Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EL139_RS06280 Genome accession   NZ_LR134316
Coordinates   1226009..1227334 (+) Length   441 a.a.
NCBI ID   WP_111717280.1    Uniprot ID   A0A9X8T195
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1221009..1232334
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL139_RS06255 (NCTC6181_01273) - 1221687..1222328 (+) 642 WP_014612503.1 response regulator transcription factor -
  EL139_RS06260 (NCTC6181_01274) - 1222365..1223765 (+) 1401 WP_111717286.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  EL139_RS06265 (NCTC6181_01275) - 1223765..1224124 (+) 360 WP_111717284.1 S1 RNA-binding domain-containing protein -
  EL139_RS06270 (NCTC6181_01276) cysK 1224276..1225211 (-) 936 WP_012767420.1 cysteine synthase A -
  EL139_RS06275 (NCTC6181_01277) - 1225315..1225953 (-) 639 WP_111717282.1 YigZ family protein -
  EL139_RS06280 (NCTC6181_01278) comFA/cflA 1226009..1227334 (+) 1326 WP_111717280.1 DEAD/DEAH box helicase Machinery gene
  EL139_RS11610 (NCTC6181_01279) - 1227306..1227971 (+) 666 WP_111717278.1 ComF family protein -
  EL139_RS06290 (NCTC6181_01280) raiA 1228051..1228599 (+) 549 WP_003061817.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49365.55 Da        Isoelectric Point: 9.8406

>NTDB_id=1121231 EL139_RS06280 WP_111717280.1 1226009..1227334(+) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MESIENSYGRLFLKHQLPKEVNHLAKTLESIVTIKGKITCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGLLTSYQESISNKLVKNVHAKKLTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSRSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYSNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=1121231 EL139_RS06280 WP_111717280.1 1226009..1227334(+) (comFA/cflA) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGGAAAGTATCGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAACCATAAAAGGTAAAATCACTTGTCAACGTTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGTGGCACTTACTACTGCCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGTTATTAACGTCCTACCAAGAAAGTATTTCAAACAAATTAGT
CAAGAATGTTCATGCTAAAAAACTTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGAGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCCAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGGGTTACTCTTTTACATGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCAGCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAACTAGAGAAGTTGACATTAGCTAGACGATTCCACGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGCCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAACAAATTGCCTGTGTCTCTAGCCGATCAGCTGACAGAGTTAAAGACATTGATGCCTT
TCGTCAAGGAAAGAAAGGTATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGCGTGGATGTCTTTG
TGCTCATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTGGGGAGATCTATCGAAAGG
CCAACAGGGAAGGTGTACTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTCGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(105-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

52.844

95.692

0.506
  comFA/cflA Streptococcus pneumoniae D39

52.844

95.692

0.506
  comFA/cflA Streptococcus pneumoniae R6

52.844

95.692

0.506
  comFA/cflA Streptococcus pneumoniae TIGR4

52.844

95.692

0.506
  comFA/cflA Streptococcus mitis NCTC 12261

51.395

97.506

0.501
  comFA/cflA Streptococcus mitis SK321

51.529

96.372

0.497
  comFA Lactococcus lactis subsp. cremoris KW2

46.212

89.796

0.415
  comFA Latilactobacillus sakei subsp. sakei 23K

37.355

97.732

0.365

Multiple sequence alignment