Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   EL247_RS03600 Genome accession   NZ_LR134509
Coordinates   710061..711905 (+) Length   614 a.a.
NCBI ID   WP_104745653.1    Uniprot ID   -
Organism   Helicobacter pullorum strain NCTC13154     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 705061..716905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL247_RS03575 (NCTC13154_00727) - 705813..706445 (-) 633 WP_104745657.1 SDR family oxidoreductase -
  EL247_RS03580 (NCTC13154_00728) rrpB 706672..707013 (+) 342 WP_104745656.1 MarR family transcription factor RrpB -
  EL247_RS03585 (NCTC13154_00729) - 707037..707885 (-) 849 WP_104745655.1 CoA ester lyase -
  EL247_RS03590 (NCTC13154_00730) - 708050..709516 (-) 1467 WP_054195739.1 L-aspartate oxidase -
  EL247_RS03595 (NCTC13154_00731) - 709618..710061 (+) 444 WP_104745654.1 hypothetical protein -
  EL247_RS03600 (NCTC13154_00732) uvrC 710061..711905 (+) 1845 WP_104745653.1 excinuclease ABC subunit UvrC Machinery gene
  EL247_RS03605 (NCTC13154_00733) - 711921..712262 (+) 342 WP_224757583.1 hypothetical protein -
  EL247_RS08525 - 712367..712522 (+) 156 WP_172594047.1 hypothetical protein -
  EL247_RS03610 (NCTC13154_00734) - 712557..713081 (+) 525 WP_104745708.1 ATP-grasp fold amidoligase family protein -
  EL247_RS03615 (NCTC13154_00735) ubiE 713100..713816 (-) 717 WP_104745651.1 bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE -
  EL247_RS03620 (NCTC13154_00736) argH 713806..715224 (-) 1419 WP_060663334.1 argininosuccinate lyase -
  EL247_RS03625 (NCTC13154_00737) hemJ 715241..715672 (-) 432 WP_005022820.1 protoporphyrinogen oxidase HemJ -
  EL247_RS03630 (NCTC13154_00738) - 715820..716494 (+) 675 WP_005022822.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70722.29 Da        Isoelectric Point: 9.6694

>NTDB_id=1123551 EL247_RS03600 WP_104745653.1 710061..711905(+) (uvrC) [Helicobacter pullorum strain NCTC13154]
MTEAKPLPLNEALAATLKKLPNKSGVYHYFDSEGRLLYIGKAKNLKNRIKSYFRFTPNLSVAPNLSARISQMVSQIASMR
YIVVENENDALILENSLIKQLKPKYNILLRDDKTYPYLCVDISEDYPRILLTRKVFKSQSIHYFGPYSSGGRDLLDSLYE
TFPLAQKESCLKGKKACLFYQIKRCLAPCEGKISKEDYRKILEQALECIQNPKKILAILDKKMQFLSENLRFEEAMVLRD
RIAKIKQISPLSGVDFARMEDLDIFALEIEGNKGVLVKFFVRGGRVVSSASNVIKSQYELNIEEIYTQSLINYYSGEILI
KPKQILIPYDLKEKKDELEQFLYQKLHKKIPIHCPKSGDKKQLCNLALKNAKESLNLNLTASEEILLDIQKLFGLQNMPY
RIEIFDTSHHRGKQCVGAMVVYDERFIKESYRHYLLEGSDEYSQMKEMLQRRIEKFKEEVPPDLWVLDGGVGQINLAKDL
LNSAGVNLEVVGISKEKLDSKAHRAKGAALDILRDEKGQEYRLKSSDKRLQFLQKLRDEAHRFAITFHQKQKQKTMQQSK
VLEVKGVGKAIQKRLLAYFGSFEGIKKASLDELEKILSKDLAKSVYDKMQHNLE

