Detailed information    

insolico Bioinformatically predicted

Overview

Name   hdrM   Type   Regulator
Locus tag   EL130_RS00355 Genome accession   NZ_LR134320
Coordinates   69591..70277 (+) Length   228 a.a.
NCBI ID   WP_002278087.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCTC10832     
Function   repress competence development; negative regulate HdrR activity (predicted from homology)   
Competence regulation

Genomic Context

Location: 64591..75277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL130_RS00335 - 66718..66939 (+) 222 WP_019312622.1 hypothetical protein -
  EL130_RS00340 (NCTC10832_00064) - 67339..68283 (+) 945 WP_002262667.1 magnesium transporter CorA family protein -
  EL130_RS00345 (NCTC10832_00065) - 68437..69099 (+) 663 WP_002278088.1 DUF1129 domain-containing protein -
  EL130_RS00350 (NCTC10832_00066) hdrR 69238..69594 (+) 357 WP_002262669.1 LytTR family transcriptional regulator HdrR Regulator
  EL130_RS00355 (NCTC10832_00067) hdrM 69591..70277 (+) 687 WP_002278087.1 hdrR negative regulator HdrM Regulator
  EL130_RS00360 (NCTC10832_00068) - 70285..71004 (-) 720 WP_002270704.1 TraX family protein -
  EL130_RS00365 (NCTC10832_00069) rpsR 71323..71562 (-) 240 WP_000068664.1 30S ribosomal protein S18 -
  EL130_RS00370 (NCTC10832_00070) ssbA 71592..72086 (-) 495 WP_002261867.1 single-stranded DNA-binding protein Machinery gene
  EL130_RS00375 (NCTC10832_00071) rpsF 72104..72394 (-) 291 WP_002261866.1 30S ribosomal protein S6 -
  EL130_RS00380 (NCTC10832_00072) - 72550..72795 (-) 246 WP_002263367.1 hypothetical protein -
  EL130_RS00385 (NCTC10832_00073) - 73100..73303 (+) 204 WP_002267523.1 hypothetical protein -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26179.20 Da        Isoelectric Point: 6.4881

>NTDB_id=1121379 EL130_RS00355 WP_002278087.1 69591..70277(+) (hdrM) [Streptococcus mutans strain NCTC10832]
MKKNYFWYGLLGLLALYLITIAFIPGFHIFFSNMLMLALFFMLIALSNRSIFFFFLALGFLSIYLKDIFHFDYSTGPLFT
GIIIIGVILNSFFKPHYSYSYKGNHYFNMKQNANYIDNETDVFLKTLFSENTSYVTSQELNKIIIDTKFGEQSVDLSQAQ
FMTDSPEIHIDVSFGETNLRIPNNWKIINKTHSPFASISFSDFPSTNGDFINVTLTGTVAMGSLNIQY

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1121379 EL130_RS00355 WP_002278087.1 69591..70277(+) (hdrM) [Streptococcus mutans strain NCTC10832]
ATGAAAAAAAATTATTTTTGGTACGGTCTGCTTGGGCTTCTCGCACTTTACCTTATTACTATTGCTTTTATCCCGGGATT
TCATATTTTCTTTAGCAACATGTTGATGTTGGCCCTGTTCTTTATGTTAATAGCTTTGAGTAACAGGAGTATCTTCTTTT
TCTTTCTAGCCTTAGGTTTTCTTAGTATCTACTTGAAAGATATCTTTCATTTTGACTATTCTACCGGACCGCTTTTTACG
GGTATAATCATTATCGGCGTTATTTTAAATAGTTTCTTCAAACCACACTATTCTTATTCTTATAAAGGAAATCATTATTT
TAATATGAAACAAAATGCTAACTATATTGATAACGAAACAGATGTCTTTTTAAAAACACTTTTTTCTGAAAATACCAGTT
ATGTGACTTCTCAAGAATTAAATAAAATTATTATTGATACTAAGTTTGGAGAACAATCTGTTGATCTCTCTCAAGCTCAA
TTTATGACAGATTCTCCCGAAATTCATATAGATGTTAGCTTTGGTGAAACCAATCTGCGTATTCCAAACAACTGGAAAAT
CATCAATAAAACTCACTCCCCCTTTGCTTCCATTTCATTTTCAGATTTTCCTAGCACAAATGGTGATTTTATTAACGTTA
CATTGACTGGAACAGTGGCTATGGGATCTCTAAACATTCAATATTAA

Domains

Predicted by InterproScan.

Cell wall-active antibiotics response 4TMS YvqF (LiaF-like_C)

(128-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hdrM Streptococcus mutans UA159

98.684

100

0.987

Multiple sequence alignment