Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   EL239_RS04435 Genome accession   NZ_LR134374
Coordinates   1026374..1027705 (-) Length   443 a.a.
NCBI ID   WP_126338475.1    Uniprot ID   -
Organism   Legionella spiritensis strain NCTC12082     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1021374..1032705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL239_RS04415 (NCTC12082_00899) ribA 1021590..1022798 (-) 1209 WP_126338467.1 GTP cyclohydrolase II -
  EL239_RS04420 (NCTC12082_00900) - 1022795..1023409 (-) 615 WP_126338469.1 riboflavin synthase -
  EL239_RS04425 (NCTC12082_00901) ribD 1023394..1024467 (-) 1074 WP_126338471.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  EL239_RS04430 (NCTC12082_00902) - 1024677..1026062 (+) 1386 WP_232001761.1 M48 family metalloprotease -
  EL239_RS04435 (NCTC12082_00904) pilR 1026374..1027705 (-) 1332 WP_126338475.1 sigma-54-dependent transcriptional regulator Regulator
  EL239_RS04440 (NCTC12082_00905) - 1027702..1029291 (-) 1590 WP_126338477.1 sensor histidine kinase -
  EL239_RS04445 (NCTC12082_00906) - 1029573..1030391 (+) 819 WP_126338479.1 hypothetical protein -
  EL239_RS04450 (NCTC12082_00907) - 1030453..1031094 (-) 642 WP_126338481.1 SDR family NAD(P)-dependent oxidoreductase -
  EL239_RS04455 (NCTC12082_00908) - 1031240..1031623 (-) 384 WP_126338483.1 hypothetical protein -

Sequence

Protein


Download         Length: 443 a.a.        Molecular weight: 48783.16 Da        Isoelectric Point: 6.5037

>NTDB_id=1122390 EL239_RS04435 WP_126338475.1 1026374..1027705(-) (pilR) [Legionella spiritensis strain NCTC12082]
MSKSKILIIDDEPDICELLSITLNRMGLSCETANSCQQGMNYINRHDYSLVLTDMRLPDGDGIELVKHIQKNKPQIPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLPMLKELVKTALSMQQNPMAAGDDRLLGDSPVMRELRQNIGKLARSQAPVFIL
GESGVGKELVAQLIHSEGPRSDKPFIPVNCGAIPSELMESEFFGHKKGSFTGAISDKAGLFVAAQGGTLFLDEVAELPVT
MQVKLLRAIQEKAIKPIGEHNEVPVDVRILSASHKNLQDEIASGRFRQDLYYRVNVIELQVPALRERISDIPGLANHILQ
NLASQQNRNIEPLSRACIQRLQSYHFPGNVRELENILERALAMCDGEAIAVDDIHLPVTPSKAATESSCESAAKNLDGSL
VEHEKELILNALEKTKWNRTAAARLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1332 bp        

>NTDB_id=1122390 EL239_RS04435 WP_126338475.1 1026374..1027705(-) (pilR) [Legionella spiritensis strain NCTC12082]
ATGAGTAAGTCCAAGATTCTGATCATTGATGACGAACCTGATATTTGCGAATTATTGTCAATCACCTTGAACCGCATGGG
ATTAAGCTGTGAAACGGCGAACAGTTGCCAGCAGGGAATGAACTATATTAACAGGCACGACTACTCACTGGTGTTAACGG
ACATGCGTCTGCCGGATGGGGACGGTATTGAACTGGTTAAACACATTCAGAAAAACAAACCCCAGATCCCTGTGGCAGTC
ATTACGGCCTATGGAAATGTGGAAGGAGCCGTCAATACCTTGAAAGCGGGGGCTTTTGATTATGTATCCAAGCCCATTGA
TTTACCTATGCTTAAGGAACTCGTGAAAACCGCGTTATCCATGCAACAAAACCCCATGGCGGCCGGCGATGACAGATTGC
TCGGCGATAGTCCGGTTATGAGGGAGCTTCGGCAGAATATCGGCAAACTGGCCCGCAGCCAGGCGCCGGTGTTTATTCTT
GGCGAGTCGGGGGTGGGTAAGGAGCTGGTGGCTCAATTGATTCACAGCGAAGGGCCGCGCAGCGACAAACCTTTTATTCC
GGTTAATTGCGGCGCCATTCCTTCGGAATTAATGGAGTCGGAGTTTTTTGGGCATAAAAAAGGAAGCTTTACCGGCGCTA
TTTCCGATAAAGCCGGTTTGTTTGTCGCAGCGCAGGGGGGGACGTTATTTCTGGACGAAGTCGCTGAATTACCGGTAACC
ATGCAGGTTAAATTGCTTCGCGCCATTCAGGAAAAAGCGATAAAACCCATCGGCGAACATAATGAAGTCCCGGTGGATGT
CAGGATTCTTAGCGCCAGCCATAAAAATTTACAGGATGAAATCGCATCAGGACGATTTCGACAGGATTTGTATTACCGGG
TTAACGTTATTGAACTGCAGGTACCCGCGTTGCGGGAGCGCATCTCGGATATTCCGGGGTTAGCTAACCATATTCTGCAA
AATCTGGCAAGTCAGCAGAATCGTAATATTGAGCCGTTGTCCAGGGCATGTATTCAGCGTTTGCAATCGTATCATTTTCC
AGGAAATGTCCGGGAGCTTGAAAATATTCTTGAGCGCGCTCTGGCTATGTGCGACGGTGAAGCGATTGCCGTAGATGACA
TCCACCTTCCGGTTACGCCAAGCAAGGCGGCAACGGAATCATCATGTGAATCTGCCGCGAAAAACCTTGATGGCTCTCTT
GTTGAGCATGAAAAGGAACTGATACTGAACGCACTGGAAAAAACGAAGTGGAATAGAACGGCGGCAGCCAGATTGTTAGG
GGTCAGTTTCAGAACGTTACGGTATCGACTGAAGAAACTGGGGCTGGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(6-115)

Sigma-54 interaction domain (Sigma54_activat)

(134-300)

Bacterial regulatory protein, Fis family (HTH_8)

(402-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.865

100

0.603
  pilR Acinetobacter baumannii strain A118

48.156

100

0.501

Multiple sequence alignment