Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA1   Type   Machinery gene
Locus tag   EL297_RS12735 Genome accession   NZ_LR134525
Coordinates   2151894..2152592 (+) Length   232 a.a.
NCBI ID   WP_002224844.1    Uniprot ID   Q9K189
Organism   Neisseria meningitidis strain NCTC10025     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2146894..2157592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL297_RS12715 (NCTC10025_02148) trpC 2148217..2148999 (-) 783 WP_082308675.1 indole-3-glycerol phosphate synthase TrpC -
  EL297_RS12720 (NCTC10025_02149) - 2149050..2150006 (-) 957 WP_082308676.1 YheT family hydrolase -
  EL297_RS13950 - 2150003..2150134 (-) 132 WP_255304562.1 hypothetical protein -
  EL297_RS12725 (NCTC10025_02150) murJ 2150138..2151676 (-) 1539 WP_105182954.1 murein biosynthesis integral membrane protein MurJ -
  EL297_RS12730 (NCTC10025_02151) - 2151676..2151867 (-) 192 WP_002260368.1 hypothetical protein -
  EL297_RS12735 (NCTC10025_02152) dsbA1 2151894..2152592 (+) 699 WP_002224844.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  EL297_RS12740 (NCTC10025_02153) amgK 2152649..2153653 (-) 1005 WP_002221582.1 N-acetylmuramate/N-acetylglucosamine kinase AmgK -
  EL297_RS12745 (NCTC10025_02154) - 2153723..2156131 (+) 2409 WP_167459873.1 LPS-assembly protein LptD -
  EL297_RS12750 (NCTC10025_02155) - 2156236..2157297 (+) 1062 WP_002249236.1 peptidylprolyl isomerase -

Sequence

Protein


Download         Length: 232 a.a.        Molecular weight: 25249.83 Da        Isoelectric Point: 5.6277

>NTDB_id=1123950 EL297_RS12735 WP_002224844.1 2151894..2152592(+) (dsbA1) [Neisseria meningitidis strain NCTC10025]
MKSRHLALGVAALFALAACDSKVQTSVPADSAPAASAAAAPAGLVEGQNYTVLANPIPQQQAGKVEVLEFFGYFCPHCAH
LEPVLSKHAKSFKDDMYLRTEHVVWQKEMLTLARLAAAVDMAAADSKDVANSHIFDAMVNQKIKLQNPEVLKKWLGEQTA
FDGKKVLAAYESPESQARADKMQELTETFQIDGTPTVIVGGKYKVEFADWESGMNTIDLLADKVREEQKAAQ

Nucleotide


Download         Length: 699 bp        

>NTDB_id=1123950 EL297_RS12735 WP_002224844.1 2151894..2152592(+) (dsbA1) [Neisseria meningitidis strain NCTC10025]
ATGAAATCCAGACACCTCGCCCTCGGCGTTGCCGCCCTGTTTGCCCTTGCCGCGTGCGACAGCAAAGTCCAAACCAGCGT
CCCCGCCGACAGCGCGCCTGCCGCTTCGGCAGCCGCCGCCCCGGCAGGGCTGGTCGAAGGGCAAAACTATACCGTCCTTG
CCAACCCGATTCCCCAACAGCAGGCAGGCAAAGTCGAAGTCCTTGAGTTTTTCGGCTATTTCTGTCCGCACTGCGCCCAC
CTCGAACCTGTTTTAAGCAAACACGCCAAGTCTTTTAAAGACGATATGTACCTGCGTACCGAACACGTCGTCTGGCAGAA
AGAAATGCTGACGCTGGCACGCCTCGCCGCCGCCGTCGATATGGCTGCCGCCGACAGCAAAGATGTGGCGAACAGCCATA
TTTTCGATGCGATGGTCAACCAAAAAATCAAGCTGCAAAATCCGGAAGTCCTCAAAAAATGGCTGGGCGAACAAACCGCC
TTTGACGGCAAAAAAGTCCTTGCCGCCTACGAGTCCCCCGAAAGCCAGGCGCGCGCCGACAAAATGCAGGAGCTGACCGA
AACCTTCCAAATCGACGGTACGCCCACGGTTATCGTCGGCGGTAAATATAAAGTTGAATTTGCCGACTGGGAGTCCGGTA
TGAACACCATCGACCTTTTGGCGGACAAAGTACGCGAAGAACAAAAAGCCGCGCAGTAA

Domains

Predicted by InterProScan.

Thioredoxin (Thioredoxin_4)

(63-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  PDB 3A3T
  PDB 3DVW
  PDB 3HZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA1 Neisseria meningitidis MC58

100

100

1
  dsbA2 Neisseria meningitidis MC58

76.19

81.466

0.621

Multiple sequence alignment