Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   EL140_RS01295 Genome accession   NZ_LR134336
Coordinates   233994..234818 (+) Length   274 a.a.
NCBI ID   WP_000359002.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 228994..239818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS01260 (NCTC11427_00243) asnA 229084..230076 (+) 993 WP_000747998.1 aspartate--ammonia ligase -
  EL140_RS01265 (NCTC11427_00244) rsmD 230141..230680 (+) 540 WP_002874201.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  EL140_RS01270 (NCTC11427_00245) coaD 230670..231158 (+) 489 WP_001280719.1 pantetheine-phosphate adenylyltransferase -
  EL140_RS01275 (NCTC11427_00246) sepM 231142..232179 (+) 1038 WP_000730772.1 SepM family pheromone-processing serine protease Regulator
  EL140_RS01280 - 232235..232465 (+) 231 WP_002874202.1 DUF1146 family protein -
  EL140_RS01285 (NCTC11427_00247) murA 232489..233772 (+) 1284 WP_000411908.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  EL140_RS01290 (NCTC11427_00248) - 233759..233953 (+) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  EL140_RS01295 (NCTC11427_00249) endA 233994..234818 (+) 825 WP_000359002.1 DNA/RNA non-specific endonuclease Machinery gene
  EL140_RS01300 (NCTC11427_00250) - 234954..236285 (+) 1332 WP_000390016.1 hemolysin family protein -
  EL140_RS01310 (NCTC11427_00252) amiA 236788..238767 (+) 1980 WP_000749706.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 30070.70 Da        Isoelectric Point: 9.8219

>NTDB_id=1121824 EL140_RS01295 WP_000359002.1 233994..234818(+) (endA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQSAPNNPRTKVNQKKQASEAPSQELAESVLTESIKNQIKGNLEWNGAGAFVV
NGNKTNLDAKVSSKPYADNKTKTVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGTYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKVLDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=1121824 EL140_RS01295 WP_000359002.1 233994..234818(+) (endA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGATTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTACTACATCAAGCA
GATGCAGTCAGCACCAAATAACCCTAGAACCAAGGTTAATCAGAAAAAACAAGCTTCAGAAGCACCCAGTCAGGAGTTGG
CAGAAAGTGTCTTAACCGAGTCAATCAAAAACCAAATCAAGGGTAATCTCGAGTGGAATGGAGCAGGGGCCTTTGTTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCAAGCAAACCCTATGCGGATAATAAAACAAAGACAGTGGGAAAAGA
AACAGTTCCAACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAGAATCGTGAAGAGACTGGAAATGGCT
CAACCTCTTGGACGCCACCAGGATGGCATCAGGTTAAGAATCTAAAGGGAACCTACACACATGCAGTTGATAGAGGACAC
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACTAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCCAACCAGGCTCAGGCTGAAGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGTCTTGGACC
AAAATAAGAGAGTCCGTTATCGGGTGACGCTCCACTATGCGACAAATGAGGACTTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCGAAC
AGGGCAAGTAACAGTGACAGATTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

88.645

99.635

0.883
  endA Streptococcus pneumoniae D39

88.645

99.635

0.883
  endA Streptococcus pneumoniae R6

88.645

99.635

0.883
  endA Streptococcus pneumoniae TIGR4

88.645

99.635

0.883

Multiple sequence alignment