Detailed information NTG1122627

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: EL220_RS12225
• Genome accession: NZ_LR134388
• Coordinates: 2762548..2765283 (+)
• Length: 911 a.a.
• NCBI ID: WP_128130908.1
• Uniprot ID: -
• Organism: Legionella sainthelensi strain NCTC11988
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2757548..2770283

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL220_RS12205 (NCTC11988_02571)	gstA	2757954..2758556 (-)	603	WP_027270250.1	glutathione transferase GstA	-
EL220_RS12210 (NCTC11988_02572)	-	2758615..2759592 (-)	978	WP_027270251.1	hypothetical protein	-
EL220_RS12215 (NCTC11988_02573)	-	2759733..2761007 (-)	1275	WP_027270252.1	serine hydrolase domain-containing protein	-
EL220_RS12220 (NCTC11988_02574)	gltX	2761004..2762419 (-)	1416	WP_027270253.1	glutamate--tRNA ligase	-
EL220_RS12225 (NCTC11988_02575)	letS	2762548..2765283 (+)	2736	WP_128130908.1	two-component system sensor histidine kinase LetS	Regulator
EL220_RS12230 (NCTC11988_02576)	-	2765324..2766568 (+)	1245	WP_027270255.1	6-phosphofructokinase	-
EL220_RS12235 (NCTC11988_02577)	pilA2	2766858..2767289 (+)	432	WP_027270256.1	pilin	Machinery gene
EL220_RS12240 (NCTC11988_02578)	-	2767376..2767699 (+)	324	WP_027270257.1	BolA family protein	-
EL220_RS12245 (NCTC11988_02579)	-	2767864..2769264 (+)	1401	WP_027270258.1	APC family permease	-
EL220_RS12250 (NCTC11988_02580)	-	2769429..2769608 (-)	180	WP_027270259.1	Trm112 family protein	-
EL220_RS12255 (NCTC11988_02581)	tsaB	2769618..2770268 (-)	651	WP_027270260.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	-

Sequence

Protein

• Length: 911 a.a.
• Molecular weight: 102706.31 Da
• Isoelectric Point: 8.0072

>NTDB_id=1122627 EL220_RS12225 WP_128130908.1 2762548..2765283(+) (letS) [Legionella sainthelensi strain NCTC11988]
MLKSIGIKYQLRITTLIPVFLVALLLAIFYNGLFGNDLKQHMSRLGEAYIRQLLPAAQYAMLRGDDRTLQDLINASTINP
EVKALAFYSSDGQLLAYRGGKHSLSKPFTAPKFTGDYIKSKQINPFTINFIAPVTIPKFNLYSNSSFKNILSPMASRADD
ILGWLSIDIDTRSMIIKRYQMLIVTIFITLFGLLVGLTIHYFLSKQIYLPISRLRRSMKQILRNEFETEIKTTSSGELGI
IEQGCSHLQKKHLETIRDLNHHIEVATADLQQSLELLEEKNIELSLEKKKIEEKSRQKSEFIANMSHEIRTPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLGIINDILDFSKIDAGKLHLDCIPLNIRHCIDEVLALAAPNAHKKGIDLIPITE
LNVPKIVLGDPFRVKQFISNLVTNAVKFTDHGYVLIRTKVEQETDKDYTLCITITDTGLGISPEDQNKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMKGRITFASELNKGSVFTAYIKVEKLVAYEVEKNQVHPFAHFKMLCFDDNPMQLEALCNG
LGYWGVKCIAVPSLNQLANKLKNNKDCNIAFLNINKGYEQQITKLIAEHNYFPYVLTSKWLINDYTALGAQGFLYKPISI
QKLQDIIESLTNQENIEKSVNHELEGLREQLRFLHPDLLIAEDNPVNKMLLDSLLGTRANIVAVDNGEMAVSVCNEKKYS
LILLDLHMPKINGLEAARLIRQKSEFNRHTPIVLISANGRDVNDIDLKKSGVNFCLQKPIDEKQLLIQILRIADKAKHSA
IDWQLCVQKASGNQSLAEEFLARFVEELIKNREEFIQLMHEKNVKQLGEAAHKLHGACCFSGVPTLQKKVVQVEKLAAHA
ASIAELATPFAELIQSIDAVISEYENQKIKT

