Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   EL305_RS10570 Genome accession   NZ_LR134528
Coordinates   1773723..1774421 (+) Length   232 a.a.
NCBI ID   WP_002215673.1    Uniprot ID   A0A0U1RKJ4
Organism   Neisseria meningitidis strain NCTC12163     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1768723..1779421
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL305_RS10550 (NCTC12163_01776) trpC 1769805..1770587 (-) 783 WP_002236649.1 indole-3-glycerol phosphate synthase TrpC -
  EL305_RS10555 (NCTC12163_01777) - 1770638..1771594 (-) 957 WP_126418101.1 YheT family hydrolase -
  EL305_RS14300 - 1771591..1771722 (-) 132 WP_255304562.1 hypothetical protein -
  EL305_RS10560 (NCTC12163_01778) murJ 1771726..1773264 (-) 1539 WP_002236651.1 murein biosynthesis integral membrane protein MurJ -
  EL305_RS14605 - 1773322..1773429 (+) 108 Protein_1784 IS5/IS1182 family transposase -
  EL305_RS10570 (NCTC12163_01779) dsbA1 1773723..1774421 (+) 699 WP_002215673.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  EL305_RS10575 (NCTC12163_01780) amgK 1774478..1775482 (-) 1005 WP_002215675.1 N-acetylmuramate/N-acetylglucosamine kinase AmgK -
  EL305_RS10580 (NCTC12163_01781) - 1775552..1777960 (+) 2409 WP_002245292.1 LPS-assembly protein LptD -
  EL305_RS10585 (NCTC12163_01782) - 1778065..1779090 (+) 1026 WP_002236653.1 peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 25245.84 Da        Isoelectric Point: 5.6016

>NTDB_id=1124041 EL305_RS10570 WP_002215673.1 1773723..1774421(+) (dsbA1) [Neisseria meningitidis strain NCTC12163]
MKSKHLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLTLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQEPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAH

Nucleotide


Download         Length: 699 bp        

>NTDB_id=1124041 EL305_RS10570 WP_002215673.1 1773723..1774421(+) (dsbA1) [Neisseria meningitidis strain NCTC12163]
ATGAAATCCAAACACCTCGCCCTCGGCGTTGCCGCCCTGTTCGCACTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACTGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTCTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTAAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAACACGTCGTCTGGCAGAA
AGAAATGCTGACGCTCGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAGATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAGAGCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCTTACGAATCTCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTCCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGCAAATATAAAGTCGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCACTAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(63-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0U1RKJ4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

98.707

100

0.987
  dsbA2 Neisseria meningitidis MC58

76.882

80.172

0.616

Multiple sequence alignment