Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EL136_RS00855 Genome accession   NZ_LR134317
Coordinates   169055..170377 (+) Length   440 a.a.
NCBI ID   WP_154803607.1    Uniprot ID   A0A7Z8ZTH0
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6180     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 164055..175377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL136_RS00830 (NCTC6180_00170) - 164487..165128 (+) 642 WP_021321066.1 response regulator -
  EL136_RS00835 (NCTC6180_00171) - 165162..166562 (+) 1401 WP_154803606.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL136_RS00840 (NCTC6180_00172) - 166562..166924 (+) 363 WP_012516140.1 S1 RNA-binding domain-containing protein -
  EL136_RS00845 (NCTC6180_00173) cysK 167311..168237 (-) 927 WP_012677499.1 cysteine synthase A -
  EL136_RS00850 (NCTC6180_00174) - 168358..168999 (-) 642 WP_012677500.1 YigZ family protein -
  EL136_RS00855 (NCTC6180_00175) comFA/cflA 169055..170377 (+) 1323 WP_154803607.1 DEAD/DEAH box helicase Machinery gene
  EL136_RS00860 (NCTC6180_00176) - 170391..171017 (+) 627 WP_228274379.1 ComF family protein -
  EL136_RS00865 (NCTC6180_00177) hpf 171093..171641 (+) 549 WP_012677503.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EL136_RS00870 - 171825..173224 (-) 1400 Protein_170 ISNCY family transposase -

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 50042.21 Da        Isoelectric Point: 9.6746

>NTDB_id=1121256 EL136_RS00855 WP_154803607.1 169055..170377(+) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MENIENYYGRLLPERQCPKAVSVWACSLQSMIAKKGTLYCQRCSSLIEKAHQLPSGAYYCRACLVFGRNQSDRPLLYFPP
ASFPKAHYLRWQGQLTTYQAAVSHQLTNHVKLKQDTLVHAVTGAGKTEMMYEAIAAVVDKGGWVCVASPRVDVCIELEKR
LSRDFSCQICLMHAESEVYHRSPIIVATTHQLMTFYHAFDLLIIDEVDAFPFVNNRQLNHAAHQAAKADAVTVYLTATST
RDLERKVKQKELVKLTLARRFHGKPLVVPKYQRLFSLLETIHRGKLPRRLITLVKKQRATGYPLLIFFPLIELAEQCCQL
LQKYFPKETIAYASSQSSNRMAIIEQFRQGQITILISTTILERGVTFPTVDVFVLLANHRLYTSSSLIQISGRVGRSLER
PEGQVLFFHDGISKAMLKAVREIKDMNQKGYQNELSTLSQ

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1121256 EL136_RS00855 WP_154803607.1 169055..170377(+) (comFA/cflA) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGGAGAATATCGAAAATTACTATGGACGTCTTTTACCCGAAAGGCAATGCCCAAAGGCTGTTTCTGTCTGGGCTTGCAG
CTTACAAAGCATGATCGCTAAAAAAGGAACATTATACTGCCAACGCTGTAGCAGCTTAATTGAGAAAGCTCATCAGCTAC
CTAGCGGTGCTTACTACTGTAGAGCCTGTCTTGTTTTTGGTCGAAACCAATCTGATCGCCCCTTGCTCTATTTTCCACCG
GCTTCTTTTCCAAAGGCACATTATCTGAGGTGGCAAGGACAGCTCACGACATATCAGGCAGCTGTCTCTCATCAGCTTAC
TAACCATGTTAAGCTCAAGCAAGACACACTGGTTCATGCAGTTACCGGCGCTGGTAAAACAGAGATGATGTATGAAGCTA
TTGCAGCAGTTGTTGATAAAGGTGGCTGGGTCTGCGTTGCTAGTCCACGAGTTGATGTCTGTATAGAGCTTGAAAAACGA
CTATCGCGGGACTTTTCCTGTCAAATCTGCCTTATGCATGCTGAGTCAGAGGTTTATCATAGAAGCCCCATTATCGTTGC
CACAACACATCAATTGATGACCTTTTACCATGCTTTTGATCTGCTCATTATTGACGAAGTAGATGCCTTCCCCTTTGTCA
ATAATCGTCAATTAAACCATGCTGCTCATCAGGCTGCAAAAGCAGATGCAGTGACAGTATACCTAACAGCAACCTCTACA
AGAGACTTAGAGCGCAAGGTCAAGCAAAAAGAGCTTGTCAAATTGACATTAGCAAGAAGATTTCATGGCAAGCCCTTAGT
TGTCCCAAAGTATCAAAGATTATTCTCCCTTTTAGAGACTATCCATCGCGGGAAATTGCCTAGAAGGTTAATCACCCTAG
TCAAAAAACAAAGGGCAACAGGCTATCCCCTCTTAATCTTTTTCCCACTTATTGAGCTGGCTGAGCAGTGCTGTCAGCTG
CTGCAAAAGTATTTTCCTAAGGAAACTATTGCTTATGCTTCCAGTCAGTCATCAAATCGAATGGCTATCATTGAGCAATT
TAGACAAGGACAAATCACTATACTCATATCAACAACCATTTTAGAAAGAGGTGTGACCTTTCCGACCGTAGATGTCTTTG
TCTTGTTAGCCAATCATCGCCTTTACACAAGCAGCAGTCTTATTCAGATTTCAGGTCGCGTTGGGCGCTCCTTGGAAAGG
CCTGAAGGACAGGTGCTGTTTTTTCATGATGGCATTAGCAAGGCCATGCTCAAGGCAGTGCGGGAGATAAAGGATATGAA
TCAAAAAGGGTATCAAAATGAACTGTCTACTCTGTCACAATAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-396)

DEAD/DEAH box helicase (DEAD)

(98-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7Z8ZTH0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae R6

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae Rx1

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae D39

53.176

96.591

0.514
  comFA/cflA Streptococcus pneumoniae TIGR4

53.176

96.591

0.514
  comFA/cflA Streptococcus mitis SK321

53.176

96.591

0.514
  comFA/cflA Streptococcus mitis NCTC 12261

52.941

96.591

0.511
  comFA Lactococcus lactis subsp. cremoris KW2

48.214

89.091

0.43

Multiple sequence alignment