Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EL133_RS04750 Genome accession   NZ_LR134323
Coordinates   919230..920456 (+) Length   408 a.a.
NCBI ID   WP_006740460.1    Uniprot ID   G5KFH4
Organism   Streptococcus urinalis strain NCTC13766     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 914230..925456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL133_RS04720 (NCTC13766_00980) - 914422..914859 (-) 438 WP_006738401.1 DUF1836 domain-containing protein -
  EL133_RS04725 (NCTC13766_00981) - 914960..916237 (-) 1278 WP_006738777.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EL133_RS04730 (NCTC13766_00982) - 916221..917402 (-) 1182 WP_006739294.1 hydroxymethylglutaryl-CoA synthase -
  EL133_RS04735 (NCTC13766_00983) - 917591..918430 (+) 840 WP_006740238.1 thymidylate synthase -
  EL133_RS04740 (NCTC13766_00984) - 918514..919023 (+) 510 WP_006738710.1 dihydrofolate reductase -
  EL133_RS04745 (NCTC13766_00985) - 919025..919195 (+) 171 WP_006739029.1 hypothetical protein -
  EL133_RS04750 (NCTC13766_00986) clpX 919230..920456 (+) 1227 WP_006740460.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EL133_RS04755 (NCTC13766_00987) yihA 920468..921067 (+) 600 WP_006740136.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EL133_RS04760 (NCTC13766_00988) - 921098..923197 (-) 2100 WP_006738451.1 AAA family ATPase -
  EL133_RS04765 (NCTC13766_00990) rplJ 923586..924086 (+) 501 WP_006739227.1 50S ribosomal protein L10 -
  EL133_RS04770 (NCTC13766_00991) rplL 924151..924519 (+) 369 WP_006739684.1 50S ribosomal protein L7/L12 -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45075.32 Da        Isoelectric Point: 4.4119

>NTDB_id=1121532 EL133_RS04750 WP_006740460.1 919230..920456(+) (clpX) [Streptococcus urinalis strain NCTC13766]
MANNRTNDTKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELSEEVLADLAEVPKPKELLDILNQYVVGQDK
AKKALSVAVYNHYKRISYTENQDEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTEASVPPQGGRKHPNQEMIQINTKS
ILFIVGGAFDGIEEIVKQRLGEKVIGFGQSNRKIDDDASYMQEITSEDIQKFGLIPEFIGRLPVLAALENLTTDDLVRIL
TEPRNALVKQYQALLSYDGVDLEFDKEALETIANKAIDRKTGARGLRSIIEETMLDIMFEIPSQEEITKVTITKEAVEGT
EKPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1121532 EL133_RS04750 WP_006740460.1 919230..920456(+) (clpX) [Streptococcus urinalis strain NCTC13766]
ATGGCTAATAATCGAACAAACGATACCAAAGTGTATTGCTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATCAT
AGCTGGCAACAATGTTTTCATTTGTAATGAATGTGTTGCTTTATCACAAGAAATTATCAAAGAAGAACTTTCTGAAGAGG
TTCTTGCTGATTTGGCTGAAGTACCAAAACCTAAAGAACTTCTTGATATCCTAAATCAATATGTAGTAGGACAAGATAAA
GCTAAAAAAGCTTTATCAGTCGCTGTATACAATCATTATAAACGGATTTCATATACGGAAAATCAAGATGAAGATGTTGA
TTTACAAAAATCAAATATTCTTATGATTGGGCCAACTGGTTCTGGTAAAACATTCTTAGCACAAACTTTAGCGAAAAGTT
TGAATGTTCCATTCGCAATTGCAGATGCTACATCACTCACAGAAGCAGGATATGTTGGTGAAGATGTTGAGAATATTTTA
TTGAAATTAATACAAGCTGCTGATTATAATGTTGAACGTGCTGAACGTGGTATTATCTATGTCGATGAGATTGATAAAAT
TGCTAAAAAAGGTGAAAATGTTTCTATCACACGTGACGTATCAGGAGAAGGTGTACAACAAGCATTACTTAAAATAATTG
AGGGAACTGAAGCGAGCGTCCCTCCTCAAGGTGGCCGCAAACATCCCAATCAAGAAATGATTCAAATAAATACTAAAAGT
ATTTTATTTATTGTTGGTGGTGCTTTTGACGGTATCGAAGAAATTGTAAAACAGCGTTTAGGTGAAAAAGTAATTGGTTT
TGGTCAATCTAATCGTAAGATTGATGATGATGCTTCTTATATGCAAGAAATCACCTCTGAAGATATCCAAAAATTTGGAC
TTATCCCTGAATTTATCGGACGTTTACCAGTTTTAGCTGCCTTAGAAAACTTAACGACTGATGATTTGGTTAGGATTTTA
ACAGAACCACGAAATGCACTTGTTAAACAATATCAAGCCTTATTATCTTATGACGGAGTTGATTTAGAATTTGATAAAGA
AGCATTGGAAACTATTGCAAATAAAGCAATTGACCGTAAAACAGGTGCGCGTGGATTACGTTCAATCATTGAAGAAACAA
TGTTAGATATCATGTTTGAAATTCCAAGTCAAGAAGAGATTACTAAAGTGACAATAACAAAAGAAGCAGTTGAAGGAACA
GAAAAACCTGTTCTTGAAACTGCCTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5KFH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

87.286

100

0.875
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.25

98.039

0.561

Multiple sequence alignment