Detailed information NTG1124045

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EL305_RS10915
• Genome accession: NZ_LR134528
• Coordinates: 1832463..1833323 (-)
• Length: 286 a.a.
• NCBI ID: WP_002226036.1
• Uniprot ID: A0A112F5U3
• Organism: Neisseria meningitidis strain NCTC12163
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1827463..1838323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL305_RS10875 (NCTC12163_01828)	ispB	1827949..1828923 (+)	975	WP_002216396.1	octaprenyl diphosphate synthase	-
EL305_RS10880 (NCTC12163_01829)	-	1828928..1829374 (+)	447	WP_002220271.1	DUF441 domain-containing protein	-
EL305_RS10900 (NCTC12163_01831)	pilF	1829866..1831542 (+)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EL305_RS10905 (NCTC12163_01832)	-	1831627..1831836 (-)	210	WP_002216401.1	DNA gyrase inhibitor YacG	-
EL305_RS10910 (NCTC12163_01833)	coaE	1831829..1832461 (-)	633	WP_002236672.1	dephospho-CoA kinase	-
EL305_RS10915 (NCTC12163_01834)	pilD	1832463..1833323 (-)	861	WP_002226036.1	prepilin peptidase	Machinery gene
EL305_RS10920 (NCTC12163_01835)	pilG	1833397..1834629 (-)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene
EL305_RS10930 (NCTC12163_01836)	pgi	1835138..1836781 (+)	1644	WP_002226984.1	glucose-6-phosphate isomerase	-
EL305_RS10935	-	1836751..1836981 (+)	231	WP_025458514.1	hypothetical protein	-
EL305_RS10940 (NCTC12163_01837)	dapD	1836991..1837812 (+)	822	WP_002216408.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31389.43 Da
• Isoelectric Point: 8.2213

>NTDB_id=1124045 EL305_RS10915 WP_002226036.1 1832463..1833323(-) (pilD) [Neisseria meningitidis strain NCTC12163]
MSDLSVLSPFAVPLTAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGEIGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=1124045 EL305_RS10915 WP_002226036.1 1832463..1833323(-) (pilD) [Neisseria meningitidis strain NCTC12163]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGACAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGTCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAATCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

3D structure

• AlphaFold DB: A0A112F5U3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	95.789	99.65	0.955
pilD	Vibrio cholerae strain A1552	44.097	100	0.444
pilD	Acinetobacter baumannii D1279779	46.97	92.308	0.434
pilD	Acinetobacter nosocomialis M2	46.97	92.308	0.434
pilD	Vibrio campbellii strain DS40M4	44.565	96.503	0.43