Detailed information
Bioinformatically predicted
Overview
| Name | clpX | Type | Regulator |
| Locus tag | EL136_RS03375 | Genome accession | NZ_LR134317 |
| Coordinates | 702652..703881 (+) | Length | 409 a.a. |
| NCBI ID | WP_043053130.1 | Uniprot ID | A0A7Z8ZVZ1 |
| Organism | Streptococcus equi subsp. zooepidemicus strain NCTC6180 | ||
| Function | require for competence development (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 650560..720676 | 702652..703881 | within | 0 |
Gene organization within MGE regions
Location: 650560..720676
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL136_RS03140 (NCTC6180_00649) | - | 650560..651822 (+) | 1263 | WP_014622976.1 | efflux RND transporter periplasmic adaptor subunit | - |
| EL136_RS03145 (NCTC6180_00650) | - | 651822..652532 (+) | 711 | WP_014622975.1 | ABC transporter ATP-binding protein | - |
| EL136_RS03150 (NCTC6180_00651) | - | 652544..653767 (+) | 1224 | WP_012515737.1 | ABC transporter permease | - |
| EL136_RS03155 (NCTC6180_00652) | - | 653760..654377 (+) | 618 | WP_038674239.1 | TVP38/TMEM64 family protein | - |
| EL136_RS03160 | - | 654429..654575 (+) | 147 | WP_154803809.1 | hypothetical protein | - |
| EL136_RS03165 (NCTC6180_00653) | rpsP | 654811..655083 (+) | 273 | WP_012677856.1 | 30S ribosomal protein S16 | - |
| EL136_RS03170 (NCTC6180_00654) | - | 655093..655332 (+) | 240 | WP_012515734.1 | KH domain-containing protein | - |
| EL136_RS03175 (NCTC6180_00655) | - | 655499..656137 (+) | 639 | WP_154803810.1 | recombinase family protein | - |
| EL136_RS03180 (NCTC6180_00656) | - | 656345..659590 (+) | 3246 | WP_232013941.1 | InlB B-repeat-containing protein | - |
| EL136_RS03185 (NCTC6180_00657) | - | 659599..660858 (-) | 1260 | WP_154803726.1 | ISL3-like element ISSeq1 family transposase | - |
| EL136_RS03190 | - | 660948..661253 (+) | 306 | WP_172954510.1 | LPXTG cell wall anchor domain-containing protein | - |
| EL136_RS03195 (NCTC6180_00659) | - | 661735..663077 (+) | 1343 | WP_172954511.1 | IS3 family transposase | - |
| EL136_RS03200 (NCTC6180_00660) | rimM | 663477..663995 (+) | 519 | WP_154803812.1 | ribosome maturation factor RimM | - |
| EL136_RS03205 (NCTC6180_00661) | trmD | 663985..664716 (+) | 732 | WP_012677861.1 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| EL136_RS03210 (NCTC6180_00662) | - | 664716..665708 (+) | 993 | WP_042670749.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| EL136_RS03215 (NCTC6180_00663) | - | 665840..666898 (+) | 1059 | WP_012515728.1 | PTS transporter subunit IIC | - |
| EL136_RS03220 (NCTC6180_00664) | - | 666910..667833 (+) | 924 | WP_154803813.1 | 2-dehydropantoate 2-reductase | - |
| EL136_RS03225 (NCTC6180_00665) | - | 668246..668959 (+) | 714 | WP_043030874.1 | DeoR/GlpR family DNA-binding transcription regulator | - |
