Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EL140_RS01570 Genome accession   NZ_LR134336
Coordinates   308329..309018 (+) Length   229 a.a.
NCBI ID   WP_000518040.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 303329..314018
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS01545 (NCTC11427_00302) gpsB 303387..303716 (+) 330 WP_000146523.1 cell division regulator GpsB -
  EL140_RS01555 (NCTC11427_00304) - 304202..305359 (+) 1158 WP_000662905.1 THUMP domain-containing class I SAM-dependent RNA methyltransferase -
  EL140_RS01560 (NCTC11427_00305) mapZ 305372..306817 (+) 1446 WP_000039241.1 cell division site-positioning protein MapZ -
  EL140_RS01565 (NCTC11427_00306) gndA 306893..308317 (+) 1425 WP_000158766.1 NADP-dependent phosphogluconate dehydrogenase -
  EL140_RS01570 (NCTC11427_00307) covR 308329..309018 (+) 690 WP_000518040.1 response regulator transcription factor Regulator
  EL140_RS01575 (NCTC11427_00308) - 309118..310002 (+) 885 WP_000670351.1 N-acetylmuramoyl-L-alanine amidase family protein -
  EL140_RS01580 (NCTC11427_00309) cbpC 310020..311039 (+) 1020 WP_000771067.1 choline-binding protein CbpC -
  EL140_RS01585 (NCTC11427_00310) mvk 311157..312035 (+) 879 WP_000163304.1 mevalonate kinase -
  EL140_RS01590 (NCTC11427_00311) mvaD 312017..312970 (+) 954 WP_000375370.1 diphosphomevalonate decarboxylase -
  EL140_RS01595 (NCTC11427_00312) - 312957..313964 (+) 1008 WP_000562407.1 phosphomevalonate kinase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26843.00 Da        Isoelectric Point: 8.0271

>NTDB_id=1121834 EL140_RS01570 WP_000518040.1 308329..309018(+) (covR) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MGKRILLLEKERNLSHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRTKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1121834 EL140_RS01570 WP_000518040.1 308329..309018(+) (covR) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCTCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTCGAGGAGGGGCAAAAAGCCCTTTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGACAAAACCTGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACATTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATTTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAACTTGACGTAAAAGGTCAAA
AGAGCTACATTAAAACCGTGCGTGGTGTTGGTTACACCATGCAGGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.696

100

0.489
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.491

99.563

0.463

Multiple sequence alignment