Detailed information NTG1122507

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: EL201_RS09810
• Genome accession: NZ_LR134380
• Coordinates: 2155866..2158598 (+)
• Length: 910 a.a.
• NCBI ID: WP_027222091.1
• Uniprot ID: -
• Organism: Legionella pneumophila subsp. pascullei strain NCTC12273
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2150866..2163598

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL201_RS09790 (NCTC12273_01966)	gstA	2151011..2151616 (-)	606	WP_027222087.1	glutathione transferase GstA	-
EL201_RS09795 (NCTC12273_01967)	-	2151811..2152806 (-)	996	WP_027222088.1	hypothetical protein	-
EL201_RS09800 (NCTC12273_01968)	-	2152847..2154109 (-)	1263	WP_027222089.1	serine hydrolase domain-containing protein	-
EL201_RS09805 (NCTC12273_01969)	gltX	2154355..2155767 (-)	1413	WP_027222090.1	glutamate--tRNA ligase	-
EL201_RS09810 (NCTC12273_01970)	letS	2155866..2158598 (+)	2733	WP_027222091.1	two-component system sensor histidine kinase LetS	Regulator
EL201_RS09815 (NCTC12273_01971)	-	2158696..2159940 (+)	1245	WP_027222092.1	6-phosphofructokinase	-
EL201_RS09820 (NCTC12273_01972)	pilA2	2159937..2160350 (-)	414	WP_027222093.1	pilin	Machinery gene
EL201_RS09825 (NCTC12273_01973)	pilA2	2160546..2160956 (-)	411	WP_011214168.1	pilin	Machinery gene
EL201_RS09830 (NCTC12273_01974)	-	2161258..2161575 (+)	318	WP_027222094.1	BolA family protein	-
EL201_RS09835 (NCTC12273_01975)	-	2161650..2163071 (+)	1422	WP_027222095.1	APC family permease	-

Sequence

Protein

• Length: 910 a.a.
• Molecular weight: 103088.56 Da
• Isoelectric Point: 7.6532

>NTDB_id=1122507 EL201_RS09810 WP_027222091.1 2155866..2158598(+) (letS) [Legionella pneumophila subsp. pascullei strain NCTC12273]
MLKSIGIKYQLRITTLIPAFLVALLFAFFYNGLFGKDLKQHMSRLGEAYIRQLLPAAQYAMLRNDYRTLQGLINASTINP
EVKALAFYNADGRLIAYRGGKHSIHKPFNPPDYTGDYIESKQINPFTINFIAPITIPKFNLYSSTEFKEPSTPKVFQADD
ILGWLSIDIDTQSLLIKRYQMLIVTIFITLFGLLMGLTIHYFLSKRIYMPIARLRRSMKQILSNEFETEIRVSSPGELGI
IEKGCAHLQRQYLNTVRDLNHHIEIATADLQQSLELLEEKNIELSLEKKKTEEKSRQKSEFIANMSHEIRKPMNGVIGFT
NVLLESKLDPLQLDYVKTIKSSAQDLLSIINDILDFSKIDAGKLNLDCIPLDIRGCIDEVLSLASPNAHKKGIDLIPITD
INVPKMVLGDPLRIKQIISNLVTNAVKFTDHGYVLIRTKIEQETDKDYTLLFAITDTGIGISPEDQTKLFTAFNQADTSI
TRRYGGSGLGLVICKKLCEEMHGRISLTSEINKGSTFSARIKVEKLVAYEIEKNQTHRFAHLKIICFDDNPLHLEAMGNG
LGFWGIEAIRVDSFNKLSRTLTKHKDCKIAFINVNQGCERQAAELIAKHKQIPFVLISKWPINDFAALGARGFLYKPISI
QKLQDLIESIANENQTEKNTNQELDTLREQLRFLHPELLIAEDNPVNKMLLTSLLNNNANITTVDDGEMAFTACEDKKFD
MILLDLQMPKLNGLEAAKMIRQKSLMNKHSPIVLITASSSDLSSIDMKKSGVDYCFQKPIDEKQLLIQILRIVDKTKHAA
IDWQLCVQKVSGNQALAEEFLAKFIEELYKNREEFIELMHQKNVKGLADLAHKLHGACCFCGVPILQKRVAQLEKLARRT
ANADNLTEAFTDLIQSIDAVISEYENQYSQ

