Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   EL309_RS09315 Genome accession   NZ_LR134533
Coordinates   1937239..1939479 (+) Length   746 a.a.
NCBI ID   WP_004283556.1    Uniprot ID   A0A448VQI0
Organism   Neisseria weaveri strain NCTC12742     
Function   DNA processing; DNA transport into the cytoplasm (predicted from homology)   
DNA processing DNA binding and uptake

Genomic Context

Location: 1932239..1944479
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL309_RS09290 (NCTC12742_01839) ppx 1932738..1934246 (-) 1509 WP_004283568.1 exopolyphosphatase -
  EL309_RS09295 (NCTC12742_01840) - 1934486..1934902 (+) 417 WP_004283566.1 NfeD family protein -
  EL309_RS09300 (NCTC12742_01841) - 1934930..1935886 (+) 957 WP_107726493.1 SPFH domain-containing protein -
  EL309_RS09305 (NCTC12742_01842) rlmB 1936317..1937066 (-) 750 WP_004283560.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EL309_RS09315 (NCTC12742_01843) comA 1937239..1939479 (+) 2241 WP_004283556.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EL309_RS09320 (NCTC12742_01844) rep 1939544..1941553 (-) 2010 WP_004283555.1 DNA helicase Rep -
  EL309_RS09325 (NCTC12742_01845) - 1941769..1942128 (+) 360 WP_004283554.1 hypothetical protein -
  EL309_RS09330 (NCTC12742_01846) - 1942132..1942554 (+) 423 WP_004283553.1 protein YgfX -
  EL309_RS09335 (NCTC12742_01847) folC 1942862..1944154 (+) 1293 WP_004283552.1 bifunctional tetrahydrofolate synthase/dihydrofolate synthase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 81018.93 Da        Isoelectric Point: 9.4541

>NTDB_id=1124130 EL309_RS09315 WP_004283556.1 1937239..1939479(+) (comA) [Neisseria weaveri strain NCTC12742]
MALRFGLPFWIFGVLLSFALPVVPPLWVWTAVGCCAAVLFRRYRSLALLLLCLTVGAAYGVWRTEAALSQQWQTASAADL
TVTVDDLPQREARRVRFTAVAEDEAGRQYRLVLSDYGLRDWPVGSRWQVRARVRPPVGEVNPAGFNREAWALAKGIDGLG
TIGGERVLLAQGEAGRLLRMRDSVSRRWQQAAVVKPEFSDGQALMRALGIGEQTALDTGVWQAFRPLGLNHLVSISGLHV
GMVALFAGWLAKLLLACLPFSLSKPRLWMVSAGVAAGIFYAGLAGFSVPTQRSVLMLAALAWAWWCGSGVSVWRGWWQAL
AAVLLVQPAAVLGAGFWLSFGLVAALLWVASGRLNGLGWRAVLRGQWAVSVLSVVILGAFFASVPLISPLVNAAAIPWFS
WVLTPLALLGSILPWPRLHEFAAAAGEYTLRFLLWLAEYAPEYAVAEVPWPLVLLAVVAGGVLLLPKPTALRPWAALVLC
GFVVYRKEPVQYGRVQMVVWDAGQGLSVLFQTAQHRLLFDTGTAPSAAMNILPALNAWGVRSLDALVLSHHDADHDGGFE
AVARATRPKRLWAGQPQFYSGAESCDKGAWEWDGVHFEWLRPSEIVKADDNEQSCVLRVVAGGQAALVTGDLGKAGEKSL
VEQYGGGLHSNVLVLGHHGSDTSSSGVFLNAVAPEYAVASSGYANAYRHPVKAVRDRVQAHDIVLLRTDWQGALRFELGA
GGEVFGGPLRQRKPYWQKKPFDNAPY

