIR
KPLADELLFGKLSDGGFVRIDWDAAKEEAVLKFKKSKVKIKTASA

Nucleotide

• Length: 2298 bp

>NTDB_id=112500 LA58_RS04450 WP_002221163.1 867880..870177(-) (clpC) [Neisseria meningitidis strain NM3682]
ATGCTTGCACCCGAATTGGAACAGATTTTGCAGCAGCTTTACCGCGAGGCGCGTAAGGCTCATTATGAATTTATCAGCCT
CGAGCATCTGCTTTTGGTACTCATCGAAGAAGATGCCTCCGTGCCGAACGTCTTAAAACTATGCGGCGCGGATTTGAAAG
TGGTGTCCGAACAGCTCGCCGCCAGCGTTGCCGAAAACACCCCCCTGATTCCCGAACACCTTTTAGACACGGTCGAAACA
CGGCCCACGCTCGGCTTCCAACGCGTGATGCAACGGGCGATGGTGCATACCCAGTCTGCCGGAAAAGCCGCAGTCGAACC
GTTGGACGTTTTGGTCGCGCTGATGAGCGAAACCGACAGCCACACCGTCTATTTCCTCAAGCTGCAATCGGTTACGCGTT
TTGAAGTTTTGCGCTGTATTGCCCACGGCTCTCCCGATGAAGATGAAGATGAAGACGATGGCAACTATTCTTCAGACGGC
ATGGACGACGATAATGAAAACCGCGCCAAACCGGGCAAAAACCCTTTATCGGCGTACACCGTCAACCTCAACGCCGAAGT
CAAAGCCGGCCGTATCGACCCTTTGATTGGTCGCAAACACGAAATGGAACGGCTGGTGCAAATCCTATGCCGCCGCCGCA
AAAACAATCCGCTTTTGGTCGGCGAAGCGGGCGTGGGCAAAACCGCGCTGGCGGAAGGTTTGGCACATCAAATCGTCAAC
GGCGGCATTCCAGACGCGCTCAAAGATGCCGAAGTGTACGCGCTGGATATGGGCTCGCTGTTGGCGGGCACGAAATACCG
CGGCGACTTTGAAGCGCGGGTCAAATCCGTCTTGAAACAGCTCGAAAAAATCCCGCACGCCATTTTGTTTATCGACGAAA
TCCACACCATCATCGGCGCGGGCAGCACCAGCGGCGGCACCATGGACGCGTCCAACCTGCTCAAACCCGCGCTGGCAAAA
GGTTCGCTGCGCTGCATCGGCGCGACCACCTACGACGAATACCGCACCATTTTCGACAAAGACCATGCCTTAAGCCGCCG
CTTCCAAAAAATCGACGTGGTCGAACCCACCGTTTCCGAAACCGTTCAAATCCTGCGCGGCTTGAAACCGATGTTTGAAG
CCTTCCACCAAGTCCGCTACACTCAAGGCGCACTCGAAGCCGCCGCCGAACTCTCCGCACGCTACATCAACGAGCGTTTC
CTGCCCGACAAAGCCATCGACGTAATGGATGAAGCAGGCGCGGCGCAACGGATTCTGCCCAAATCCAAACAGAAAAAAGT
CATCGGCAAAGCACAAATCGAAACCGTCATCGCCAAAGTTTCGCGGATTCCCGAAAAAACCGTGTCGCACGACGACAAAC
AAGTGCTGCAATTCCTCGGTCGCGATTTGAAAAACATGGTTTACGGTCAAGAAAACGCCATCGACGCGCTGGTTGCCGCC
GTCAAAATGTCGCGTTCCGGCCTTGCCCTGCCCGACAAACCGATAGGCAGCTTCCTCTTCTCCGGCCCGACCGGCGTGGG
CAAAACCGAAGCCGCCAAACAGCTTGCCTACTCGCTGGGCGTACCGCTGCAACGCTTTGATATGTCCGAATACATGGAAC
GCCATGCCGTATCGCGCCTCATCGGCGCGCCACCGGGCTACGTCGGCTTTGAACAAGGCGGCCTTTTGACCGAAGCCGTC
AACAAACAGCCGCATTGCGTATTGCTCTTGGACGAAATCGAAAAAGCCCACCCCGACATTTTCAACGTCCTCCTGCAAGT
CATGGACGCAGGCAAACTGACCGACAACAACGGCAAGAGTGCCGATTTCCGCAACGTCATCCTGATTATGACCACCAACG
CAGGCGCGGAAAGCCTCAGCCGCCCCAGCCTCGGCTTTACCGCCAAGCGCGAACGCGGCGACGAAATGCAGGCAATCAAC
AAGCTCTTCACGCCCGAGTTCCGCAACCGCTTGGACGCGATTATCCCGTTTGCACCCTTGTCCGAACCCATCATCGTCAA
AGTCGTGGACAAATTCCTGCTCCAGCTCGAACACCAGCTCCTCGACAAAAAAGTCGAAGCCGAATTCACGTCGGCATTGC
ACAAATATCTGGCGGAAAAAGGTTTCGACCCGCAAATGGGCGCGCGCCCGATGCACCGCCTGATTCAGGAAAAAATCCGC
AAACCGCTCGCCGACGAACTCCTGTTCGGCAAACTATCCGACGGCGGCTTCGTGCGGATAGACTGGGATGCGGCAAAAGA
AGAAGCCGTGTTGAAGTTTAAGAAAAGCAAGGTCAAAATAAAAACCGCCTCCGCGTAA

Domains

Predicted by InterProScan.

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-61)

• ATPase family associated with various cellular activities (AAA) (AAA) (218-350)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (660-740)

• AAA domain (Cdc48 subfamily) (AAA_2) (493-654)

• AAA lid domain (AAA_lid_9) (358-455)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	38.386	100	0.41
clpC	Bacillus subtilis subsp. subtilis str. 168	37.129	100	0.392
clpA	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	41.609	94.248	0.392