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=1123551 EL247_RS03600 WP_104745653.1 710061..711905(+) (uvrC) [Helicobacter pullorum strain NCTC13154]
ATGACAGAAGCCAAACCTTTGCCATTAAATGAAGCTTTGGCAGCAACGCTAAAAAAACTTCCTAATAAAAGTGGTGTGTA
TCATTATTTTGATAGCGAAGGAAGATTGCTTTATATCGGCAAAGCTAAGAATCTCAAAAATCGCATAAAAAGTTATTTTA
GATTTACTCCAAATCTTAGTGTGGCTCCAAATTTGAGTGCTAGAATCTCGCAAATGGTTTCGCAAATTGCTTCTATGCGT
TATATTGTGGTAGAAAACGAAAACGACGCACTAATTTTGGAAAATTCTTTGATTAAGCAATTAAAGCCAAAATACAATAT
TCTTTTGCGTGATGATAAGACTTATCCTTATTTGTGTGTGGATATTTCAGAGGATTACCCTCGTATTTTATTGACTAGGA
AGGTTTTTAAAAGTCAGAGTATTCATTATTTTGGACCTTATTCAAGTGGAGGAAGAGATTTGCTAGATTCTCTTTATGAA
ACTTTTCCTTTAGCACAAAAAGAAAGTTGTCTCAAAGGCAAAAAAGCTTGTCTTTTTTATCAAATTAAACGATGTTTAGC
TCCTTGTGAGGGCAAAATAAGCAAAGAGGATTATAGGAAAATTTTAGAACAAGCCCTAGAATGTATCCAAAATCCCAAAA
AAATTTTAGCCATTTTGGATAAAAAAATGCAATTTTTATCAGAAAATTTGCGGTTTGAGGAAGCAATGGTGCTACGCGAT
AGAATTGCAAAAATCAAGCAAATTAGTCCTTTATCGGGCGTGGATTTTGCAAGAATGGAGGACTTGGATATTTTTGCATT
GGAGATTGAGGGGAATAAAGGCGTTTTGGTTAAGTTTTTTGTGCGTGGGGGTAGGGTGGTTTCTAGTGCAAGCAATGTAA
TTAAGAGTCAATATGAATTAAACATTGAGGAAATTTATACGCAAAGTTTGATTAATTATTATAGTGGTGAAATTTTAATT
AAACCAAAACAGATTCTTATTCCTTATGACTTAAAAGAAAAAAAAGATGAGTTGGAGCAATTTTTGTATCAGAAATTGCA
CAAAAAGATTCCAATTCATTGTCCAAAAAGTGGAGACAAAAAACAGCTTTGTAACCTTGCTTTGAAAAATGCTAAAGAAA
GCTTAAATCTAAACCTTACTGCTAGTGAGGAAATACTGCTTGATATTCAAAAACTTTTTGGGCTACAAAATATGCCTTAT
AGAATCGAGATTTTTGATACTTCACACCATAGAGGCAAGCAGTGTGTGGGGGCTATGGTTGTTTATGATGAGAGGTTTAT
CAAAGAATCTTATCGGCATTATTTGCTAGAGGGGAGCGATGAATATTCGCAAATGAAGGAAATGCTGCAAAGACGCATTG
AGAAGTTCAAAGAAGAAGTTCCACCGGATTTGTGGGTGCTTGATGGGGGAGTTGGGCAAATTAATCTTGCAAAAGATTTG
CTAAATAGTGCGGGAGTGAATTTGGAGGTGGTGGGAATCTCTAAAGAGAAGCTAGATTCTAAAGCCCATAGGGCAAAAGG
GGCGGCATTAGATATTTTGCGTGATGAAAAAGGGCAGGAATATCGCTTAAAGAGCAGTGATAAGCGATTGCAGTTTTTGC
AGAAATTGAGAGATGAAGCGCATCGGTTTGCTATCACATTCCATCAAAAACAAAAGCAAAAAACAATGCAGCAAAGTAAA
GTTTTGGAAGTCAAGGGTGTAGGTAAGGCGATACAAAAAAGATTATTGGCTTATTTTGGAAGTTTTGAAGGGATTAAAAA
AGCAAGTTTAGATGAGCTAGAGAAGATCTTATCTAAAGACTTGGCAAAGAGTGTTTATGATAAAATGCAACACAATTTAG
AATGA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(24-106)

UvrB/uvrC motif (UVR)

(219-247)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(390-545)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

54.146

96.254

0.521

Multiple sequence alignment