Detailed information    

insolico Bioinformatically predicted

Overview

Name   eeP   Type   Regulator
Locus tag   EL135_RS09355 Genome accession   NZ_LR134312
Coordinates   1876107..1877375 (-) Length   422 a.a.
NCBI ID   WP_002356779.1    Uniprot ID   -
Organism   Enterococcus faecalis strain NCTC8745     
Function   processing of ComS (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1876692..1930704 1876107..1877375 flank -683


Gene organization within MGE regions


Location: 1876107..1930704
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL135_RS09355 (NCTC8745_01812) eeP 1876107..1877375 (-) 1269 WP_002356779.1 RIP metalloprotease RseP Regulator
  EL135_RS09360 (NCTC8745_01813) - 1878095..1878607 (-) 513 WP_002356778.1 AAA family ATPase -
  EL135_RS09365 (NCTC8745_01814) - 1878620..1878988 (-) 369 WP_002356777.1 ASCH domain-containing protein -
  EL135_RS09370 (NCTC8745_01815) - 1879016..1880086 (-) 1071 WP_002381584.1 hypothetical protein -
  EL135_RS09375 (NCTC8745_01816) - 1880145..1880981 (-) 837 WP_002356772.1 hypothetical protein -
  EL135_RS09380 (NCTC8745_01817) - 1881526..1881751 (-) 226 Protein_1741 helix-turn-helix transcriptional regulator -
  EL135_RS09385 - 1881804..1882052 (+) 249 WP_002356770.1 transposase -
  EL135_RS09390 (NCTC8745_01818) - 1882692..1884122 (-) 1431 WP_010816011.1 hypothetical protein -
  EL135_RS09395 (NCTC8745_01819) - 1884320..1887013 (+) 2694 WP_010816012.1 SpaA isopeptide-forming pilin-related protein -
  EL135_RS09400 (NCTC8745_01820) - 1887073..1887393 (+) 321 WP_010783786.1 hypothetical protein -
  EL135_RS09405 (NCTC8745_01821) - 1887409..1887807 (+) 399 WP_010783787.1 DUF961 family protein -
  EL135_RS09410 (NCTC8745_01822) - 1887824..1889260 (+) 1437 WP_010816013.1 FtsK/SpoIIIE domain-containing protein -
  EL135_RS09415 (NCTC8745_01823) - 1889637..1890938 (+) 1302 WP_010816014.1 XRE family transcriptional regulator -
  EL135_RS13635 (NCTC8745_01824) - 1890951..1891187 (+) 237 WP_010816015.1 antirestriction protein ArdA -
  EL135_RS13640 - 1891296..1891436 (+) 141 WP_229237036.1 hypothetical protein -
  EL135_RS09425 (NCTC8745_01825) - 1891433..1891807 (+) 375 WP_002336271.1 hypothetical protein -
  EL135_RS09430 (NCTC8745_01826) - 1891812..1892831 (+) 1020 WP_010783791.1 conjugal transfer protein -
  EL135_RS09435 (NCTC8745_01827) - 1892832..1893170 (+) 339 WP_003744475.1 TcpD family membrane protein -
  EL135_RS09440 (NCTC8745_01828) - 1893173..1893862 (+) 690 WP_010783792.1 TcpE family conjugal transfer membrane protein -
  EL135_RS09445 (NCTC8745_01829) - 1893877..1896399 (+) 2523 WP_010816016.1 ATP-binding protein -
  EL135_RS09450 (NCTC8745_01830) - 1896412..1898181 (+) 1770 WP_010816017.1 hypothetical protein -
  EL135_RS09455 (NCTC8745_01831) - 1898168..1899193 (+) 1026 WP_010783795.1 lysozyme family protein -
  EL135_RS09460 (NCTC8745_01832) - 1899306..1900076 (-) 771 WP_010816018.1 ABC transporter permease -
  EL135_RS09465 (NCTC8745_01833) - 1900069..1901004 (-) 936 WP_002372158.1 ABC transporter ATP-binding protein -
  EL135_RS09470 (NCTC8745_01834) - 1901082..1901261 (-) 180 WP_003744454.1 hypothetical protein -
  EL135_RS09475 (NCTC8745_01835) - 1901286..1902959 (-) 1674 WP_010816019.1 FAD-dependent oxidoreductase -
  EL135_RS09480 (NCTC8745_01836) arsB 1902980..1904035 (-) 1056 WP_003744449.1 arsenite efflux transporter membrane subunit ArsB -
