Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   EL176_RS13810 Genome accession   NZ_LR134332
Coordinates   3039747..3040406 (-) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila strain NCTC11193     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3034747..3045406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL176_RS13795 (NCTC11193_02742) - 3035547..3036206 (+) 660 WP_010948343.1 hypothetical protein -
  EL176_RS13800 (NCTC11193_02743) lcl 3036374..3037855 (+) 1482 WP_010948344.1 collagen-like adhesin Lcl -
  EL176_RS13805 (NCTC11193_02744) uvrC 3037879..3039735 (-) 1857 WP_010948345.1 excinuclease ABC subunit UvrC -
  EL176_RS13810 (NCTC11193_02745) letA 3039747..3040406 (-) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  EL176_RS13815 (NCTC11193_02746) phhA 3040531..3041349 (-) 819 WP_010948347.1 phenylalanine 4-monooxygenase -
  EL176_RS13820 (NCTC11193_02747) - 3041788..3042885 (+) 1098 WP_010948348.1 competence/damage-inducible protein A -
  EL176_RS13825 (NCTC11193_02748) cgtA 3042844..3043869 (-) 1026 WP_010948349.1 Obg family GTPase CgtA -
  EL176_RS13830 (NCTC11193_02749) rpmA 3044084..3044362 (-) 279 WP_010948350.1 50S ribosomal protein L27 -
  EL176_RS13835 (NCTC11193_02750) rplU 3044375..3044686 (-) 312 WP_010948351.1 50S ribosomal protein L21 -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=1121732 EL176_RS13810 WP_011216518.1 3039747..3040406(-) (letA) [Legionella pneumophila strain NCTC11193]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1121732 EL176_RS13810 WP_011216518.1 3039747..3040406(-) (letA) [Legionella pneumophila strain NCTC11193]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTAGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTAGCCTATGTAAAAACCCACTCCCCTGATGTCGTATTATTAG
ATATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACGCGTCGTTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCT
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCAGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCTAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTTCAGGAGTCTCAGGATTCCCCTTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment