Detailed information    

insolico Bioinformatically predicted

Overview

Name   CJE0566   Type   Regulator
Locus tag   EL187_RS04125 Genome accession   NZ_LR134471
Coordinates   778457..779113 (+) Length   218 a.a.
NCBI ID   WP_039650078.1    Uniprot ID   -
Organism   Campylobacter insulaenigrae strain NCTC12927     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 764021..815953 778457..779113 within 0


Gene organization within MGE regions


Location: 764021..815953
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL187_RS04030 (NCTC12927_00815) - 764021..766552 (-) 2532 WP_414973613.1 DNA translocase FtsK -
  EL187_RS04035 (NCTC12927_00816) flgL 766909..769149 (-) 2241 WP_039650056.1 flagellar hook-associated protein FlgL -
  EL187_RS04045 (NCTC12927_00818) - 769573..770517 (+) 945 WP_232012933.1 tyrosine-type recombinase/integrase -
  EL187_RS07760 (NCTC12927_00819) - 770556..770750 (+) 195 WP_232012934.1 hypothetical protein -
  EL187_RS04050 (NCTC12927_00820) - 770743..770928 (-) 186 WP_012661534.1 helix-turn-helix transcriptional regulator -
  EL187_RS04055 (NCTC12927_00821) - 771010..771285 (-) 276 WP_039650058.1 hypothetical protein -
  EL187_RS07710 (NCTC12927_00822) - 771279..772001 (-) 723 WP_039650062.1 Rha family transcriptional regulator -
  EL187_RS07765 (NCTC12927_00823) - 772128..772607 (-) 480 WP_232012935.1 helix-turn-helix domain-containing protein -
  EL187_RS04070 (NCTC12927_00824) - 772607..773458 (-) 852 WP_039650064.1 hypothetical protein -
  EL187_RS04080 (NCTC12927_00825) - 773579..774466 (-) 888 WP_039650066.1 hypothetical protein -
  EL187_RS04085 (NCTC12927_00826) - 774617..774823 (-) 207 WP_039650068.1 hypothetical protein -
  EL187_RS04090 (NCTC12927_00827) - 774807..775181 (-) 375 WP_039650071.1 hypothetical protein -
  EL187_RS04095 (NCTC12927_00828) - 775178..776044 (-) 867 WP_084593985.1 hypothetical protein -
  EL187_RS07680 (NCTC12927_00829) - 776066..776224 (-) 159 WP_158336217.1 hypothetical protein -
  EL187_RS04100 (NCTC12927_00830) - 776227..776406 (-) 180 WP_039650072.1 hypothetical protein -
  EL187_RS04105 (NCTC12927_00831) - 776754..777053 (-) 300 WP_052251965.1 hypothetical protein -
  EL187_RS04110 (NCTC12927_00832) - 777054..777260 (-) 207 WP_039650074.1 hypothetical protein -
  EL187_RS04120 (NCTC12927_00833) - 777535..778455 (+) 921 WP_039650076.1 helix-turn-helix domain-containing protein -
  EL187_RS04125 (NCTC12927_00834) CJE0566 778457..779113 (+) 657 WP_039650078.1 DNA/RNA endonuclease G Regulator
  EL187_RS04130 (NCTC12927_00835) - 779140..779970 (+) 831 WP_039650080.1 DNA-processing protein DprA -
  EL187_RS04135 (NCTC12927_00836) - 779967..780566 (+) 600 WP_039650083.1 phosphoribosyltransferase -
  EL187_RS07895 - 780591..780743 (-) 153 WP_232012936.1 hypothetical protein -
  EL187_RS04145 (NCTC12927_00837) - 780778..781116 (-) 339 WP_039650085.1 hypothetical protein -
  EL187_RS04150 (NCTC12927_00838) - 781354..781743 (-) 390 WP_039650087.1 peptidase, M15 family -
  EL187_RS04155 (NCTC12927_00839) - 781740..783017 (-) 1278 WP_039650089.1 hypothetical protein -
  EL187_RS04160 (NCTC12927_00840) - 783014..783376 (-) 363 WP_039650091.1 DUF1353 domain-containing protein -
  EL187_RS04165 (NCTC12927_00841) - 783378..783872 (-) 495 WP_039650093.1 hypothetical protein -
  EL187_RS04170 (NCTC12927_00842) - 783860..784483 (-) 624 WP_052251968.1 DUF4376 domain-containing protein -
  EL187_RS04175 (NCTC12927_00843) - 784494..784943 (-) 450 WP_039650095.1 hypothetical protein -
  EL187_RS04180 (NCTC12927_00844) - 784945..786396 (-) 1452 WP_170161463.1 hypothetical protein -
  EL187_RS04185 (NCTC12927_00845) - 786374..787012 (-) 639 WP_039650098.1 hypothetical protein -
  EL187_RS04190 (NCTC12927_00846) - 786993..787325 (-) 333 WP_039650100.1 hypothetical protein -
  EL187_RS04195 (NCTC12927_00847) - 787334..787771 (-) 438 WP_039650102.1 head-tail connector protein -
  EL187_RS04200 (NCTC12927_00848) - 787768..787959 (-) 192 WP_039650104.1 hypothetical protein -
  EL187_RS04205 (NCTC12927_00849) - 787979..789139 (-) 1161 WP_039650105.1 phage major capsid protein -
  EL187_RS04210 (NCTC12927_00850) - 789151..789702 (-) 552 WP_039650107.1 hypothetical protein -
  EL187_RS04215 (NCTC12927_00851) - 789771..790640 (-) 870 WP_039650109.1 hypothetical protein -
  EL187_RS04220 (NCTC12927_00852) - 790637..795865 (-) 5229 WP_039650111.1 hypothetical protein -
  EL187_RS04225 (NCTC12927_00853) - 795920..796243 (+) 324 WP_039650113.1 hypothetical protein -
  EL187_RS04230 (NCTC12927_00854) - 796235..796456 (-) 222 WP_039650115.1 hypothetical protein -
  EL187_RS04235 (NCTC12927_00855) - 796537..796908 (-) 372 WP_039650117.1 hypothetical protein -
  EL187_RS04240 (NCTC12927_00856) - 796905..797879 (-) 975 WP_039650119.1 hypothetical protein -
  EL187_RS04245 (NCTC12927_00857) - 797943..798293 (-) 351 WP_052251969.1 hypothetical protein -
  EL187_RS04250 (NCTC12927_00858) - 798294..798818 (-) 525 WP_084593986.1 hypothetical protein -
  EL187_RS04255 (NCTC12927_00859) - 798806..799975 (-) 1170 WP_039650120.1 phage portal protein -
  EL187_RS04260 (NCTC12927_00860) - 800094..801788 (+) 1695 WP_052251970.1 KAP family P-loop domain protein -
  EL187_RS04265 (NCTC12927_00861) - 801873..802502 (+) 630 WP_039650122.1 helix-turn-helix transcriptional regulator -
  EL187_RS04270 (NCTC12927_00862) - 802560..802880 (+) 321 WP_039650124.1 hypothetical protein -
  EL187_RS04275 (NCTC12927_00863) - 802897..803091 (+) 195 WP_039651386.1 hypothetical protein -
  EL187_RS04280 (NCTC12927_00864) - 803157..803441 (+) 285 WP_039650126.1 hypothetical protein -
  EL187_RS04285 (NCTC12927_00865) - 803480..804292 (-) 813 WP_039650128.1 DNA adenine methylase -
  EL187_RS04290 (NCTC12927_00866) - 804397..806028 (-) 1632 WP_039650130.1 terminase large subunit -
  EL187_RS04295 (NCTC12927_00867) - 806021..806656 (-) 636 WP_039650132.1 P27 family phage terminase small subunit -
  EL187_RS04300 (NCTC12927_00868) - 806874..807248 (-) 375 WP_039650134.1 HNH endonuclease -
  EL187_RS04305 (NCTC12927_00869) - 807252..807524 (-) 273 WP_039650136.1 hypothetical protein -
  EL187_RS04310 (NCTC12927_00870) - 807939..808271 (+) 333 WP_256374747.1 AAA family ATPase -
  EL187_RS04315 (NCTC12927_00871) - 808264..808797 (+) 534 WP_170161464.1 RloB domain-containing protein -
  EL187_RS04320 (NCTC12927_00872) - 808979..809164 (-) 186 WP_039650140.1 hypothetical protein -
  EL187_RS04325 (NCTC12927_00874) - 810008..810679 (+) 672 WP_052251971.1 HepT-like ribonuclease domain-containing protein -
  EL187_RS04330 (NCTC12927_00875) - 811114..812355 (-) 1242 WP_039650142.1 DUF2920 family protein -
  EL187_RS04335 (NCTC12927_00876) dnaE 812342..815953 (-) 3612 WP_039650144.1 DNA polymerase III subunit alpha -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25870.64 Da        Isoelectric Point: 9.9850

