Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   EL201_RS06225 Genome accession   NZ_LR134380
Coordinates   1355458..1356786 (+) Length   442 a.a.
NCBI ID   WP_027221416.1    Uniprot ID   A0AAX2IUW0
Organism   Legionella pneumophila subsp. pascullei strain NCTC12273     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1350458..1361786
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL201_RS06205 (NCTC12273_01247) amrS 1350587..1351663 (+) 1077 WP_027221412.1 AmmeMemoRadiSam system radical SAM enzyme -
  EL201_RS06210 (NCTC12273_01248) - 1351722..1352141 (+) 420 WP_027221413.1 lpg1171 family Dot/Icm T4SS effector -
  EL201_RS06215 (NCTC12273_01249) lidL 1352291..1353775 (+) 1485 WP_080273046.1 Dot/Icm type IV secretion system effector LidL -
  EL201_RS06220 (NCTC12273_01250) - 1353875..1355461 (+) 1587 WP_027221415.1 sensor histidine kinase -
  EL201_RS06225 (NCTC12273_01251) pilR 1355458..1356786 (+) 1329 WP_027221416.1 sigma-54-dependent transcriptional regulator Regulator
  EL201_RS06230 (NCTC12273_01252) - 1357050..1357295 (+) 246 WP_011213531.1 hypothetical protein -
  EL201_RS06235 (NCTC12273_01254) - 1357427..1358863 (-) 1437 WP_027221417.1 M48 family metalloprotease -
  EL201_RS06240 (NCTC12273_01255) ribD 1358926..1359999 (+) 1074 WP_027221418.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  EL201_RS06245 (NCTC12273_01256) - 1359984..1360598 (+) 615 WP_027221419.1 riboflavin synthase -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 49165.14 Da        Isoelectric Point: 6.5929

>NTDB_id=1122496 EL201_RS06225 WP_027221416.1 1355458..1356786(+) (pilR) [Legionella pneumophila subsp. pascullei strain NCTC12273]
MTKSKVLVIDDEPDIRELLTLTLSRMGLACDAVSDFKQGLEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQLPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPVDLKMLRDLVKTALSMQNPSTENPDEGLLVGESLVMQQLRESIHKLARSQAPVFI
QGDSGVGKELVAQLIHANGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEIPVDVRILSASHKSLIEEINAGKFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
KKLSKNQNRSLVKINPACFEILSHYHFPGNVRELENILERAMAMCEEEIIEPGDLHLPRTTITPVVAASPVSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=1122496 EL201_RS06225 WP_027221416.1 1355458..1356786(+) (pilR) [Legionella pneumophila subsp. pascullei strain NCTC12273]
ATGACTAAAAGCAAAGTGCTCGTTATAGATGACGAACCAGACATAAGAGAGTTATTAACTCTTACTTTATCGCGCATGGG
CTTAGCTTGCGATGCGGTGTCTGATTTTAAGCAGGGCTTAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ACATGCGTTTGCCTGATGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCACAGTTGCCAGTTGCTGTC
ATTACCGCTTATGGAAATGTCGAGGGTGCGGTCAATACTTTAAAGGCTGGGGCATTTGATTATGTATCCAAACCCGTAGA
CTTAAAGATGCTTAGAGATCTAGTCAAGACCGCATTATCCATGCAAAATCCGTCTACCGAAAATCCTGATGAAGGTTTAT
TGGTTGGTGAGAGTTTGGTAATGCAACAACTTCGTGAAAGCATCCATAAATTAGCTCGCAGTCAGGCACCGGTTTTTATT
CAAGGTGATTCAGGTGTTGGGAAAGAACTTGTTGCTCAGCTGATTCATGCTAATGGTCCCAGAAAAGATAAGCCATTTAT
TCCTGTAAATTGTGGTGCTATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTATTTGTTGCGGCTCATGGTGGCACTTTGTTTCTTGATGAAATCGCCGAGCTTCCTCTC
GCCATGCAGGTTAAATTACTACGTGCAATTCAAGAGAAGGCAATTAAACCAATAGGTGAGTTATATGAAATTCCGGTGGA
TGTACGCATTCTAAGTGCGAGCCATAAAAGTTTGATTGAGGAAATCAATGCAGGGAAGTTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGTGTCCCAACTTTAATGGAAAGACTTTCTGATATTCCTTGCCTGACGGAGGCGATATTA
AAAAAATTATCTAAAAATCAAAATAGAAGCCTGGTCAAAATCAATCCAGCCTGTTTTGAAATATTGAGTCATTATCATTT
TCCAGGGAATGTCAGAGAATTGGAGAATATCCTCGAGCGTGCCATGGCTATGTGTGAGGAAGAGATCATAGAACCAGGCG
ATTTACATTTGCCTAGAACGACAATAACCCCAGTTGTTGCTGCATCCCCAGTGTCAACTAACTTAAATGGTTATCTTCAG
GATCAGGAAAAGGAATTAATTCTAGATGCTCTTGAGAAAACAAAATGGAACAGGACAGCCGCTGCACAACTATTAGGTGT
CAGCTTCCGCACTCTCCGTTATCGATTAAAAAAACTGGGCCTTGATTAG

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(134-300)

Response regulator receiver domain (Response_reg)

(6-115)

Bacterial regulatory protein, Fis family (HTH_8)

(399-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.326

100

0.597
  pilR Acinetobacter baumannii strain A118

48.802

100

0.507

Multiple sequence alignment