| EL136_RS03230 (NCTC6180_00666) | pfkB | 668956..669867 (+) | 912 | WP_115266858.1 | 1-phosphofructokinase | - |
| EL136_RS03235 (NCTC6180_00667) | - | 669864..671810 (+) | 1947 | WP_154803814.1 | fructose-specific PTS transporter subunit EIIC | - |
| EL136_RS03240 (NCTC6180_00668) | - | 672334..672933 (+) | 600 | WP_043025924.1 | glycoside hydrolase family 73 protein | - |
| EL136_RS03245 (NCTC6180_00669) | - | 673493..673690 (+) | 198 | WP_154803815.1 | helix-turn-helix transcriptional regulator | - |
| EL136_RS03250 (NCTC6180_00670) | - | 673695..674138 (+) | 444 | WP_228275411.1 | hypothetical protein | - |
| EL136_RS03255 (NCTC6180_00671) | - | 674232..674462 (+) | 231 | WP_014622960.1 | hypothetical protein | - |
| EL136_RS11095 | - | 674544..674756 (+) | 213 | Protein_638 | conjugal transfer protein TraA | - |
| EL136_RS03265 (NCTC6180_00672) | - | 674870..676228 (+) | 1359 | WP_154803816.1 | SLC13 family permease | - |
| EL136_RS03270 (NCTC6180_00673) | - | 676675..677385 (+) | 711 | WP_012677869.1 | glycoside hydrolase family 73 protein | - |
| EL136_RS03275 (NCTC6180_00674) | - | 677602..677982 (+) | 381 | WP_037580974.1 | DUF1149 family protein | - |
| EL136_RS03280 (NCTC6180_00675) | - | 677982..678830 (+) | 849 | WP_014622955.1 | DegV family protein | - |
| EL136_RS03285 (NCTC6180_00676) | - | 678930..680141 (+) | 1212 | WP_172954532.1 | CCA tRNA nucleotidyltransferase | - |
| EL136_RS03290 (NCTC6180_00677) | - | 680134..682002 (+) | 1869 | WP_154803818.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| EL136_RS03295 (NCTC6180_00678) | - | 682107..683852 (+) | 1746 | WP_154803819.1 | ABC transporter ATP-binding protein | - |
| EL136_RS03300 (NCTC6180_00679) | - | 683852..685624 (+) | 1773 | WP_154803820.1 | ABC transporter ATP-binding protein | - |
| EL136_RS03305 (NCTC6180_00680) | gdhA | 685765..687114 (+) | 1350 | WP_043040660.1 | NADP-specific glutamate dehydrogenase | - |
| EL136_RS03310 (NCTC6180_00681) | - | 687247..687657 (+) | 411 | WP_021320823.1 | peptide deformylase | - |
| EL136_RS03315 (NCTC6180_00682) | - | 687851..689857 (-) | 2007 | WP_021320822.1 | surface-anchored 5'-nucleotidase | - |
| EL136_RS03320 (NCTC6180_00683) | - | 690307..692028 (+) | 1722 | WP_154804387.1 | ABC transporter ATP-binding protein | - |
| EL136_RS03325 (NCTC6180_00684) | - | 692030..693781 (+) | 1752 | WP_154803821.1 | ABC transporter ATP-binding protein | - |
| EL136_RS03330 (NCTC6180_00685) | mvk | 694311..695189 (+) | 879 | WP_012515704.1 | mevalonate kinase | - |
| EL136_RS03335 (NCTC6180_00686) | mvaD | 695171..696115 (+) | 945 | WP_154803822.1 | diphosphomevalonate decarboxylase | - |
| EL136_RS03340 (NCTC6180_00687) | - | 696108..697106 (+) | 999 | WP_154803823.1 | phosphomevalonate kinase | - |
| EL136_RS03345 (NCTC6180_00688) | fni | 697109..698101 (+) | 993 | WP_154803824.1 | type 2 isopentenyl-diphosphate Delta-isomerase | - |