Nucleotide

• Length: 2736 bp

>NTDB_id=1122627 EL220_RS12225 WP_128130908.1 2762548..2765283(+) (letS) [Legionella sainthelensi strain NCTC11988]
ATCTTGAAAAGCATTGGTATTAAGTATCAACTAAGAATTACTACCTTAATCCCTGTTTTTCTGGTCGCCCTACTCCTTGC
CATTTTTTATAATGGGTTGTTTGGTAATGACTTAAAACAACACATGTCTCGCCTAGGCGAAGCATATATTCGACAATTAC
TCCCCGCCGCCCAGTATGCTATGCTGCGTGGAGACGATCGAACCTTACAGGACCTTATCAATGCATCAACAATTAATCCT
GAAGTCAAAGCACTCGCTTTTTACAGTAGCGATGGTCAACTCCTTGCTTATCGTGGAGGCAAACATTCACTAAGCAAACC
ATTTACTGCACCTAAATTCACTGGGGATTACATTAAAAGTAAACAAATTAACCCCTTTACTATCAACTTTATCGCCCCTG
TCACAATTCCAAAATTTAATTTGTATTCCAACTCTTCTTTTAAAAATATTTTAAGCCCGATGGCATCTCGAGCTGATGAT
ATTCTTGGTTGGTTGTCTATTGATATCGATACTCGCTCAATGATAATCAAACGTTATCAGATGCTTATTGTCACTATTTT
CATTACTTTATTCGGGTTATTAGTAGGATTAACCATTCACTACTTTCTCTCGAAACAAATTTATTTACCTATTTCTCGTT
TGCGAAGGAGCATGAAACAAATTTTACGTAACGAGTTTGAAACAGAGATAAAAACAACTAGCTCTGGAGAATTAGGAATA
ATTGAACAAGGTTGCTCGCATTTGCAAAAAAAACACCTTGAAACGATACGCGATCTAAACCACCACATTGAAGTAGCCAC
GGCTGATTTACAACAAAGTTTAGAGCTTTTAGAGGAAAAAAATATTGAACTTTCCCTTGAAAAGAAAAAAATTGAAGAAA
AAAGCCGGCAAAAGTCTGAATTTATCGCCAATATGAGTCATGAAATTCGTACTCCGATGAATGGAGTTATTGGTTTTACT
AATGTTTTACTTGAAAGTAAACTTGATCCTTTGCAATTAGATTATGTAAAAACAATTAAGTCATCAGCACAAGACTTATT
AGGGATTATCAATGACATTCTCGATTTCTCTAAAATTGATGCGGGAAAACTGCATCTCGATTGTATTCCATTAAATATTC
GCCACTGTATTGATGAAGTACTCGCTCTTGCAGCGCCTAATGCCCATAAAAAAGGGATCGACTTAATTCCTATCACCGAA
CTGAACGTACCTAAGATTGTTTTAGGAGACCCCTTTAGAGTAAAACAGTTTATTAGCAACCTGGTAACTAATGCAGTTAA
ATTTACTGATCATGGATATGTATTAATCCGTACTAAAGTAGAGCAGGAAACGGATAAAGATTACACTTTATGCATTACAA
TTACGGATACAGGCTTAGGTATTTCTCCTGAAGATCAAAACAAACTGTTTACCGCCTTTAATCAGGCAGATACCAGTATT
ACTCGTCGTTATGGCGGATCAGGACTTGGTTTGGTAATCTGTAAAAAACTCTGTGAAGAAATGAAAGGCCGCATTACTTT
TGCCAGTGAGCTCAACAAAGGTTCTGTTTTTACTGCTTATATCAAGGTTGAAAAATTAGTTGCCTATGAAGTTGAAAAAA
ACCAAGTTCATCCTTTTGCTCATTTTAAAATGCTTTGTTTTGACGATAACCCCATGCAGCTGGAGGCCTTGTGTAATGGA
TTAGGCTATTGGGGAGTCAAATGTATCGCTGTACCTTCACTAAATCAACTCGCGAATAAGCTGAAAAATAATAAAGATTG
CAACATCGCTTTTCTTAATATCAATAAAGGTTATGAACAACAAATTACTAAGCTAATAGCCGAGCATAATTATTTTCCTT
ATGTGTTGACCTCTAAATGGCTTATTAATGATTATACAGCACTTGGTGCCCAAGGATTTTTATATAAACCCATCAGTATC
CAAAAACTCCAAGATATTATTGAGTCATTAACAAACCAAGAAAATATTGAAAAGTCAGTTAATCATGAATTAGAAGGTTT
AAGGGAACAATTACGTTTCCTACATCCAGATCTTCTTATAGCTGAAGATAATCCAGTGAATAAAATGCTTCTTGACTCTT
TATTAGGTACTCGTGCCAATATTGTAGCGGTTGATAATGGAGAAATGGCTGTATCGGTGTGTAATGAAAAGAAATACAGT
CTTATCTTACTTGACCTACATATGCCTAAAATCAATGGCTTAGAAGCCGCTCGACTTATTCGTCAAAAATCAGAATTCAA
TCGTCATACACCCATAGTATTAATTAGTGCAAATGGTAGAGATGTAAATGATATTGATTTAAAAAAATCAGGGGTAAATT
TTTGTTTGCAAAAACCCATAGATGAAAAACAATTATTGATCCAAATTTTACGTATTGCAGATAAAGCAAAGCACTCTGCA
ATAGATTGGCAATTGTGTGTTCAAAAAGCCTCTGGAAATCAATCGCTAGCCGAAGAGTTCCTTGCTCGATTTGTAGAAGA
ATTGATTAAAAACCGTGAAGAATTCATCCAATTAATGCATGAAAAAAATGTGAAACAATTGGGCGAAGCAGCACATAAAC
TTCATGGAGCATGTTGTTTTAGTGGTGTCCCCACATTACAAAAAAAGGTGGTTCAAGTAGAAAAACTTGCTGCTCATGCT
GCTTCAATCGCAGAATTAGCTACTCCTTTTGCAGAATTAATTCAAAGCATCGACGCAGTAATTAGTGAATACGAAAATCA
AAAAATAAAAACGTAG

Domains

Predicted by InterproScan.

• Single cache domain 4 (sCache_4) (36-180)

• Response regulator receiver domain (Response_reg) (679-787)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Hpt domain (Hpt) (819-900)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	78.39	99.561	0.78