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=1124130 EL309_RS09315 WP_004283556.1 1937239..1939479(+) (comA) [Neisseria weaveri strain NCTC12742]
ATGGCTTTGAGATTCGGTTTGCCGTTTTGGATTTTCGGCGTGTTACTGTCGTTTGCGTTGCCTGTCGTGCCGCCGTTGTG
GGTCTGGACGGCGGTCGGTTGCTGCGCGGCCGTATTGTTTCGGCGTTACCGCAGTTTGGCTTTATTGCTGTTGTGTTTGA
CGGTTGGGGCGGCTTACGGTGTGTGGCGGACGGAAGCGGCGTTGTCGCAGCAATGGCAGACGGCTTCTGCGGCGGATTTA
ACCGTTACGGTGGACGATTTGCCGCAACGTGAAGCACGGCGTGTGCGTTTTACGGCCGTGGCGGAGGACGAAGCGGGCAG
GCAGTACCGTTTGGTTTTGTCGGATTACGGTTTGCGCGATTGGCCGGTCGGCAGCCGCTGGCAGGTTCGCGCCCGCGTCC
GGCCGCCGGTCGGGGAAGTGAATCCGGCCGGTTTTAACCGTGAAGCGTGGGCTTTGGCGAAGGGTATAGACGGCTTGGGT
ACGATTGGCGGCGAACGTGTTTTGTTGGCGCAGGGCGAGGCCGGTCGGTTGCTGAGGATGCGCGATTCGGTCAGCAGGCG
TTGGCAGCAGGCGGCGGTGGTCAAGCCTGAATTTTCAGACGGCCAAGCGCTGATGCGGGCGTTGGGTATCGGCGAGCAGA
CGGCTTTGGATACGGGTGTGTGGCAGGCGTTCCGGCCTTTGGGTTTGAACCATTTGGTCAGTATTTCGGGATTGCATGTG
GGTATGGTGGCGTTGTTTGCCGGTTGGCTGGCAAAGTTGCTGCTGGCGTGTTTGCCGTTTTCGCTGTCGAAGCCGCGTTT
GTGGATGGTATCGGCAGGTGTGGCGGCCGGAATATTTTATGCCGGATTGGCTGGGTTTTCCGTGCCGACGCAGCGCAGTG
TATTGATGTTGGCGGCGTTGGCTTGGGCTTGGTGGTGCGGCAGCGGCGTATCGGTTTGGCGCGGTTGGTGGCAGGCGTTG
GCGGCCGTGCTGCTGGTTCAGCCTGCTGCGGTGTTGGGGGCGGGATTTTGGTTGTCGTTCGGTTTGGTGGCGGCACTGTT
GTGGGTTGCGTCAGGCCGTCTGAACGGTTTGGGTTGGCGTGCCGTATTAAGGGGACAATGGGCGGTATCGGTGTTGTCGG
TGGTGATATTGGGGGCATTTTTTGCTTCGGTGCCGCTGATCAGTCCTTTGGTGAATGCGGCGGCGATTCCGTGGTTTTCT
TGGGTGTTGACGCCGTTGGCCTTGCTCGGCTCTATATTGCCTTGGCCCCGGTTGCATGAATTTGCGGCGGCGGCAGGGGA
ATACACGCTGCGGTTTTTGTTGTGGCTGGCGGAGTATGCGCCCGAATATGCGGTGGCGGAGGTGCCGTGGCCGTTGGTAT
TGCTGGCGGTGGTAGCCGGAGGTGTGCTGTTGCTGCCGAAGCCGACGGCGTTGCGGCCTTGGGCGGCGTTGGTGTTGTGC
GGTTTTGTCGTGTATCGGAAAGAGCCTGTGCAATACGGGCGTGTGCAGATGGTGGTGTGGGACGCCGGGCAGGGTTTGTC
GGTGTTGTTTCAGACGGCGCAACATCGCTTGTTGTTTGATACGGGGACGGCGCCGTCGGCCGCCATGAATATTTTGCCTG
CGCTGAATGCTTGGGGCGTCCGCAGTTTGGATGCGCTGGTGTTGTCCCATCACGATGCCGACCATGACGGCGGTTTTGAA
GCGGTTGCCCGTGCCACGCGGCCGAAACGCTTGTGGGCGGGGCAGCCGCAGTTTTATTCGGGCGCGGAAAGTTGTGATAA
AGGAGCTTGGGAATGGGACGGGGTGCATTTCGAATGGTTGAGGCCGTCTGAAATTGTTAAGGCGGACGATAACGAGCAAA
GCTGTGTATTAAGGGTGGTTGCCGGCGGACAGGCGGCTTTGGTCACGGGGGATTTGGGCAAGGCAGGGGAGAAAAGTCTG
GTGGAACAATACGGCGGGGGTTTGCACAGCAATGTTTTGGTTTTGGGGCATCACGGCAGCGATACGTCGTCTTCCGGCGT
GTTTTTAAATGCGGTGGCGCCTGAATATGCGGTGGCTTCGAGCGGTTATGCCAATGCTTACCGCCATCCGGTCAAAGCCG
TGCGCGACCGTGTGCAGGCGCATGATATTGTGTTGCTGCGTACGGATTGGCAGGGCGCGTTGCGGTTTGAATTGGGCGCG
GGCGGCGAGGTGTTTGGCGGACCTTTGCGGCAGCGCAAACCTTATTGGCAGAAAAAGCCTTTTGATAATGCTCCGTATTG
A

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(501-649)

Domain of unknown function (DUF4131) (DUF4131)

(25-164)

Competence protein (Competence)

(209-464)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A448VQI0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Neisseria gonorrhoeae MS11

61.022

99.732

0.609

Multiple sequence alignment