Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   EL256_RS00870 Genome accession   NZ_LR134517
Coordinates   179792..182155 (+) Length   787 a.a.
NCBI ID   WP_126442369.1    Uniprot ID   -
Organism   Helicobacter pylori strain NCTC13345     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 174792..187155
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL256_RS00835 (NCTC13345_00169) groES 174809..175165 (-) 357 WP_126442365.1 co-chaperone GroES -
  EL256_RS00845 (NCTC13345_00170) dnaG 175452..177131 (+) 1680 WP_126442366.1 DNA primase -
  EL256_RS00850 (NCTC13345_00171) - 177128..178180 (+) 1053 WP_126442367.1 MnmA/TRMU family protein -
  EL256_RS00855 (NCTC13345_00172) - 178273..179100 (+) 828 WP_126442368.1 DUF5718 family protein -
  EL256_RS00860 (NCTC13345_00173) comB2 179246..179527 (+) 282 WP_101000542.1 TrbC/VirB2 family protein Machinery gene
  EL256_RS00865 (NCTC13345_00174) comB3 179527..179790 (+) 264 WP_000584956.1 hypothetical protein Machinery gene
  EL256_RS00870 (NCTC13345_00175) comB4 179792..182155 (+) 2364 WP_126442369.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  EL256_RS00880 (NCTC13345_00177) - 182460..183800 (+) 1341 WP_164758890.1 COG3014 family protein -
  EL256_RS00885 (NCTC13345_00178) cheV1 183907..184872 (+) 966 WP_126442371.1 chemotaxis protein CheV1 -
  EL256_RS00890 (NCTC13345_00179) nspC 184869..186086 (+) 1218 WP_126442372.1 carboxynorspermidine decarboxylase -
  EL256_RS00895 (NCTC13345_00180) lpxE 186109..186654 (-) 546 WP_232007018.1 lipid A 1-phosphatase LpxE -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90179.58 Da        Isoelectric Point: 7.9822

>NTDB_id=1123748 EL256_RS00870 WP_126442369.1 179792..182155(+) (comB4) [Helicobacter pylori strain NCTC13345]
MLEKLLGAIKQKVSNYFLGALPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYKQNIQADSQYLQAILNQFENKEVYENQYFLVLESTHSLHGVLEHKKKSLMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSTHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNILIKAPSLEDLDTQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLVIGATGSGKSTLISFLMMSTLKYQNMRLLAFDRMQGL
YSFTEFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMLDLAPSRDKEALEDMNAISSAIKSLYETLYPKDFSLLDF
KETLKRTSSNQLGLSLEPYLNNPLFNALNDAFNSSAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=1123748 EL256_RS00870 WP_126442369.1 179792..182155(+) (comB4) [Helicobacter pylori strain NCTC13345]
ATGTTAGAAAAGCTTCTAGGCGCTATCAAACAAAAAGTTTCAAACTATTTTTTAGGGGCTTTGCCTAAAAGCTATTCTAT
GAGCGAAGAAAACAACATTTTAGGCTTGTATGATGAACATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATTCTCC
GTTTAGAGGGGGTGAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACCGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAAGTCGTGGCACGCCTAGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAACATTCAAGCTGACTCTCA
ATACTTGCAAGCAATTTTGAATCAATTTGAAAACAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTGCATGGCGTTTTGGAGCATAAGAAAAAATCCTTAATGCATGCCAATAGGGAAAATTTTAAGGATATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGTCTAGAAATCCAGCTCAAAAACTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAACGGGTTTGATCTCCCCTTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGCTATATCGCTAGTTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAATCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAAACGCC
TTTAGATATTATCTTTTCCATAGAGCCTATGAGCACGCATAAAACGCTGAGTTTTTTAAAAGAGAGAGCCAAGTTTAGCA
TGTCTAATCTTGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGATTATCCATGCAAAAATTCGCC
CTAAACATTCTTATCAAAGCCCCTAGTTTAGAGGATTTAGACACTCAAACCAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCACTTAAACC
ACCGCTTGCGTTTTTTGACCTCCAAAGCCCTAGCGTGTTTAATGGTGTTTGAAAGGCAAAATTTAGGTTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAACAACGCTAAAGAAATCGCTAGAGTGAATGGGCATACTTTAGTTATAGGGGCTACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCACTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAAGGGCTG
TATTCTTTTACCGAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATTTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTGGATCTCGCCCCTTCAAGGGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTAGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGATTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAATTGGGCTTGAGCTTAGAGCCGTATTTGAATAACCCCCTTTTTAACGC
TTTGAATGACGCGTTCAATTCCAGCGCTTTTTTAAACGTGATAAACCTAGATGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAGATCTTAGAAGAGTCCAGGAAAAACGACAGCGGCTTTTTGGTTTTTTTAGAC
GAATTTAAATCCTATGTGGAAAACGATTTGTTGAACACTAAAATCAACGCTTTAATCACGCAAGCCAGGAAAGCTAATGG
CGTGGTGGTGTTGGCTTTGCAAGACATTTACCAGTTAAGCGGGGTCAAAAACGCCCATAGTTTTTTAAGCAACATGGGGA
CTCTCATTTTGTATCCGCAAAAAAACGCTAGGGAATTGAAACACAATTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACGCCTTTGTATGCTAGGCAGGTTTTAGTCAAAAATCTGGGTAACGGGAGCTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCAGATTCCAGTCATGTGAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGCTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.332

100

0.973

Multiple sequence alignment