  EL135_RS09485 (NCTC8745_01837) arsB 1904065..1905144 (-) 1080 WP_229237038.1 arsenite efflux transporter membrane subunit ArsB -
  EL135_RS09490 (NCTC8745_01838) arsA 1905224..1906966 (-) 1743 WP_002333378.1 arsenite efflux transporter ATPase subunit ArsA -
  EL135_RS09495 (NCTC8745_01839) arsR 1907002..1907367 (-) 366 WP_003744438.1 As(III)-sensing metalloregulatory transcriptional repressor ArsR -
  EL135_RS09500 (NCTC8745_01840) arsD 1907501..1907872 (-) 372 WP_000049327.1 arsenite efflux transporter metallochaperone ArsD -
  EL135_RS09505 (NCTC8745_01841) - 1907874..1908167 (-) 294 WP_002333381.1 metalloregulator ArsR/SmtB family transcription factor -
  EL135_RS09510 (NCTC8745_01842) arsA 1908258..1909997 (-) 1740 WP_010816020.1 arsenite efflux transporter ATPase subunit ArsA -
  EL135_RS09515 (NCTC8745_01843) arsD2 1910017..1910328 (-) 312 WP_010783799.1 arsenite efflux transporter metallochaperone ArsD-related protein -
  EL135_RS09520 (NCTC8745_01844) - 1910596..1911054 (+) 459 WP_010783800.1 hypothetical protein -
  EL135_RS09525 (NCTC8745_01845) - 1911072..1911476 (+) 405 WP_010783801.1 sigma-70 family RNA polymerase sigma factor -
  EL135_RS09530 (NCTC8745_01846) - 1911542..1911742 (+) 201 WP_002372173.1 helix-turn-helix domain-containing protein -
  EL135_RS09535 (NCTC8745_01847) - 1912364..1912570 (+) 207 WP_010783802.1 hypothetical protein -
  EL135_RS09540 (NCTC8745_01848) - 1912650..1913840 (+) 1191 WP_010783803.1 site-specific integrase -
  EL135_RS09545 (NCTC8745_01849) sufB 1913938..1915332 (-) 1395 WP_002356769.1 Fe-S cluster assembly protein SufB -
  EL135_RS09550 (NCTC8745_01850) sufU 1915351..1915818 (-) 468 WP_002356768.1 Fe-S cluster assembly sulfur transfer protein SufU -
  EL135_RS09555 (NCTC8745_01851) - 1915805..1917040 (-) 1236 WP_002394705.1 cysteine desulfurase -
  EL135_RS09560 (NCTC8745_01852) sufD 1917037..1918323 (-) 1287 WP_010816021.1 Fe-S cluster assembly protein SufD -
  EL135_RS09565 (NCTC8745_01853) sufC 1918338..1919108 (-) 771 WP_002356763.1 Fe-S cluster assembly ATPase SufC -
  EL135_RS09570 (NCTC8745_01854) frr 1919478..1920035 (-) 558 WP_002356762.1 ribosome recycling factor -
  EL135_RS09575 (NCTC8745_01855) pyrH 1920039..1920761 (-) 723 WP_002356761.1 UMP kinase -
  EL135_RS09580 (NCTC8745_01856) tsf 1921022..1921903 (-) 882 WP_002356760.1 translation elongation factor Ts -
  EL135_RS09585 (NCTC8745_01857) rpsB 1922009..1922794 (-) 786 WP_002356759.1 30S ribosomal protein S2 -
  EL135_RS09590 (NCTC8745_01858) - 1922978..1923415 (-) 438 WP_002356758.1 GNAT family N-acetyltransferase -
  EL135_RS09595 (NCTC8745_01859) - 1923435..1924211 (-) 777 WP_002356757.1 RNA methyltransferase -
  EL135_RS09600 (NCTC8745_01860) - 1924318..1924593 (+) 276 WP_002356756.1 acylphosphatase -
  EL135_RS09610 (NCTC8745_01861) yidC 1924760..1925692 (+) 933 WP_002356755.1 membrane protein insertase YidC -
  EL135_RS09615 (NCTC8745_01862) - 1925726..1925917 (-) 192 WP_002356753.1 DNA-directed RNA polymerase subunit alpha C-terminal domain-containing protein -
  EL135_RS09620 (NCTC8745_01863) glyS 1925957..1928041 (-) 2085 WP_002356751.1 glycine--tRNA ligase subunit beta -
  EL135_RS09625 (NCTC8745_01864) glyQ 1928043..1928951 (-) 909 WP_010816023.1 glycine--tRNA ligase subunit alpha -
  EL135_RS09635 (NCTC8745_01866) recO 1929597..1930385 (-) 789 WP_002356748.1 DNA repair protein RecO -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 46499.50 Da        Isoelectric Point: 6.9984