Nucleotide

• Length: 2733 bp

>NTDB_id=1122507 EL201_RS09810 WP_027222091.1 2155866..2158598(+) (letS) [Legionella pneumophila subsp. pascullei strain NCTC12273]
ATGTTGAAAAGTATTGGTATTAAGTATCAGCTAAGAATCACTACTCTTATTCCTGCCTTTTTAGTTGCCTTGCTTTTTGC
CTTTTTTTATAACGGTCTATTTGGTAAAGATCTAAAGCAGCATATGTCCAGACTGGGTGAAGCCTACATTAGACAATTAC
TCCCAGCCGCCCAGTATGCCATGCTTCGCAATGATTATCGTACATTACAGGGTTTAATCAATGCCTCAACCATTAATCCA
GAGGTAAAGGCTTTGGCATTTTATAATGCCGATGGTCGATTAATTGCTTATCGTGGTGGCAAGCACTCTATTCATAAACC
CTTCAATCCGCCTGACTATACCGGTGACTACATTGAAAGTAAGCAAATTAATCCATTCACCATTAATTTTATAGCGCCGA
TTACTATCCCAAAGTTCAATTTGTACTCCAGTACAGAATTCAAAGAGCCTTCTACGCCTAAAGTATTTCAAGCCGACGAT
ATATTAGGCTGGCTATCTATTGACATTGATACACAATCACTCCTTATAAAACGCTATCAAATGCTTATTGTTACCATTTT
TATTACTCTCTTCGGTTTACTCATGGGTTTAACAATTCATTACTTCTTGTCTAAACGAATTTACATGCCTATTGCTCGAT
TGCGTAGAAGTATGAAACAAATTTTAAGTAATGAATTTGAAACAGAAATTCGTGTTTCAAGTCCAGGAGAATTAGGAATA
ATTGAAAAAGGTTGCGCTCATTTGCAACGACAATATTTAAATACGGTTCGCGATCTGAATCACCATATTGAAATCGCTAC
CGCAGATCTGCAACAAAGTCTCGAACTTCTGGAAGAAAAAAACATTGAGCTATCACTGGAGAAGAAAAAAACTGAAGAAA
AAAGCCGGCAAAAATCAGAATTTATTGCCAACATGAGTCATGAAATACGTAAACCAATGAATGGAGTGATTGGTTTTACC
AATGTTTTATTGGAAAGCAAGCTGGATCCTTTACAACTGGACTACGTTAAAACAATCAAATCATCAGCGCAGGATTTGTT
AAGTATCATCAATGATATTCTGGATTTTTCTAAAATTGATGCGGGCAAATTAAATCTCGATTGCATCCCGCTAGACATAA
GAGGCTGCATTGATGAGGTTTTATCCCTGGCAAGCCCCAATGCGCACAAAAAAGGAATAGATTTAATCCCGATTACAGAC
ATTAATGTGCCCAAAATGGTATTGGGTGACCCTTTAAGAATCAAGCAAATCATCAGTAATCTGGTGACCAATGCAGTAAA
ATTTACAGACCATGGATACGTTCTTATACGCACTAAAATAGAGCAAGAAACAGATAAAGATTATACCTTGCTATTTGCCA
TTACGGATACGGGAATAGGTATTTCACCAGAGGATCAAACGAAACTGTTTACTGCCTTCAATCAGGCAGATACCAGCATC
ACACGCCGTTACGGTGGATCAGGATTGGGCTTGGTGATATGTAAAAAATTATGTGAAGAAATGCATGGGCGCATTAGTCT
AACCAGTGAAATAAACAAAGGCTCTACTTTTAGCGCACGCATTAAAGTTGAAAAACTTGTTGCTTATGAGATTGAAAAAA
ATCAAACTCATCGTTTCGCCCATTTAAAAATCATTTGCTTTGATGACAATCCTCTCCATTTGGAAGCAATGGGTAATGGC
TTGGGCTTTTGGGGTATAGAAGCTATACGCGTTGATTCATTTAATAAACTTTCCCGAACATTGACAAAACATAAAGATTG
CAAAATTGCCTTTATTAATGTCAATCAAGGATGTGAGCGTCAAGCCGCTGAACTCATTGCCAAACATAAGCAAATTCCTT
TCGTATTAATTTCCAAATGGCCTATCAATGATTTTGCGGCGCTAGGTGCTCGAGGATTTCTTTACAAACCTATCAGCATC
CAAAAGCTTCAGGATTTGATTGAATCGATAGCTAATGAAAACCAAACTGAGAAAAATACTAACCAGGAACTGGATACTTT
ACGCGAACAACTTCGCTTTCTTCATCCAGAGCTACTGATTGCAGAAGACAACCCAGTCAATAAAATGCTATTAACATCCC
TATTAAACAATAATGCCAATATAACAACGGTTGATGATGGCGAAATGGCCTTTACTGCTTGTGAGGATAAAAAATTTGAC
ATGATTTTACTGGATCTGCAAATGCCAAAACTTAATGGTTTGGAAGCAGCCAAAATGATACGCCAAAAATCCCTAATGAA
TAAACACTCTCCTATCGTTCTCATTACCGCCAGTAGCAGTGATCTGAGCTCCATCGATATGAAAAAATCTGGAGTTGATT
ATTGTTTTCAAAAACCTATAGATGAAAAACAATTGTTAATCCAAATTCTTCGCATCGTTGATAAAACCAAACATGCTGCC
ATCGATTGGCAATTATGTGTTCAGAAAGTTTCAGGTAATCAAGCGCTTGCTGAAGAGTTCCTCGCCAAATTTATAGAAGA
ATTATATAAGAATCGTGAAGAATTTATTGAGTTAATGCATCAAAAAAACGTAAAGGGTCTGGCTGATTTGGCTCATAAAT
TACATGGCGCCTGTTGTTTTTGTGGTGTGCCTATTTTACAAAAGAGAGTAGCTCAATTAGAGAAACTTGCAAGACGAACA
GCTAATGCTGATAATTTAACCGAAGCCTTTACTGATTTAATACAAAGTATTGATGCAGTGATTAGTGAATATGAAAATCA
GTATTCGCAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (298-362)

• Response regulator receiver domain (Response_reg) (679-787)

• Single cache domain 4 (sCache_4) (36-180)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (409-524)

• Hpt domain (Hpt) (819-899)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	98.791	100	0.988