| EL136_RS03350 (NCTC6180_00689) | - | 698376..699659 (-) | 1284 | WP_043030859.1 | hydroxymethylglutaryl-CoA reductase, degradative | - |
| EL136_RS03355 (NCTC6180_00690) | - | 699646..700824 (-) | 1179 | WP_043053132.1 | hydroxymethylglutaryl-CoA synthase | - |
| EL136_RS03360 (NCTC6180_00691) | - | 701009..701848 (+) | 840 | WP_042670718.1 | thymidylate synthase | - |
| EL136_RS03365 (NCTC6180_00692) | - | 701929..702426 (+) | 498 | WP_037581014.1 | dihydrofolate reductase | - |
| EL136_RS03370 (NCTC6180_00693) | - | 702446..702616 (+) | 171 | WP_012515696.1 | hypothetical protein | - |
| EL136_RS03375 (NCTC6180_00694) | clpX | 702652..703881 (+) | 1230 | WP_043053130.1 | ATP-dependent Clp protease ATP-binding subunit ClpX | Regulator |
| EL136_RS03380 (NCTC6180_00695) | yihA | 703891..704490 (+) | 600 | WP_012677890.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| EL136_RS03385 (NCTC6180_00696) | hupY | 704854..707859 (+) | 3006 | WP_154803825.1 | leucine-rich repeat adhesin HupY/LrrG | - |
| EL136_RS03390 (NCTC6180_00697) | - | 708049..710142 (-) | 2094 | WP_154803826.1 | AAA family ATPase | - |
| EL136_RS03395 (NCTC6180_00698) | ndk | 710512..710931 (+) | 420 | WP_037581033.1 | nucleoside-diphosphate kinase | - |
| EL136_RS03400 (NCTC6180_00699) | - | 711431..712237 (+) | 807 | WP_154803827.1 | DNA/RNA non-specific endonuclease | - |
| EL136_RS03405 (NCTC6180_00700) | - | 712534..713499 (-) | 966 | WP_154803828.1 | polysaccharide deacetylase family protein | - |
| EL136_RS03410 (NCTC6180_00701) | - | 713670..714953 (+) | 1284 | WP_043039005.1 | homoserine dehydrogenase | - |
| EL136_RS03415 (NCTC6180_00702) | thrB | 714955..715815 (+) | 861 | WP_037581040.1 | homoserine kinase | - |
| EL136_RS03420 (NCTC6180_00703) | - | 716086..717807 (+) | 1722 | WP_154803829.1 | IS1634-like element ISSeq4 family transposase | - |
| EL136_RS03425 (NCTC6180_00704) | - | 717986..719245 (+) | 1260 | WP_154803830.1 | bifunctional folylpolyglutamate synthase/dihydrofolate synthase | - |
| EL136_RS03430 (NCTC6180_00705) | folE | 719302..719868 (+) | 567 | WP_331271690.1 | GTP cyclohydrolase I FolE | - |
| EL136_RS03435 (NCTC6180_00706) | folP | 719876..720676 (+) | 801 | WP_012677899.1 | dihydropteroate synthase | - |
Sequence
Protein
Download Length: 409 a.a. Molecular weight: 45157.67 Da Isoelectric Point: 4.5698
>NTDB_id=1121266 EL136_RS03375 WP_043053130.1 702652..703881(+) (clpX) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVTKVRITKEAVEG
QSKPVLEIA
MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDILNQYVIGQER
AKRALSVAVYNHYKRISFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDDNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRI
LTEPRNALVKQYQALLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVTKVRITKEAVEG
