Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EL130_RS04270 Genome accession   NZ_LR134320
Coordinates   829975..831276 (+) Length   433 a.a.
NCBI ID   WP_002283397.1    Uniprot ID   A0A829BSR9
Organism   Streptococcus mutans strain NCTC10832     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 824975..836276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS04250 (NCTC10832_00808) - 826125..826793 (+) 669 WP_002283395.1 fructose-6-phosphate aldolase -
  EL130_RS04255 (NCTC10832_00809) - 826831..827922 (+) 1092 WP_002267044.1 glycerol dehydrogenase -
  EL130_RS04260 (NCTC10832_00810) cysK 828256..829182 (-) 927 WP_002263028.1 cysteine synthase A -
  EL130_RS04265 (NCTC10832_00811) - 829273..829902 (-) 630 WP_002283396.1 YigZ family protein -
  EL130_RS04270 (NCTC10832_00812) comFA/cflA 829975..831276 (+) 1302 WP_002283397.1 DEAD/DEAH box helicase Machinery gene
  EL130_RS04275 (NCTC10832_00813) - 831273..831938 (+) 666 WP_002270131.1 ComF family protein -
  EL130_RS04280 (NCTC10832_00814) hpf 832017..832565 (+) 549 WP_002263024.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL130_RS04285 (NCTC10832_00815) - 832689..833783 (+) 1095 WP_002264404.1 hypothetical protein -
  EL130_RS04290 (NCTC10832_00816) - 833803..835503 (+) 1701 WP_002296115.1 zinc ribbon domain-containing protein -
  EL130_RS04295 (NCTC10832_00817) - 835583..836218 (-) 636 WP_002272863.1 hypothetical protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49540.66 Da        Isoelectric Point: 9.9111

>NTDB_id=1121423 EL130_RS04270 WP_002283397.1 829975..831276(+) (comFA/cflA) [Streptococcus mutans strain NCTC10832]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASPRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRDKLPHSFLQQIRIQRQTQFPLLIFFPNIEDGLTFTKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1121423 EL130_RS04270 WP_002283397.1 829975..831276(+) (comFA/cflA) [Streptococcus mutans strain NCTC10832]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAAACTC
TGGCCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTCCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCTTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGATAAATTACCGCACTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGACTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTACTAAATCA
CTGCAAACTTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAAATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAGAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)

Type III restriction enzyme, res subunit (ResIII)

(94-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A829BSR9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae D39

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae R6

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae TIGR4

59.251

98.614

0.584
  comFA/cflA Streptococcus mitis NCTC 12261

58.782

98.614

0.58
  comFA/cflA Streptococcus mitis SK321

58.314

98.614

0.575
  comFA Lactococcus lactis subsp. cremoris KW2

51.523

90.993

0.469
  comFA Latilactobacillus sakei subsp. sakei 23K

38.498

98.383

0.379

Multiple sequence alignment