>NTDB_id=1122902 EL187_RS04125 WP_039650078.1 778457..779113(+) (CJE0566) [Campylobacter insulaenigrae strain NCTC12927]
MLKKIFLLALFTSLSFAKYTQYEPSEDFAKYFTKQNCSQVLDKFYYINCYDYNYKGTKAVAYKLEADNLKGEQIKKRPRF
EDDTNIPKKYRTTWNDYKNSGYDRGHTLSNASMRKTTQAQRSTFLMSNITPQNPQINQKVWNKIEKRERQAALKLGEIEV
LNLVNYDSNPQRIKNQIAIPISYIKIVKGNNFKECYKVPNYEMENLTIKRYKFNCDKI

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1122902 EL187_RS04125 WP_039650078.1 778457..779113(+) (CJE0566) [Campylobacter insulaenigrae strain NCTC12927]
ATGCTTAAAAAGATATTTTTATTAGCGTTATTTACCTCATTGTCTTTTGCAAAGTACACACAATATGAACCGAGTGAAGA
TTTTGCGAAGTATTTTACTAAACAAAACTGCTCTCAAGTTTTAGATAAATTTTATTATATTAATTGCTATGATTATAACT
ATAAAGGTACTAAAGCAGTAGCTTATAAATTAGAAGCAGATAATCTAAAAGGAGAACAAATCAAAAAACGCCCACGCTTT
GAAGATGATACAAATATACCTAAAAAATATCGCACTACTTGGAATGATTATAAAAATAGTGGTTATGATAGAGGACACAC
TCTTTCCAATGCTTCTATGAGAAAAACTACTCAAGCCCAAAGAAGTACATTCTTAATGAGTAATATTACTCCACAAAATC
CACAAATTAATCAAAAAGTATGGAATAAGATTGAAAAAAGAGAAAGACAAGCAGCTTTAAAGCTTGGAGAAATTGAAGTT
TTAAATTTAGTTAATTATGATAGCAACCCACAAAGAATAAAAAATCAAATTGCTATTCCAATCTCTTATATTAAGATTGT
AAAAGGTAATAATTTTAAAGAATGTTATAAAGTTCCAAATTATGAAATGGAAAATTTAACTATAAAAAGATATAAGTTTA
ATTGTGATAAAATATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(28-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  CJE0566 Campylobacter jejuni RM1221

83.41

99.541

0.83
  CJE1441 Campylobacter jejuni RM1221

83.256

98.624

0.821

Multiple sequence alignment