QSKPVLEIA
Nucleotide
Download Length: 1230 bp
>NTDB_id=1121266 EL136_RS03375 WP_043053130.1 702652..703881(+) (clpX) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGCAATAACGTCTTTATTTGTAACGAATGTGTTGCCTTATCACAAGAAATCATCAAGGAAGAATTGGCAGAAGAGG
TTCTCGCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTCCTTGATATTTTAAACCAATACGTCATTGGTCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTATAATCATTACAAGAGGATTTCATTTACTGAGAGTCGTGACGATGATGATGT
GGATTTGCAAAAGTCAAACATTCTGATGATTGGACCAACAGGCTCAGGTAAGACCTTTTTAGCCCAGACTCTGGCTAAGA
GCCTTAATGTTCCATTTGCTATTGCTGATGCAACCTCTTTGACTGAAGCAGGTTATGTCGGAGAGGATGTGGAAAATATC
CTTCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAACGTGCAGAGCGTGGCATTATTTATGTTGATGAAATTGATAA
AATCGCTAAAAAAGGTGAGAATGTCTCTATCACTCGTGATGTATCAGGAGAAGGTGTCCAACAAGCCTTGCTAAAAATTA
TTGAGGGAACGGTTGCTAGTGTTCCACCGCAAGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTGTTTATCGTCGGAGGCGCCTTTGATGGTATCGAAGAGATTGTCAAGCAGCGCTTGGGGGAAAAGATCATTGG
CTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCCTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTAGCAGCGCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCTCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGTGCTCTGGAGGCTATTGCAGGCAGGGCTATTGAGCGCAAGACTGGTGCACGTGGTCTGAGGTCTATTATCGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAACCAAGGTACGCATTACTAAGGAAGCTGTCGAGGGC
CAATCAAAGCCCGTTTTAGAGATAGCCTAG
ATGGCAGGAAATCGTAGTAACGATATTAAGGTTCATTGCTCGTTTTGCGGCAAGAGCCAAGACGAAGTGAAAAAAATTAT
TGCAGGCAATAACGTCTTTATTTGTAACGAATGTGTTGCCTTATCACAAGAAATCATCAAGGAAGAATTGGCAGAAGAGG
TTCTCGCTGATCTGACTGAGGTACCAAAGCCAAAAGAGCTCCTTGATATTTTAAACCAATACGTCATTGGTCAGGAGCGT
GCTAAGAGAGCCTTATCAGTTGCAGTTTATAATCATTACAAGAGGATTTCATTTACTGAGAGTCGTGACGATGATGATGT
GGATTTGCAAAAGTCAAACATTCTGATGATTGGACCAACAGGCTCAGGTAAGACCTTTTTAGCCCAGACTCTGGCTAAGA
GCCTTAATGTTCCATTTGCTATTGCTGATGCAACCTCTTTGACTGAAGCAGGTTATGTCGGAGAGGATGTGGAAAATATC
CTTCTGAAATTAATTCAAGCCGCTGATTACAATGTTGAACGTGCAGAGCGTGGCATTATTTATGTTGATGAAATTGATAA
AATCGCTAAAAAAGGTGAGAATGTCTCTATCACTCGTGATGTATCAGGAGAAGGTGTCCAACAAGCCTTGCTAAAAATTA
TTGAGGGAACGGTTGCTAGTGTTCCACCGCAAGGTGGTCGTAAGCACCCAAACCAAGAGATGATACAGATTGATACCAAA
AATATCTTGTTTATCGTCGGAGGCGCCTTTGATGGTATCGAAGAGATTGTCAAGCAGCGCTTGGGGGAAAAGATCATTGG
CTTTGGGCAAAATAGTCGAAAGATTGATGACAATGCCTCCTATATGCAGGAGATCATTGCTGAGGATATTCAAAAATTTG
GTCTGATTCCCGAATTTATTGGACGCTTGCCTGTTGTAGCAGCGCTTGAGCAGCTTAATACTGAGGATTTGATTCGTATT
TTAACAGAGCCTAGAAATGCTCTTGTGAAGCAATATCAAGCCTTATTGTCATATGATGGCGTAGAGCTTGAGTTTGAAAA
GGGTGCTCTGGAGGCTATTGCAGGCAGGGCTATTGAGCGCAAGACTGGTGCACGTGGTCTGAGGTCTATTATCGAAGAAA
CCATGCTGGATATCATGTTTGAGGTGCCAAGCCAAGAGGAAGTAACCAAGGTACGCATTACTAAGGAAGCTGTCGAGGGC
CAATCAAAGCCCGTTTTAGAGATAGCCTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpX | Streptococcus mutans UA159 |
88.753 |
100 |
0.888 |
| clpX | Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 |
59.102 |
98.044 |
0.579 |