>NTDB_id=1121068 EL135_RS09355 WP_002356779.1 1876107..1877375(-) (eeP) [Enterococcus faecalis strain NCTC8745]
MKTIITFIIVFGILVLVHEFGHFYFAKRAGILVREFAIGMGPKIFAHRGKDGTTYTIRLLPIGGYVRMAGMGEDMTEITP
GMPLSVELNAVGNVVKINTSKKVQLPHSIPMEVVDFDLEKELFIKGYVNGNEEEETVYKVDHDATIIESDGTEVRIAPLD
VQFQSAKLSQRILTNFAGPMNNFILGFILFTLAVFLQGGVTDLNTNQIGQVIPNGPAAEAGLKENDKVLSINNQKIKKYE
DFTTIVQKNPEKPLTFVVERNGKEEQLTVTPEKQKVEKQTIGKVGVYPYMKTDLPSKLMGGIQDTLNSTTQIFKALGSLF
TGFSLNKLGGPVMMFKLSQEASNAGVTTVVFLMAMLSMNLGIINLLPIPALDGGKIVLNIIEGVRGKPISPEKEGIITLI
GFGFVMVLMVLVTWNDIQRFFF

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=1121068 EL135_RS09355 WP_002356779.1 1876107..1877375(-) (eeP) [Enterococcus faecalis strain NCTC8745]
ATGAAAACAATTATCACATTCATTATTGTCTTCGGTATTCTTGTCCTCGTACATGAATTTGGCCACTTTTATTTTGCAAA
ACGAGCGGGTATTTTAGTTCGTGAGTTTGCAATCGGAATGGGACCAAAGATTTTTGCGCATCGTGGAAAAGATGGCACCA
CTTATACGATTCGCTTATTGCCAATTGGTGGCTATGTGCGAATGGCTGGGATGGGCGAAGACATGACAGAAATCACACCA
GGTATGCCTCTATCTGTTGAGTTAAATGCCGTGGGTAATGTGGTTAAAATTAATACAAGTAAAAAAGTACAATTACCTCA
TAGTATTCCGATGGAAGTCGTTGATTTTGATCTTGAAAAAGAATTATTCATCAAGGGCTATGTCAATGGAAACGAGGAAG
AAGAAACCGTTTATAAAGTTGACCATGATGCAACGATTATTGAAAGTGATGGGACCGAGGTGCGGATTGCGCCACTTGAC
GTTCAATTTCAATCAGCGAAATTATCGCAACGCATTTTGACGAACTTTGCGGGACCCATGAATAACTTTATCTTAGGGTT
TATTCTGTTTACGTTAGCGGTCTTTCTACAAGGAGGCGTCACTGATTTAAACACGAACCAAATTGGACAAGTGATTCCTA
ATGGCCCAGCCGCAGAAGCTGGGTTGAAAGAAAACGATAAAGTCTTATCGATCAATAATCAAAAAATCAAAAAATACGAA
GATTTTACAACCATTGTGCAGAAGAACCCCGAAAAGCCGTTAACGTTCGTAGTTGAGCGTAACGGCAAAGAAGAGCAACT
AACAGTGACACCAGAAAAACAAAAAGTGGAAAAACAAACGATTGGTAAAGTCGGCGTTTATCCTTATATGAAAACCGATT
TACCGTCAAAATTGATGGGTGGTATTCAGGATACTTTGAATAGTACGACACAGATTTTTAAAGCACTCGGCTCACTATTC
ACAGGTTTTAGTTTAAACAAACTAGGTGGTCCAGTCATGATGTTTAAACTATCACAAGAAGCATCCAATGCTGGGGTAAC
GACAGTTGTATTCTTAATGGCCATGTTGTCAATGAACTTAGGGATTATTAATTTGTTGCCGATCCCAGCTTTAGATGGCG
GGAAAATTGTCTTAAACATTATTGAAGGTGTACGTGGAAAACCAATTAGTCCTGAAAAAGAAGGCATCATTACGTTAATT
GGCTTTGGGTTTGTCATGGTGTTAATGGTGTTAGTTACTTGGAACGATATTCAACGCTTTTTCTTTTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_6)

(208-260)

Peptidase family M50 (Peptidase_M50)

(6-408)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  eeP Streptococcus thermophilus LMG 18311

53.738

100

0.545
  eeP Streptococcus thermophilus LMD-9

53.738

100

0.545

Multiple sequence alignment