Detailed information NTG1123035

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: EL215_RS03005
• Genome accession: NZ_LR134481
• Coordinates: 608673..609341 (+)
• Length: 222 a.a.
• NCBI ID: WP_126470118.1
• Uniprot ID: A0A3S4WRA7
• Organism: Haemophilus parainfluenzae strain NCTC10665
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	595563..618534	608673..609341	within	0

Gene organization within MGE regions

Location: 595563..618534

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL215_RS02940 (NCTC10665_00580)	gyrB	596380..598806 (+)	2427	WP_126470102.1	DNA topoisomerase (ATP-hydrolyzing) subunit B	-
EL215_RS02945 (NCTC10665_00581)	-	599058..600803 (+)	1746	WP_126470104.1	ABC transporter ATP-binding protein/permease	-
EL215_RS02950 (NCTC10665_00582)	cydC	600796..602454 (+)	1659	WP_126470106.1	thiol reductant ABC exporter subunit CydC	-
EL215_RS02955 (NCTC10665_00583)	coaA	602499..603434 (-)	936	WP_126470108.1	type I pantothenate kinase	-
EL215_RS02980 (NCTC10665_00588)	tuf	604136..605320 (+)	1185	WP_005635637.1	elongation factor Tu	-
EL215_RS02985 (NCTC10665_00589)	-	605477..606295 (+)	819	WP_126470110.1	Cof-type HAD-IIB family hydrolase	-
EL215_RS02990 (NCTC10665_00590)	crcB	606296..606691 (+)	396	WP_126470112.1	fluoride efflux transporter CrcB	-
EL215_RS02995 (NCTC10665_00591)	recX	606666..607118 (-)	453	WP_126470114.1	recombination regulator RecX	-
EL215_RS03000 (NCTC10665_00592)	recA	607188..608243 (-)	1056	WP_126470116.1	recombinase RecA	Machinery gene
EL215_RS03005 (NCTC10665_00593)	sxy/tfoX	608673..609341 (+)	669	WP_126470118.1	TfoX/Sxy family DNA transformation protein	Regulator
EL215_RS03030 (NCTC10665_00598)	def	614856..615365 (+)	510	WP_126470120.1	peptide deformylase	-
EL215_RS03035 (NCTC10665_00599)	fmt	615425..616381 (+)	957	WP_126470122.1	methionyl-tRNA formyltransferase	-
EL215_RS03040 (NCTC10665_00600)	rsmB	616381..617718 (+)	1338	WP_126470124.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
EL215_RS03045 (NCTC10665_00601)	-	617719..618534 (+)	816	WP_126470126.1	glycosyltransferase family A protein	-

Sequence

Protein

• Length: 222 a.a.
• Molecular weight: 25469.73 Da
• Isoelectric Point: 10.3445

>NTDB_id=1123035 EL215_RS03005 WP_126470118.1 608673..609341(+) (sxy/tfoX) [Haemophilus parainfluenzae strain NCTC10665]
MKILPIPNDNITKVCDLLNQLIGDVTSKNLFTGYGLFHKQKDMFAVWVNNKVYLRAKDELSIKLKGLGCKSFTTNELNKR
FVLSDYYALTESILKDNVLMRTLIILSITQIRKEKLDFALSNVGRIRDLPNLSIKYERALNKVGIDNVDTLRKIGAENAI
VRLKKADISASEAFYWRLRGALENRNCEFYTEKEKERGLSKLNEILSANGFRRCKRASKKVS

Nucleotide

• Length: 669 bp

>NTDB_id=1123035 EL215_RS03005 WP_126470118.1 608673..609341(+) (sxy/tfoX) [Haemophilus parainfluenzae strain NCTC10665]
ATGAAAATCCTACCGATACCTAATGATAATATTACCAAAGTATGTGATTTGCTAAATCAACTTATTGGAGATGTGACAAG
TAAGAATCTATTTACGGGATATGGCTTGTTTCATAAACAAAAAGATATGTTTGCTGTTTGGGTAAACAATAAAGTTTACT
TGCGAGCTAAGGATGAGCTTTCAATAAAATTAAAAGGACTTGGATGTAAATCTTTTACAACAAATGAACTCAATAAGCGT
TTTGTATTATCTGATTATTATGCTTTAACCGAAAGTATCTTAAAGGATAACGTTCTAATGAGAACGTTGATTATTCTTTC
AATTACTCAAATAAGGAAGGAGAAACTCGATTTTGCGCTATCTAATGTTGGGCGAATTAGGGACTTACCAAATTTATCGA
TAAAGTATGAACGAGCATTAAATAAAGTAGGGATTGACAATGTCGATACTTTACGAAAAATTGGTGCTGAAAATGCGATT
GTTCGTTTGAAGAAAGCGGATATTAGTGCAAGTGAAGCTTTTTATTGGCGACTTCGCGGAGCTTTGGAAAATCGTAATTG
TGAGTTTTACACTGAAAAAGAGAAGGAAAGAGGCCTTAGTAAACTTAATGAAATACTCTCCGCAAATGGATTTAGACGTT
GTAAACGAGCGTCTAAAAAGGTTAGTTAG

Domains

Predicted by InterproScan.

• TfoX N-terminal domain (TfoX_N) (17-110)

• TfoX C-terminal domain (TfoX_C) (125-197)

3D structure

• AlphaFold DB: A0A3S4WRA7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Haemophilus influenzae Rd KW20	57.416	94.144	0.541