Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EL130_RS06345 Genome accession   NZ_LR134320
Coordinates   1259389..1260621 (+) Length   410 a.a.
NCBI ID   WP_002262816.1    Uniprot ID   A0AAX1K4W9
Organism   Streptococcus mutans strain NCTC10832     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1254389..1265621
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS06320 (NCTC10832_01218) - 1255461..1256636 (-) 1176 WP_002266471.1 hydroxymethylglutaryl-CoA synthase -
  EL130_RS06325 (NCTC10832_01219) - 1256844..1257683 (+) 840 WP_019320513.1 thymidylate synthase -
  EL130_RS06330 (NCTC10832_01220) pnuC 1257800..1258579 (+) 780 WP_002266473.1 nicotinamide riboside transporter PnuC -
  EL130_RS06335 (NCTC10832_01221) - 1258664..1259176 (+) 513 WP_002262814.1 dihydrofolate reductase -
  EL130_RS06340 (NCTC10832_01222) - 1259194..1259364 (+) 171 WP_002262815.1 hypothetical protein -
  EL130_RS06345 (NCTC10832_01223) clpX 1259389..1260621 (+) 1233 WP_002262816.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EL130_RS06350 (NCTC10832_01224) yihA 1260637..1261230 (+) 594 WP_002262817.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EL130_RS06355 (NCTC10832_01225) - 1261560..1262936 (+) 1377 WP_002272474.1 amino acid permease -
  EL130_RS06360 (NCTC10832_01226) mmuM 1262946..1263896 (+) 951 WP_002283145.1 homocysteine S-methyltransferase -
  EL130_RS06365 (NCTC10832_01227) - 1264030..1265292 (-) 1263 WP_002283146.1 PLP-dependent aminotransferase family protein -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 45181.65 Da        Isoelectric Point: 4.4495

>NTDB_id=1121434 EL130_RS06345 WP_002262816.1 1259389..1260621(+) (clpX) [Streptococcus mutans strain NCTC10832]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1121434 EL130_RS06345 WP_002262816.1 1259389..1260621(+) (clpX) [Streptococcus mutans strain NCTC10832]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTGTTGGCAATACTAGACAGTTATGTTATCGGTCAGGACCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATT
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATTCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACGCTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACCGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-388)

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

100

100

1
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

59.102

97.805

0.578

Multiple sequence alignment